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Ian G Cannell
Ian G Cannell
CRUK Cambridge Institute, University of Cambridge, Massachusetts Institute of Technology
在 cruk.cam.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
How do microRNAs regulate gene expression?
IG Cannell, YW Kong, M Bushell
Biochemical Society Transactions 36 (6), 1224-1231, 2008
4772008
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
SR Floyd, ME Pacold, Q Huang, SM Clarke, FC Lam, IG Cannell, ...
Nature 498 (7453), 246-250, 2013
3502013
The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene
YW Kong, IG Cannell, CH de Moor, K Hill, PG Garside, TL Hamilton, ...
Proceedings of the National Academy of Sciences 105 (26), 8866-8871, 2008
2442008
Clonal decomposition and DNA replication states defined by scaled single-cell genome sequencing
E Laks, A McPherson, H Zahn, D Lai, A Steif, J Brimhall, J Biele, B Wang, ...
Cell 179 (5), 1207-1221. e22, 2019
2052019
p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication
IG Cannell, YW Kong, SJ Johnston, ML Chen, HM Collins, HC Dobbyn, ...
Proceedings of the National Academy of Sciences 107 (12), 5375-5380, 2010
2032010
The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis
TR Kress, IG Cannell, AB Brenkman, B Samans, M Gaestel, P Roepman, ...
Molecular cell 41 (4), 445-457, 2011
1822011
Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes
D Ferland-McCollough, DS Fernandez-Twinn, IG Cannell, H David, ...
Cell Death & Differentiation 19 (6), 1003-1012, 2012
1792012
Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes
IR Powley, A Kondrashov, LA Young, HC Dobbyn, K Hill, IG Cannell, ...
Genes & development 23 (10), 1207-1220, 2009
1722009
A reversible gene-targeting strategy identifies synthetic lethal interactions between MK2 and p53 in the DNA damage response in vivo
S Morandell, HC Reinhardt, IG Cannell, JS Kim, DM Ruf, T Mitra, ...
Cell reports 5 (4), 868-877, 2013
1032013
A pleiotropic RNA-binding protein controls distinct cell cycle checkpoints to drive resistance of p53-defective tumors to chemotherapy
IG Cannell, KA Merrick, S Morandell, CQ Zhu, CJ Braun, RA Grant, ...
Cancer cell 28 (5), 623-637, 2015
912015
Regulation of Myc by miR-34c: A mechanism to prevent genomic instability?
I Cannell, M Bushell
Cell Cycle 9 (14), 2798-2802, 2010
782010
Is post-transcriptional stabilization, splicing and translation of selective mRNAs a key to the DNA damage response?
HC Reinhardt, IG Cannell, S Morandell, MB Yaffe
Cell Cycle 10 (1), 23-27, 2011
512011
A common polymorphism in the 5′ UTR of ERCC5 creates an upstream ORF that confers resistance to platinum-based chemotherapy
J Somers, LA Wilson, JP Kilday, E Horvilleur, IG Cannell, TAA Pöyry, ...
Genes & development 29 (18), 1891-1896, 2015
412015
Transite: a computational motif-based analysis platform that identifies RNA-binding proteins modulating changes in gene expression
K Krismer, MA Bird, S Varmeh, ED Handly, A Gattinger, T Bernwinkler, ...
Cell reports 32 (8), 2020
382020
FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy
IG Cannell, K Sawicka, I Pearsall, SA Wild, L Deighton, SM Pearsall, ...
Cell Reports 42 (8), 2023
152023
Lineage plasticity in SCLC generates non-neuroendocrine cells primed for vasculogenic mimicry
SM Pearsall, SC Williamson, S Humphrey, E Hughes, D Morgan, ...
Journal of Thoracic Oncology 18 (10), 1362-1385, 2023
52023
An RNA damage response network mediates the lethality of 5-FU in clinically relevant tumor types
JK Chen, KA Merrick, YW Kong, A Izrael-Tomasevic, G Eng, ED Handly, ...
bioRxiv, 2023
42023
Clonal transcriptomics identifies mechanisms of chemoresistance and empowers rational design of combination therapies
SA Wild, IG Cannell, A Nicholls, K Kania, D Bressan, GJ Hannon, ...
elife 11, e80981, 2022
42022
The in vitro dynamics of pseudo-vascular network formation
ME Oraiopoulou, DL Couturier, EV Bunce, IG Cannell, PW Sweeney, ...
British Journal of Cancer, 1-11, 2024
12024
Lineage plasticity in small cell lung cancer generates non-neuroendocrine cells primed for vascular mimicry
SM Pearsall, SC Williamson, FG Marqués, S Humphrey, E Hughes, ...
Cancer Research 81 (13_Supplement), 2653-2653, 2021
12021
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