| Intestinal ABCA1 directly contributes to HDL biogenesis in vivo LR Brunham, JK Kruit, J Iqbal, C Fievet, JM Timmins, TD Pape, ... The Journal of clinical investigation 116 (4), 1052-1062, 2006 | 651 | 2006 |
| β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment LR Brunham, JK Kruit, TD Pape, JM Timmins, AQ Reuwer, Z Vasanji, ... Nature medicine 13 (3), 340-347, 2007 | 475 | 2007 |
| Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice R Out, M Hoekstra, RB Hildebrand, JK Kruit, I Meurs, Z Li, F Kuipers, ... Arteriosclerosis, thrombosis, and vascular biology 26 (10), 2295-2300, 2006 | 271 | 2006 |
| Reduced cholesterol absorption upon PPARδ activation coincides with decreased intestinal expression of NPC1L1 JN van Der Veen, JK Kruit, R Havinga, JFW Baller, G Chimini, S Lestavel, ... Journal of lipid research 46 (3), 526-534, 2005 | 261 | 2005 |
| Lymphocyte-derived exosomal microRNAs promote pancreatic β cell death and may contribute to type 1 diabetes development C Guay, JK Kruit, S Rome, V Menoud, NL Mulder, A Jurdzinski, ... Cell metabolism 29 (2), 348-361. e6, 2019 | 230 | 2019 |
| Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice JK Kruit, T Plösch, R Havinga, R Boverhof, PHE Groot, AK Groen, ... Gastroenterology 128 (1), 147-156, 2005 | 216 | 2005 |
| Emerging roles of the intestine in control of cholesterol metabolism JK Kruit, AK Groen, TJ van Berkel, F Kuipers World journal of gastroenterology: WJG 12 (40), 6429, 2006 | 199 | 2006 |
| A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans V Acuña-Alonzo, T Flores-Dorantes, JK Kruit, T Villarreal-Molina, ... Human Molecular Genetics 19 (14), 2877-2885, 2010 | 193 | 2010 |
| Cholesterol in islet dysfunction and type 2 diabetes LR Brunham, JK Kruit, CB Verchere, MR Hayden The Journal of clinical investigation 118 (2), 403-408, 2008 | 185 | 2008 |
| HDL and LDL cholesterol significantly influence β-cell function in type 2 diabetes mellitus JK Kruit, LR Brunham, CB Verchere, MR Hayden Current opinion in lipidology 21 (3), 178-185, 2010 | 183 | 2010 |
| Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function JM Karasinska, F Rinninger, D Lütjohann, P Ruddle, S Franciosi, JK Kruit, ... Journal of Neuroscience 29 (11), 3579-3589, 2009 | 156 | 2009 |
| Tissue-specific induction of intestinal ABCA1 expression with a liver X receptor agonist raises plasma HDL cholesterol levels LR Brunham, JK Kruit, TD Pape, JS Parks, F Kuipers, MR Hayden Circulation research 99 (7), 672-674, 2006 | 146 | 2006 |
| Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell function … JK Kruit, PHC Kremer, L Dai, R Tang, P Ruddle, W De Haan, LR Brunham, ... Diabetologia 53, 1110-1119, 2010 | 143 | 2010 |
| Carriers of loss-of-function mutations in ABCA1 display pancreatic β-cell dysfunction M Vergeer, LR Brunham, J Koetsveld, JK Kruit, CB Verchere, ... Diabetes care 33 (4), 869-874, 2010 | 142 | 2010 |
| Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function JK Kruit, N Wijesekara, C Westwell-Roper, T Vanmierlo, W De Haan, ... Diabetes 61 (3), 659-664, 2012 | 137 | 2012 |
| Islet cholesterol accumulation due to loss of ABCA1 leads to impaired exocytosis of insulin granules JK Kruit, N Wijesekara, JEM Fox, XQ Dai, LR Brunham, GJ Searle, ... Diabetes 60 (12), 3186-3196, 2011 | 130 | 2011 |
| Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter T Plösch, JK Kruit, VW Bloks, NCA Huijkman, R Havinga, GS Duchateau, ... The Journal of nutrition 136 (8), 2135-2140, 2006 | 124 | 2006 |
| ABCA1 influences neuroinflammation and neuronal death JM Karasinska, W de Haan, S Franciosi, P Ruddle, J Fan, JK Kruit, ... Neurobiology of disease 54, 445-455, 2013 | 84 | 2013 |
| Cholesterol in β-cell dysfunction: The emerging connection between HDL cholesterol and Type 2 diabetes LR Brunham, JK Kruit, MR Hayden, CB Verchere Current diabetes reports 10, 55-60, 2010 | 75 | 2010 |
| Plant sterols cause macrothrombocytopenia in a mouse model of sitosterolemia JK Kruit, AL Drayer, VW Bloks, N Blom, SG Olthof, PJJ Sauer, G De Haan, ... Journal of Biological Chemistry 283 (10), 6281-6287, 2008 | 51 | 2008 |
