How do microRNAs regulate gene expression? IG Cannell, YW Kong, M Bushell Biochemical Society Transactions 36 (6), 1224-1231, 2008 | 477 | 2008 |
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling SR Floyd, ME Pacold, Q Huang, SM Clarke, FC Lam, IG Cannell, ... Nature 498 (7453), 246-250, 2013 | 350 | 2013 |
The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene YW Kong, IG Cannell, CH de Moor, K Hill, PG Garside, TL Hamilton, ... Proceedings of the National Academy of Sciences 105 (26), 8866-8871, 2008 | 244 | 2008 |
Clonal decomposition and DNA replication states defined by scaled single-cell genome sequencing E Laks, A McPherson, H Zahn, D Lai, A Steif, J Brimhall, J Biele, B Wang, ... Cell 179 (5), 1207-1221. e22, 2019 | 205 | 2019 |
p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication IG Cannell, YW Kong, SJ Johnston, ML Chen, HM Collins, HC Dobbyn, ... Proceedings of the National Academy of Sciences 107 (12), 5375-5380, 2010 | 203 | 2010 |
The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis TR Kress, IG Cannell, AB Brenkman, B Samans, M Gaestel, P Roepman, ... Molecular cell 41 (4), 445-457, 2011 | 182 | 2011 |
Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes D Ferland-McCollough, DS Fernandez-Twinn, IG Cannell, H David, ... Cell Death & Differentiation 19 (6), 1003-1012, 2012 | 179 | 2012 |
Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes IR Powley, A Kondrashov, LA Young, HC Dobbyn, K Hill, IG Cannell, ... Genes & development 23 (10), 1207-1220, 2009 | 172 | 2009 |
A reversible gene-targeting strategy identifies synthetic lethal interactions between MK2 and p53 in the DNA damage response in vivo S Morandell, HC Reinhardt, IG Cannell, JS Kim, DM Ruf, T Mitra, ... Cell reports 5 (4), 868-877, 2013 | 103 | 2013 |
A pleiotropic RNA-binding protein controls distinct cell cycle checkpoints to drive resistance of p53-defective tumors to chemotherapy IG Cannell, KA Merrick, S Morandell, CQ Zhu, CJ Braun, RA Grant, ... Cancer cell 28 (5), 623-637, 2015 | 91 | 2015 |
Regulation of Myc by miR-34c: A mechanism to prevent genomic instability? I Cannell, M Bushell Cell Cycle 9 (14), 2798-2802, 2010 | 78 | 2010 |
Is post-transcriptional stabilization, splicing and translation of selective mRNAs a key to the DNA damage response? HC Reinhardt, IG Cannell, S Morandell, MB Yaffe Cell Cycle 10 (1), 23-27, 2011 | 51 | 2011 |
A common polymorphism in the 5′ UTR of ERCC5 creates an upstream ORF that confers resistance to platinum-based chemotherapy J Somers, LA Wilson, JP Kilday, E Horvilleur, IG Cannell, TAA Pöyry, ... Genes & development 29 (18), 1891-1896, 2015 | 41 | 2015 |
Transite: a computational motif-based analysis platform that identifies RNA-binding proteins modulating changes in gene expression K Krismer, MA Bird, S Varmeh, ED Handly, A Gattinger, T Bernwinkler, ... Cell reports 32 (8), 2020 | 38 | 2020 |
FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy IG Cannell, K Sawicka, I Pearsall, SA Wild, L Deighton, SM Pearsall, ... Cell Reports 42 (8), 2023 | 15 | 2023 |
Lineage plasticity in SCLC generates non-neuroendocrine cells primed for vasculogenic mimicry SM Pearsall, SC Williamson, S Humphrey, E Hughes, D Morgan, ... Journal of Thoracic Oncology 18 (10), 1362-1385, 2023 | 5 | 2023 |
An RNA damage response network mediates the lethality of 5-FU in clinically relevant tumor types JK Chen, KA Merrick, YW Kong, A Izrael-Tomasevic, G Eng, ED Handly, ... bioRxiv, 2023 | 4 | 2023 |
Clonal transcriptomics identifies mechanisms of chemoresistance and empowers rational design of combination therapies SA Wild, IG Cannell, A Nicholls, K Kania, D Bressan, GJ Hannon, ... elife 11, e80981, 2022 | 4 | 2022 |
The in vitro dynamics of pseudo-vascular network formation ME Oraiopoulou, DL Couturier, EV Bunce, IG Cannell, PW Sweeney, ... British Journal of Cancer, 1-11, 2024 | 1 | 2024 |
Lineage plasticity in small cell lung cancer generates non-neuroendocrine cells primed for vascular mimicry SM Pearsall, SC Williamson, FG Marqués, S Humphrey, E Hughes, ... Cancer Research 81 (13_Supplement), 2653-2653, 2021 | 1 | 2021 |