Amyloid-Binding Alcohol Dehydrogenase (ABAD) Inhibitors for the Treatment of Alzheimer’s Disease: Miniperspective A Morsy, PC Trippier Journal of medicinal chemistry 62 (9), 4252-4264, 2018 | 59 | 2018 |
Current and emerging pharmacological targets for the treatment of Alzheimer’s disease A Morsy, PC Trippier Journal of Alzheimer's Disease 72 (s1), S145-S176, 2019 | 36 | 2019 |
An iPSC-Derived Neuron Model of CLN3 Disease Facilitates Small Molecule Phenotypic Screening N Kinarivala, A Morsy, R Patel, A Carmona, MS Sajib, S Raut, C Mikelis, ... ACS Pharmacology & Translational Science, 2020 | 21 | 2020 |
Reversal of Apalutamide and Darolutamide Aldo-Keto Reductase 1C3-Mediated Resistance by a Small Molecule Inhibitor A Morsy, PC Trippier ACS Chemical Biology 15 (3), 646-650, 2020 | 18 | 2020 |
Functionalized Allopurinols Targeting Amyloid-Binding Alcohol Dehydrogenase Rescue Aβ-Induced Mitochondrial Dysfunction A Morsy, K Maddeboina, J Gao, H Wang, J Valdez, LF Dow, X Wang, ... ACS Chemical Neuroscience 13 (14), 2176-2190, 2022 | 13 | 2022 |
Current Status of Healthy Aging and Dementia Research: A Symposium Summary PH Reddy, RH Swerdlow, J Culberson, D Kang, TL Mitchell, Q Smith, ... Journal of Alzheimer's Disease 72 (s1), S11-S35, 2019 | 8 | 2019 |
Patient-derived induced pluripotent stem cell models for phenotypic screening in the neuronal ceroid lipofuscinoses A Morsy, AV Carmona, PC Trippier Molecules 26 (20), 6235, 2021 | 7 | 2021 |
Aldo-Keto Reductase 1C3 Inhibitor Prodrug Improves Pharmacokinetic Profile and Demonstrates In Vivo Efficacy in a Prostate Cancer Xenograft Model K Maddeboina, SK Jonnalagadda, A Morsy, L Duan, YS Chhonker, ... Journal of Medicinal Chemistry 66 (14), 9894-9915, 2023 | 3 | 2023 |
Design, Synthesis and Evaluation of Novel Inhibitors of Type 5 and 10 17β-Hydroxysteroid Dehydrogenases A Morsy | | 2021 |
Small Molecules that Rescue Multiple Phenotypic Aberrations in an iPSC-Derived Neuron Model of CLN3 Disease N Kinarivala, A Morsy, R Patel, A Carmona, M Sajib, S Raut, C M Mikelis, ... ChemRxiv, 2020 | | 2020 |
Synthesis and Structure-Activity Relationship Studies of AG18051 and Its Analogs in the Treatment of Alzheimer's Disease by Inhibiting A beta-ABAD Interaction. A Morsy, PC Trippier JOURNAL OF ALZHEIMERS DISEASE 72, S33-S34, 2019 | | 2019 |