PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair T Ochi, AN Blackford, J Coates, S Jhujh, S Mehmood, N Tamura, ... Science 347 (6218), 185-188, 2015 | 374 | 2015 |
Systematic E2 screening reveals a UBE2D–RNF138–CtIP axis promoting DNA repair CK Schmidt, Y Galanty, M Sczaniecka-Clift, J Coates, S Jhujh, M Demir, ... Nature cell biology 17 (11), 1458-1470, 2015 | 125 | 2015 |
MDC1 PST-repeat region promotes histone H2AX-independent chromatin association and DNA damage tolerance I Salguero, R Belotserkovskaya, J Coates, M Sczaniecka-Clift, M Demir, ... Nature communications 10 (1), 5191, 2019 | 44 | 2019 |
Cancer-associated SF3B1 mutations confer a BRCA-like cellular phenotype and synthetic lethality to PARP inhibitors KM Lappin, EM Barros, SS Jhujh, GW Irwin, H McMillan, FG Liberante, ... Cancer research 82 (5), 819-830, 2022 | 32 | 2022 |
RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1 B Abu-Libdeh, SS Jhujh, S Dhar, JA Sommers, A Datta, GMC Longo, ... The Journal of clinical investigation 132 (5), 2022 | 29 | 2022 |
Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy LJ Grange, JJ Reynolds, F Ullah, B Isidor, RF Shearer, X Latypova, ... Nature communications 13 (1), 6664, 2022 | 26 | 2022 |
The structural mechanism of dimeric DONSON in replicative helicase activation MA Cvetkovic, P Passaretti, A Butryn, A Reynolds-Winczura, G Kingsley, ... Molecular Cell 83 (22), 4017-4031. e9, 2023 | 21 | 2023 |
STAG2 loss gives rise to therapeutically targetable DNA damage repair defects and altered replication fork dynamics in acute myeloid leukaemia HE Black, S Jhujh, GS Stewart, KI Savage, KI Mills Blood 134, 1255, 2019 | 4 | 2019 |
Discovery of a new hereditary RECQ helicase disorder RECON syndrome positions the replication stress response and genome homeostasis as centrally important processes in aging … A Datta, JA Sommers, SS Jhujh, T Harel, GS Stewart, RM Brosh Jr Ageing research reviews 86, 101887, 2023 | 2 | 2023 |
The Promotion of Genomic Instability in Human Fibroblasts by Adenovirus 12 Early Region 1B 55K Protein in the Absence of Viral Infection T Abualfaraj, NC Hagkarim, R Hollingworth, L Grange, S Jhujh, ... Viruses 13 (12), 2444, 2021 | 1 | 2021 |
E3 ligases: a ubiquitous link between DNA repair, DNA replication and human disease AS Chauhan, SS Jhujh, GS Stewart Biochemical Journal 481 (14), 923-944, 2024 | | 2024 |
USP37 prevents premature disassembly of stressed replisomes by TRAIP OV Kochenova, G D’Alessandro, D Pilger, E Schmid, SL Richards, ... bioRxiv, 2024 | | 2024 |
Research data supporting" Systematic E2 screening reveals a UBE2D–RNF138–CtIP axis promoting DNA repair" CK Schmidt, Y Galanty, M Sczaniecka-Clift, J Coates, S Jhujh, M Demir, ... | | 2015 |