| Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl) imidazole at 2.0-Å resolution SC Gay, MB Shah, JC Talakad, K Maekawa, AG Roberts, PR Wilderman, ... Molecular pharmacology 77 (4), 529-538, 2010 | 103 | 2010 |
| Structural features of cytochromes P450 and ligands that affect drug metabolism as revealed by x-ray crystallography and NMR SC Gay, AG Roberts, JR Halpert Future Medicinal Chemistry 2 (9), 1451-1468, 2010 | 88 | 2010 |
| Structures of cytochrome P450 2B4 complexed with the antiplatelet drugs ticlopidine and clopidogrel SC Gay, AG Roberts, K Maekawa, JC Talakad, WX Hong, Q Zhang, ... Biochemistry 49 (40), 8709-8720, 2010 | 47 | 2010 |
| Crystal Structures of Cytochrome P450 2B4 in Complex with the Inhibitor 1-Biphenyl-4-methyl-1H-imidazole: Ligand-Induced Structural Response through α-Helical … SC Gay, L Sun, K Maekawa, JR Halpert, CD Stout Biochemistry 48 (22), 4762-4771, 2009 | 47 | 2009 |
| Structural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivator tert-Butylphenylacetylene: Insight into Partial … SC Gay, H Zhang, PR Wilderman, AG Roberts, T Liu, S Li, H Lin, Q Zhang, ... Biochemistry 50 (22), 4903-4911, 2011 | 40 | 2011 |
| Investigation by site‐directed mutagenesis of the role of cytochrome P450 2B4 non‐active‐site residues in protein–ligand interactions based on crystal structures of the ligand … PR Wilderman, SC Gay, HH Jang, Q Zhang, CD Stout, JR Halpert The FEBS journal 279 (9), 1607-1620, 2012 | 34 | 2012 |
| Structure and function of cytochromes P450 2B: from mechanism-based inactivators to X-ray crystal structures and back JR Halpert Drug Metabolism and Disposition 39 (7), 1113-1121, 2011 | 30 | 2011 |
| Potent mechanism-based inactivation of cytochrome P450 2B4 by 9-ethynylphenanthrene: implications for allosteric modulation of cytochrome P450 catalysis H Zhang, SC Gay, M Shah, M Foroozesh, J Liu, Y Osawa, Q Zhang, ... Biochemistry 52 (2), 355-364, 2013 | 29 | 2013 |
| Design and synthesis of novel spiro derivatives as potent and reversible monoacylglycerol lipase (MAGL) inhibitors: bioisosteric transformation from 3-oxo-3, 4-dihydro-2 H … S Ikeda, H Sugiyama, H Tokuhara, M Murakami, M Nakamura, Y Oguro, ... Journal of Medicinal Chemistry 64 (15), 11014-11044, 2021 | 23 | 2021 |
| Structure of the two-domain hexameric APS kinase from Thiobacillus denitrificans: structural basis for the absence of ATP sulfurylase activity SC Gay, IH Segel, AJ Fisher Acta Crystallographica Section D: Biological Crystallography 65 (10), 1021-1031, 2009 | 13 | 2009 |
| Kinetic properties of ATP sulfurylase and APS kinase from Thiobacillus denitrificans SC Gay, JL Fribourgh, PD Donohoue, IH Segel, AJ Fisher Archives of biochemistry and biophysics 489 (1-2), 110-117, 2009 | 12 | 2009 |
| Design and synthesis of aryl-piperidine derivatives as potent and selective PET tracers for cholesterol 24-hydroxylase (CH24H) S Ikeda, Y Kajita, M Miyamoto, K Matsumiya, T Ishii, T Nishi, SC Gay, ... European Journal of Medicinal Chemistry 240, 114612, 2022 | 2 | 2022 |
| Structural and functional studies of sulfate activating enzymes SC Gay University of California, Davis, 2008 | | 2008 |
