| Ustekinumab as induction and maintenance therapy for Crohn’s disease BG Feagan, WJ Sandborn, C Gasink, D Jacobstein, Y Lang, JR Friedman, ... New England journal of medicine 375 (20), 1946-1960, 2016 | 1773 | 2016 |
| KAP-1, a novel corepressor for the highly conserved KRAB repression domain. JR Friedman, WJ Fredericks, DE Jensen, DW Speicher, XP Huang, ... Genes & development 10 (16), 2067-2078, 1996 | 806 | 1996 |
| Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria GF Sonnenberg, LA Monticelli, T Alenghat, TC Fung, NA Hutnick, ... Science 336 (6086), 1321-1325, 2012 | 803 | 2012 |
| Krüppel-associated boxes are potent transcriptional repression domains. JF Margolin, JR Friedman, WK Meyer, H Vissing, HJ Thiesen, ... Proceedings of the National Academy of Sciences 91 (10), 4509-4513, 1994 | 773 | 1994 |
| The initiation of liver development is dependent on Foxa transcription factors CS Lee, JR Friedman, JT Fulmer, KH Kaestner Nature 435 (7044), 944-947, 2005 | 675 | 2005 |
| Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2α … DC Schultz, JR Friedman, FJ Rauscher Genes & development 15 (4), 428-443, 2001 | 663 | 2001 |
| Single-cell analysis of Crohn’s disease lesions identifies a pathogenic cellular module associated with resistance to anti-TNF therapy JC Martin, C Chang, G Boschetti, R Ungaro, M Giri, JA Grout, K Gettler, ... Cell 178 (6), 1493-1508. e20, 2019 | 629 | 2019 |
| The Foxa family of transcription factors in development and metabolism JR Friedman, KH Kaestner Cellular and Molecular Life Sciences CMLS 63, 2317-2328, 2006 | 590 | 2006 |
| KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box–zinc finger proteins in … RF Ryan, DC Schultz, K Ayyanathan, PB Singh, JR Friedman, ... Molecular and cellular biology, 1999 | 483 | 1999 |
| MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function LB McKenna, J Schug, A Vourekas, JB McKenna, NC Bramswig, ... Gastroenterology 139 (5), 1654-1664. e1, 2010 | 370 | 2010 |
| Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets V Kameswaran, NC Bramswig, LB McKenna, M Penn, J Schug, NJ Hand, ... Cell metabolism 19 (1), 135-145, 2014 | 365 | 2014 |
| Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development N Gao, J LeLay, MZ Vatamaniuk, S Rieck, JR Friedman, KH Kaestner Genes & development 22 (24), 3435-3448, 2008 | 356 | 2008 |
| Glucocorticoid receptor-dependent gene regulatory networks P Phuc Le, JR Friedman, J Schug, JE Brestelli, JB Parker, IM Bochkis, ... PLoS genetics 1 (2), e16, 2005 | 288 | 2005 |
| Liver development Y Zong, JR Friedman Liver disease in children, 1-813, 2014 | 279 | 2014 |
| Reconstitution of the KRAB-KAP-1 repressor complex: a model system for defining the molecular anatomy of RING-B box-coiled-coil domain-mediated protein-protein interactions H Peng, GE Begg, DC Schultz, JR Friedman, DE Jensen, DW Speicher, ... Journal of molecular biology 295 (5), 1139-1162, 2000 | 267 | 2000 |
| A functional genomics predictive network model identifies regulators of inflammatory bowel disease LA Peters, J Perrigoue, A Mortha, A Iuga, W Song, EM Neiman, ... Nature genetics 49 (10), 1437-1449, 2017 | 242 | 2017 |
| Foxa2 regulates multiple pathways of insulin secretion KA Lantz, MZ Vatamaniuk, JE Brestelli, JR Friedman, FM Matschinsky, ... The Journal of clinical investigation 114 (4), 512-520, 2004 | 223 | 2004 |
| Circulating microRNA is a biomarker of pediatric Crohn disease AM Zahm, M Thayu, NJ Hand, A Horner, MB Leonard, JR Friedman Journal of pediatric gastroenterology and nutrition 53 (1), 26-33, 2011 | 209 | 2011 |
| Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress IM Bochkis, NE Rubins, P White, EE Furth, JR Friedman, KH Kaestner Nature medicine 14 (8), 828-836, 2008 | 206 | 2008 |
| Gut microbiota density influences host physiology and is shaped by host and microbial factors EJ Contijoch, GJ Britton, C Yang, I Mogno, Z Li, R Ng, SR Llewellyn, ... Elife 8, e40553, 2019 | 169 | 2019 |
