Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis TD Warner, F Giuliano, I Vojnovic, A Bukasa, JA Mitchell, JR Vane Proceedings of the National Academy of Sciences 96 (13), 7563-7568, 1999 | 2006 | 1999 |
Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor. G De Nucci, R Thomas, P D'Orleans-Juste, E Antunes, C Walder, ... Proceedings of the National Academy of Sciences 85 (24), 9797-9800, 1988 | 1824 | 1988 |
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. JS Pollock, U Förstermann, JA Mitchell, TD Warner, HH Schmidt, ... Proceedings of the National Academy of Sciences 88 (23), 10480-10484, 1991 | 1254 | 1991 |
Isoforms of nitric oxide synthase characterization and purification from different cell types U Förstermann, HHHW Schmidt, JS Pollock, H Sheng, JA Mitchell, ... Biochemical pharmacology 42 (10), 1849-1857, 1991 | 1156 | 1991 |
Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic TD Warner, JA Mitchell The FASEB journal 18 (7), 790-804, 2004 | 958 | 2004 |
Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides HHHW Schmidt, TD Warner, K Ishii, H Sheng, FF Murad Science 255 (5045), 721-723, 1992 | 539 | 1992 |
Cyclooxygenase-3 (COX-3): filling in the gaps toward a COX continuum? TD Warner, JA Mitchell Proceedings of the National Academy of Sciences 99 (21), 13371-13373, 2002 | 467 | 2002 |
Cyclo‐oxygenase‐2: pharmacology, physiology, biochemistry and relevance to NSAID therapy JA Mitchell, TD Warner British journal of pharmacology 128 (6), 1121-1132, 1999 | 454 | 1999 |
Circulating microRNAs as novel biomarkers for platelet activation P Willeit, A Zampetaki, K Dudek, D Kaudewitz, A King, NS Kirkby, ... Circulation research 112 (4), 595-600, 2013 | 444 | 2013 |
Co‐induction of nitric oxide synthase and cyclo‐oxygenase: interactions between nitric oxide and prostanoids TA Swierkosz, JA Mitchell, TD Warner, RM Botting, JR Vane British journal of pharmacology 114 (7), 1335-1342, 1995 | 412 | 1995 |
Endothelin-1 and endothelin-3 release EDRF from isolated perfused arterial vessels of the rat and rabbit TD Warner, JA Mitchell, G de Nucci, JR Vane Journal of cardiovascular pharmacology 13, S85-88, 1989 | 383 | 1989 |
Interpreting the clinical significance of the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2 P Brooks, P Emery, JF Evans, H Fenner, CJ Hawkey, C Patrono, J Smolen, ... Rheumatology 38 (8), 779-788, 1999 | 376 | 1999 |
Receptor-mediated release of endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells is coupled. G De Nucci, RJ Gryglewski, TD Warner, JR Vane Proceedings of the National Academy of Sciences 85 (7), 2334-2338, 1988 | 350 | 1988 |
COX isoforms in the cardiovascular system: understanding the activities of non-steroidal anti-inflammatory drugs JA Mitchell, TD Warner Nature reviews Drug discovery 5 (1), 75-86, 2006 | 339 | 2006 |
Effects of low-dose aspirin on acute inflammatory responses in humans T Morris, M Stables, A Hobbs, P de Souza, P Colville-Nash, T Warner, ... The Journal of Immunology 183 (3), 2089-2096, 2009 | 335 | 2009 |
Regulation and subcellular location of nitrogen oxide synthases in RAW264. 7 macrophages. HH Schmidt, TD Warner, M Nakane, U Förstermann, F Murad Molecular pharmacology 41 (4), 615-624, 1992 | 330 | 1992 |
Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat TD Warner, G de Nucci, JR Vane European journal of pharmacology 159 (3), 325-326, 1989 | 324 | 1989 |
Sputum and plasma endothelin-1 levels in exacerbations of chronic obstructive pulmonary disease M Roland, A Bhowmik, RJ Sapsford, TAR Seemungal, DJ Jeffries, ... Thorax 56 (1), 30-35, 2001 | 319 | 2001 |
Activation of PPARβ/δ induces endothelial cell proliferation and angiogenesis L Piqueras, AR Reynolds, KM Hodivala-Dilke, A Alfranca, JM Redondo, ... Arteriosclerosis, thrombosis, and vascular biology 27 (1), 63-69, 2007 | 310 | 2007 |
Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure CJ Reynolds, C Pade, JM Gibbons, AD Otter, KM Lin, D Muñoz Sandoval, ... Science 377 (6603), eabq1841, 2022 | 297 | 2022 |