Intercellular coupling confers robustness against mutations in the SCN circadian clock network AC Liu, DK Welsh, CH Ko, HG Tran, EE Zhang, AA Priest, ED Buhr, ... Cell 129 (3), 605-616, 2007 | 808 | 2007 |
Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis EE Zhang, Y Liu, R Dentin, PY Pongsawakul, AC Liu, T Hirota, ... Nature Medicine 16 (10), 1152-1156, 2010 | 630 | 2010 |
Clocks not winding down: unravelling circadian networks EE Zhang, SA Kay Nature Reviews Molecular Cell Biology 11 (11), 764-776, 2010 | 506 | 2010 |
A genome-wide RNAi screen for modifiers of the circadian clock in human cells EE Zhang, AC Liu, T Hirota, LJ Miraglia, G Welch, PY Pongsawakul, X Liu, ... Cell 139 (1), 199-210, 2009 | 492 | 2009 |
Redundant function of REV-ERBα and β and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms AC Liu, HG Tran, EE Zhang, AA Priest, DK Welsh, SA Kay PLoS Genetics 4 (2), e1000023, 2008 | 449 | 2008 |
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism EE Zhang, E Chapeau, K Hagihara, GS Feng Proceedings of the National Academy of Sciences 101 (45), 16064-16069, 2004 | 277 | 2004 |
High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase T Hirota, JW Lee, WG Lewis, EE Zhang, G Breton, X Liu, M Garcia, ... PLoS Biology 8 (12), e1000559, 2010 | 275 | 2010 |
Reciprocal Regulation between the Circadian Clock and Hypoxia Signaling at the Genome Level in Mammals Y Wu, D Tang, N Liu, W Xiong, H Huang, Y Li, Z Ma, H Zhao, P Chen, X Qi, ... Cell Metabolism 25 (1), 73–85, 2017 | 254 | 2017 |
Emergence of noise-induced oscillations in the central circadian pacemaker CH Ko, YR Yamada, DK Welsh, ED Buhr, AC Liu, EE Zhang, MR Ralph, ... PLoS Biology 8 (10), e1000513, 2010 | 246 | 2010 |
Guidelines for Genome-Scale Analysis of Biological Rhythms ME Hughes, KC Abruzzi, R Allada, R Anafi, AB Arpat, G Asher, P Baldi, ... Journal of Biological Rhythms 32 (5), 380-393, 2017 | 233 | 2017 |
Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1 S Peng, W Xiao, D Ju, B Sun, N Hou, Q Liu, Y Wang, H Zhao, C Gao, ... Science Translational Medicine 11 (488), eaau7116, 2019 | 227 | 2019 |
Identification of Shp-2 as a Stat5A phosphatase Y Chen, R Wen, S Yang, J Schuman, EE Zhang, T Yi, GS Feng, D Wang Journal of Biological Chemistry 278 (19), 16520-16527, 2003 | 165 | 2003 |
Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality Y Ke, EE Zhang, K Hagihara, D Wu, Y Pang, R Klein, T Curran, B Ranscht, ... Molecular and Cellular Biology 27 (19), 6706-6717, 2007 | 154 | 2007 |
The circadian clock gene Bmal1 acts as a potential anti-oncogene in pancreatic cancer by activating the p53 tumor suppressor pathway W Jiang, S Zhao, X Jiang, E Zhang, G Hu, B Hu, P Zheng, J Xiao, Z Lu, ... Cancer Letters 371 (2), 314-325, 2016 | 150 | 2016 |
Concerted functions of Gab1 and Shp2 in liver regeneration and hepatoprotection EA Bard-Chapeau, J Yuan, N Droin, S Long, EE Zhang, TV Nguyen, ... Molecular and Cellular Biology 26 (12), 4664-4674, 2006 | 126 | 2006 |
Conditional deletion of Shp2 tyrosine phosphatase in thymocytes suppresses both pre-TCR and TCR signals TV Nguyen, Y Ke, EE Zhang, GS Feng The Journal of Immunology 177 (9), 5990-5996, 2006 | 105 | 2006 |
Bud specific N-sulfation of heparan sulfate regulates Shp2-dependent FGF signaling during lacrimal gland induction Y Pan, C Carbe, A Powers, EE Zhang, JD Esko, K Grobe, GS Feng, ... Development 135 (2), 301-310, 2008 | 101 | 2008 |
Deletion of Gab1 in the liver leads to enhanced glucose tolerance and improved hepatic insulin action EA Bard-Chapeau, AL Hevener, S Long, EE Zhang, JM Olefsky, GS Feng Nature Medicine 11 (5), 567-571, 2005 | 100 | 2005 |
Diurnal oscillations of endogenous H2O2 sustained by p66 Shc regulate circadian clocks JF Pei, XK Li, WQ Li, Q Gao, Y Zhang, XM Wang, JQ Fu, SS Cui, JH Qu, ... Nature Cell Biology 21, 1553-1564, 2019 | 96 | 2019 |
Long-term in vivo recording of circadian rhythms in brains of freely moving mice L Mei, Y Fan, X Lv, DK Welsh, C Zhan, EE Zhang Proceedings of the National Academy of Sciences 115 (16), 4276-4281, 2018 | 90 | 2018 |