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Aldo Di Leonardo
Aldo Di Leonardo
Professor of Genetics, Dept STEBICEF, University of Palermo, Italy.
在 unipa.it 的电子邮件经过验证
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引用次数
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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.
A Di Leonardo, SP Linke, K Clarkin, GM Wahl
Genes & development 8 (21), 2540-2551, 1994
15901994
A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.
SP Linke, KC Clarkin, A Di Leonardo, A Tsou, GM Wahl
Genes & development 10 (8), 934-947, 1996
7091996
DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function
AD Leonardo, SH Khan, SP Linke, V Greco, G Seidita, GM Wahl
Cancer research 57 (6), 1013-1019, 1997
2821997
CENPA overexpression promotes genome instability in pRb-depleted human cells
A Amato, T Schillaci, L Lentini, A Di Leonardo
Molecular cancer 8, 1-14, 2009
1502009
The mitotic kinase Aurora-A promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα+ breast cancer cells
AB D'assoro, C Quatraro, A Amato, M Opyrchal, A Leontovich, Y Ikeda, ...
Oncogene 33 (5), 599-610, 2014
1442014
RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts
F Iovino, L Lentini, A Amato, A Di Leonardo
Molecular cancer 5, 1-11, 2006
1072006
Toward a rationale for the PTC124 (Ataluren) promoted readthrough of premature stop codons: a computational approach and GFP-reporter cell-based assay
L Lentini, R Melfi, A Di Leonardo, A Spinello, G Barone, A Pace, ...
Molecular pharmaceutics 11 (3), 653-664, 2014
992014
NOTCH3 expression is linked to breast cancer seeding and distant metastasis
AA Leontovich, M Jalalirad, JL Salisbury, L Mills, C Haddox, M Schroeder, ...
Breast Cancer Research 20, 1-19, 2018
752018
Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype
L Lentini, A Amato, T Schillaci, A Di Leonardo
BMC cancer 7, 1-13, 2007
692007
Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives
I Pibiri, L Lentini, R Melfi, G Gallucci, A Pace, A Spinello, G Barone, ...
European journal of medicinal chemistry 101, 236-244, 2015
632015
RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation
A Amato, L Lentini, T Schillaci, F Iovino, A Di Leonardo
BMC cell biology 10, 1-13, 2009
592009
MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a p53 pathway preventing aneuploid cells propagation
L Lentini, V Barra, T Schillaci, A Di Leonardo
Journal of cellular physiology 227 (9), 3324-3332, 2012
452012
Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs)
A Campofelice, L Lentini, A Di Leonardo, R Melfi, M Tutone, A Pace, ...
International journal of molecular sciences 20 (13), 3329, 2019
422019
Retinoblastoma epidemiology: does the evidence matter?
D Mastrangelo, S De Francesco, A Di Leonardo, L Lentini, ...
European Journal of Cancer 43 (10), 1596-1603, 2007
422007
Expression of the kinetochore protein Hec1 during the cell cycle in normal and cancer cells and its regulation by the pRb pathway
C Ferretti, P Totta, M Fiore, M Mattiuzzo, T Schillaci, R Ricordye, ...
Cell Cycle 9 (20), 4174-4182, 2010
412010
Bypass of cell cycle arrest induced by transient DNMT1 post-transcriptional silencing triggers aneuploidy in human cells
V Barra, T Schillaci, L Lentini, G Costa, A Di Leonardo
Cell division 7, 1-12, 2012
372012
Exploring the readthrough of nonsense mutations by non-acidic Ataluren analogues selected by ligand-based virtual screening
I Pibiri, L Lentini, M Tutone, R Melfi, A Pace, A Di Leonardo
European Journal of Medicinal Chemistry 122, 429-435, 2016
362016
DNA demethylation caused by 5-Aza-2′-deoxycytidine induces mitotic alterations and aneuploidy
G Costa, V Barra, L Lentini, D Cilluffo, A Di Leonardo
Oncotarget 7 (4), 3726, 2016
342016
Cell cycle regulation of gene amplification
A Di Leonardo, SP Linke, Y Yin, GM Wahl
Cold Spring Harbor Symposia on Quantitative Biology 58, 655-667, 1993
341993
Rescuing the CFTR protein function: Introducing 1, 3, 4-oxadiazoles as translational readthrough inducing drugs
I Pibiri, L Lentini, R Melfi, M Tutone, S Baldassano, PR Galluzzo, ...
European journal of medicinal chemistry 159, 126-142, 2018
332018
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