Quantitative flux analysis reveals folate-dependent NADPH production J Fan, J Ye, JJ Kamphorst, T Shlomi, CB Thompson, JD Rabinowitz Nature 510 (7504), 298-302, 2014 | 1072 | 2014 |
Associating genes and protein complexes with disease via network propagation O Vanunu, O Magger, E Ruppin, T Shlomi, R Sharan PLoS computational biology 6 (1), e1000641, 2010 | 952 | 2010 |
Network-based prediction of human tissue-specific metabolism T Shlomi, MN Cabili, MJ Herrgård, BØ Palsson, E Ruppin Nature biotechnology 26 (9), 1003-1010, 2008 | 742 | 2008 |
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence J Kaplon, L Zheng, K Meissl, B Chaneton, VA Selivanov, G Mackay, ... Nature 498 (7452), 109-112, 2013 | 636 | 2013 |
Regulatory on/off minimization of metabolic flux changes after genetic perturbations T Shlomi, O Berkman, E Ruppin Proceedings of the national academy of sciences 102 (21), 7695-7700, 2005 | 592 | 2005 |
Predicting selective drug targets in cancer through metabolic networks O Folger, L Jerby, C Frezza, E Gottlieb, E Ruppin, T Shlomi Molecular systems biology 7 (1), 501, 2011 | 589 | 2011 |
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase C Frezza, L Zheng, O Folger, KN Rajagopalan, ED MacKenzie, L Jerby, ... Nature 477 (7363), 225-228, 2011 | 548 | 2011 |
Glutamine‐driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia J Fan, JJ Kamphorst, R Mathew, MK Chung, E White, T Shlomi, ... Molecular systems biology 9 (1), 712, 2013 | 462 | 2013 |
Computational reconstruction of tissue‐specific metabolic models: application to human liver metabolism L Jerby, T Shlomi, E Ruppin Molecular systems biology 6 (1), 401, 2010 | 435 | 2010 |
Metabolite concentrations, fluxes and free energies imply efficient enzyme usage JO Park, SA Rubin, YF Xu, D Amador-Noguez, J Fan, T Shlomi, ... Nature chemical biology 12 (7), 482-489, 2016 | 402 | 2016 |
iMAT: an integrative metabolic analysis tool H Zur, E Ruppin, T Shlomi Bioinformatics 26 (24), 3140-3142, 2010 | 345 | 2010 |
A genome‐scale computational study of the interplay between transcriptional regulation and metabolism T Shlomi, Y Eisenberg, R Sharan, E Ruppin Molecular systems biology 3 (1), 101, 2007 | 320 | 2007 |
Transfer of miRNA in macrophage-derived exosomes induces drug resistance in pancreatic adenocarcinoma Y Binenbaum, E Fridman, Z Yaari, N Milman, A Schroeder, G Ben David, ... Cancer research 78 (18), 5287-5299, 2018 | 313 | 2018 |
Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model K Yizhak, T Benyamini, W Liebermeister, E Ruppin, T Shlomi Bioinformatics 26 (12), i255-i260, 2010 | 305 | 2010 |
Reconstruction of Arabidopsis metabolic network models accounting for subcellular compartmentalization and tissue-specificity S Mintz-Oron, S Meir, S Malitsky, E Ruppin, A Aharoni, T Shlomi Proceedings of the National Academy of Sciences 109 (1), 339-344, 2012 | 295 | 2012 |
Predicting metabolic engineering knockout strategies for chemical production: accounting for competing pathways N Tepper, T Shlomi Bioinformatics 26 (4), 536-543, 2010 | 274 | 2010 |
A new ESI-LC/MS approach for comprehensive metabolic profiling of phytocannabinoids in Cannabis P Berman, K Futoran, GM Lewitus, D Mukha, M Benami, T Shlomi, D Meiri Scientific reports 8 (1), 14280, 2018 | 272 | 2018 |
Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect T Shlomi, T Benyamini, E Gottlieb, R Sharan, E Ruppin PLoS computational biology 7 (3), e1002018, 2011 | 272 | 2011 |
Global characterization of in vivo enzyme catalytic rates and their correspondence to in vitro kcat measurements D Davidi, E Noor, W Liebermeister, A Bar-Even, A Flamholz, K Tummler, ... Proceedings of the National Academy of Sciences 113 (12), 3401-3406, 2016 | 257 | 2016 |
QPath: a method for querying pathways in a protein-protein interaction network T Shlomi, D Segal, E Ruppin, R Sharan BMC bioinformatics 7, 1-9, 2006 | 226 | 2006 |