Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites AN Thorburn, CI McKenzie, S Shen, D Stanley, L Macia, LJ Mason, ... Nature communications 6, 7320, 2015 | 857 | 2015 |
Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype AG Uren, L Wong, M Pakusch, KJ Fowler, FJ Burrows, DL Vaux, ... Current Biology 10 (21), 1319-1328, 2000 | 734 | 2000 |
Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes E Mariño, JL Richards, KH McLeod, D Stanley, ... Nature Immunology 18, 552-562, 2017 | 642 | 2017 |
ATRX interacts with H3. 3 in maintaining telomere structural integrity in pluripotent embryonic stem cells LH Wong, JD McGhie, M Sim, MA Anderson, S Ahn, RD Hannan, ... Genome research 20 (3), 351-360, 2010 | 448 | 2010 |
Neocentromeres: new insights into centromere structure, disease development, and karyotype evolution OJ Marshall, AC Chueh, LH Wong, KHA Choo The American Journal of Human Genetics 82 (2), 261-282, 2008 | 411 | 2008 |
Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere LH Wong, KH Brettingham-Moore, L Chan, JM Quach, MA Anderson, ... Genome research 17 (8), 1146-1160, 2007 | 336 | 2007 |
Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3γ LH Wong, KG Krauer, I Hatzinisiriou, MJ Estcourt, P Hersey, ND Tam, ... Journal of Biological Chemistry 272 (45), 28779-28785, 1997 | 322 | 1997 |
Active transcription and essential role of RNA polymerase II at the centromere during mitosis FL Chan, OJ Marshall, R Saffery, BO Won Kim, E Earle, KHA Choo, ... Proceedings of the National Academy of Sciences 109 (6), 1979-1984, 2012 | 292 | 2012 |
Human centromere repositioning “in progress” DJ Amor, K Bentley, J Ryan, J Perry, L Wong, H Slater, KHA Choo Proceedings of the national academy of sciences 101 (17), 6542-6547, 2004 | 261 | 2004 |
UBF levels determine the number of active ribosomal RNA genes in mammals E Sanij, G Poortinga, K Sharkey, S Hung, TP Holloway, J Quin, E Robb, ... The Journal of cell biology 183 (7), 1259-1274, 2008 | 249 | 2008 |
The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN‐alpha signals. S Gupta, H Yan, LH Wong, S Ralph, J Krolewski, C Schindler The EMBO journal 15 (5), 1075-1084, 1996 | 226 | 1996 |
Histone H3. 3 incorporation provides a unique and functionally essential telomeric chromatin in embryonic stem cells LH Wong, H Ren, E Williams, J McGhie, S Ahn, M Sim, A Tam, E Earle, ... Genome research 19 (3), 404-414, 2009 | 188 | 2009 |
LINE retrotransposon RNA is an essential structural and functional epigenetic component of a core neocentromeric chromatin AC Chueh, EL Northrop, KH Brettingham-Moore, KHA Choo, LH Wong PLoS Genetics 5 (1), e1000354, 2009 | 188 | 2009 |
Transcription within a functional human centromere R Saffery, H Sumer, S Hassan, LH Wong, JM Craig, K Todokoro, ... Molecular cell 12 (2), 509-516, 2003 | 177 | 2003 |
Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly (ADP-ribose) polymerase-1 protein and are poly (ADP-ribosyl) ated A Saxena, R Saffery, LH Wong, P Kalitsis, KHA Choo Journal of Biological Chemistry 277 (30), 26921-26926, 2002 | 160 | 2002 |
Histone variant H3. 3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres M Udugama, FT M. Chang, FL Chan, MC Tang, HA Pickett, JD R. McGhie, ... Nucleic acids research 43 (21), 10227-10237, 2015 | 130 | 2015 |
New players in heterochromatin silencing: histone variant H3. 3 and the ATRX/DAXX chaperone HPJ Voon, LH Wong Nucleic acids research 44 (4), 1496-1501, 2016 | 123 | 2016 |
Poly (ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc A Saxena, LH Wong, P Kalitsis, E Earle, LG Shaffer, KHA Choo Human molecular genetics 11 (19), 2319-2329, 2002 | 122 | 2002 |
Contribution of the two genes encoding histone variant h3. 3 to viability and fertility in mice MCW Tang, SA Jacobs, DM Mattiske, YM Soh, AN Graham, A Tran, ... PLoS genetics 11 (2), e1004964, 2015 | 121 | 2015 |
Evolutionary dynamics of transposable elements at the centromere LH Wong, KHA Choo TRENDS in Genetics 20 (12), 611-616, 2004 | 121 | 2004 |