Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ... Cancer discovery 5 (12), 1282-1295, 2015 | 1216 | 2015 |
CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy V Pillai, K Muralidharan, W Meng, A Bagashev, DA Oldridge, J Rosenthal, ... Blood advances 3 (22), 3539-3549, 2019 | 168 | 2019 |
Roles and functions of HIV-1 Tat protein in the CNS: an overview A Bagashev, BE Sawaya Virology journal 10, 1-20, 2013 | 159 | 2013 |
Role of p53 in neurodegenerative diseases JR Chang, M Ghafouri, R Mukerjee, A Bagashev, T Chabrashvili, ... Neurodegenerative Diseases 9 (2), 68-80, 2012 | 153 | 2012 |
Immune dysregulation in severe influenza ML Heltzer, SE Coffin, K Maurer, A Bagashev, Z Zhang, JS Orange, ... Journal of Leucocyte Biology 85 (6), 1036-1043, 2009 | 142 | 2009 |
HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs JR Chang, R Mukerjee, A Bagashev, L Del Valle, T Chabrashvili, ... Journal of Biological Chemistry 286 (47), 41125-41134, 2011 | 91 | 2011 |
Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19 M Asnani, KE Hayer, AS Naqvi, S Zheng, SY Yang, D Oldridge, F Ibrahim, ... Leukemia 34 (4), 1202-1207, 2020 | 80 | 2020 |
CD19 alterations emerging after CD19-directed immunotherapy cause retention of the misfolded protein in the endoplasmic reticulum A Bagashev, E Sotillo, CHA Tang, KL Black, J Perazzelli, SH Seeholzer, ... Molecular and Cellular Biology 38 (21), e00383-18, 2018 | 61 | 2018 |
Aberrant splicing in B-cell acute lymphoblastic leukemia KL Black, AS Naqvi, M Asnani, KE Hayer, SY Yang, E Gillespie, ... Nucleic acids research 46 (21), 11357-11369, 2018 | 57 | 2018 |
Deregulation of microRNAs by HIV-1 Vpr protein leads to the development of neurocognitive disorders R Mukerjee, JR Chang, L Del Valle, A Bagashev, MM Gayed, RB Lyde, ... Journal of Biological Chemistry 286 (40), 34976-34985, 2011 | 48 | 2011 |
Modulation of CD22 protein expression in childhood leukemia by pervasive splicing aberrations: implications for CD22-directed immunotherapies S Zheng, E Gillespie, AS Naqvi, KE Hayer, Z Ang, M Torres-Diz, ... Blood cancer discovery 3 (2), 103-115, 2022 | 35 | 2022 |
Oncogene-independent BCR-like signaling adaptation confers drug resistance in Ph-like ALL C Hurtz, GB Wertheim, JP Loftus, D Blumenthal, A Lehman, Y Li, ... The Journal of clinical investigation 130 (7), 3637-3653, 2020 | 34 | 2020 |
Leucine-rich repeat (in Flightless I) interacting protein-1 regulates a rapid type I interferon response A Bagashev, MC Fitzgerald, DF LaRosa, PP Rose, S Cherry, AC Johnson, ... Journal of Interferon & Cytokine Research 30 (11), 843-852, 2010 | 33 | 2010 |
Noncoding RNAs and LRRFIP1 regulate TNF expression L Shi, L Song, M Fitzgerald, K Maurer, A Bagashev, KE Sullivan The Journal of Immunology 192 (7), 3057-3067, 2014 | 30 | 2014 |
Myeloid differentiation primary response gene 88 (MyD88) deficiency in a large kindred DH Conway, J Dara, A Bagashev, KE Sullivan Journal of allergy and clinical immunology 126 (1), 172-175, 2010 | 30 | 2010 |
HIV-1 Tat protein promotes neuronal dysregulation by inhibiting E2F transcription factor 3 (E2F3) M Santerre, A Bagashev, L Gorecki, KZ Lysek, Y Wang, J Shrestha, ... Journal of Biological Chemistry 294 (10), 3618-3633, 2019 | 29 | 2019 |
Cdk9 phosphorylates Pirh2 protein and prevents degradation of p53 protein A Bagashev, S Fan, R Mukerjee, P Paolo Claudio, T Chabrashvili, ... Cell Cycle 12 (10), 1569-1577, 2013 | 24 | 2013 |
Characterization of LRRFIP1 R Arakawa, A Bagashev, L Song, K Maurer, KE Sullivan Biochemistry and Cell Biology 88 (6), 899-906, 2010 | 24 | 2010 |
Convergence of acquired mutations and alternative splicing of CD19 enables resistance to CART-19 immunotherapy. Cancer Discov 5: 1282–1295 E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ... Nat Med 24, 1504-1506, 2015 | 22 | 2015 |
Combinatorial efficacy of entospletinib and chemotherapy in patient-derived xenograft models of infant acute lymphoblastic leukemia JP Loftus, A Yahiaoui, PA Brown, LM Niswander, A Bagashev, M Wang, ... Haematologica 106 (4), 1067, 2021 | 20 | 2021 |