Type 2 diabetes as an inflammatory disease MY Donath, SE Shoelson Nature reviews immunology 11 (2), 98-107, 2011 | 4121 | 2011 |
Interleukin-1–receptor antagonist in type 2 diabetes mellitus CM Larsen, M Faulenbach, A Vaag, A Vølund, JA Ehses, B Seifert, ... New England Journal of Medicine 356 (15), 1517-1526, 2007 | 2153 | 2007 |
Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets K Maedler, P Sergeev, F Ris, J Oberholzer, HI Joller-Jemelka, GA Spinas, ... The Journal of clinical investigation 110 (6), 851-860, 2002 | 1692 | 2002 |
Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo … PM Ridker, JG MacFadyen, T Thuren, BM Everett, P Libby, RJ Glynn, ... The Lancet 390 (10105), 1833-1842, 2017 | 1217 | 2017 |
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells H Ellingsgaard, I Hauselmann, B Schuler, AM Habib, LL Baggio, DT Meier, ... Nature medicine 17 (11), 1481-1489, 2011 | 1009 | 2011 |
Increased number of islet-associated macrophages in type 2 diabetes JA Ehses, A Perren, E Eppler, P Ribaux, JA Pospisilik, R Maor-Cahn, ... Diabetes 56 (9), 2356-2370, 2007 | 908 | 2007 |
Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled … PM Ridker, JG MacFadyen, BM Everett, P Libby, T Thuren, RJ Glynn, ... The Lancet 391 (10118), 319-328, 2018 | 815 | 2018 |
Targeting inflammation in the treatment of type 2 diabetes: time to start MY Donath Nature reviews Drug discovery 13 (6), 465-476, 2014 | 778 | 2014 |
Distinct effects of saturated and monounsaturated fatty acids on β-cell turnover and function K Maedler, GA Spinas, D Dyntar, W Moritz, N Kaiser, MY Donath Diabetes 50 (1), 69-76, 2001 | 775 | 2001 |
Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic β-cell turnover and function K Maedler, J Oberholzer, P Bucher, GA Spinas, MY Donath Diabetes 52 (3), 726-733, 2003 | 740 | 2003 |
Inflammation in obesity, diabetes, and related disorders TV Rohm, DT Meier, JM Olefsky, MY Donath Immunity 55 (1), 31-55, 2022 | 727 | 2022 |
A guiding map for inflammation MG Netea, F Balkwill, M Chonchol, F Cominelli, MY Donath, ... Nature immunology 18 (8), 826-831, 2017 | 690 | 2017 |
Inflammatory mediators and islet β-cell failure: a link between type 1 and type 2 diabetes MY Donath, J Størling, K Maedler, T Mandrup-Poulsen Journal of molecular medicine 81, 455-470, 2003 | 649 | 2003 |
Mechanisms of β-cell death in type 2 diabetes MY Donath, JA Ehses, K Maedler, DM Schumann, H Ellingsgaard, ... Diabetes 54 (suppl_2), S108-S113, 2005 | 616 | 2005 |
Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes. MY Donath, DJ Gross, E Cerasi, N Kaiser Diabetes 48 (4), 738-744, 1999 | 606 | 1999 |
Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications MY Donath, PA Halban Diabetologia 47, 581-589, 2004 | 580 | 2004 |
Glucose induces β-cell apoptosis via upregulation of the Fas receptor in human islets K Maedler, GA Spinas, R Lehmann, P Sergeev, M Weber, A Fontana, ... diabetes 50 (8), 1683-1690, 2001 | 543 | 2001 |
Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes CM Larsen, M Faulenbach, A Vaag, JA Ehses, MY Donath, ... Diabetes care 32 (9), 1663-1668, 2009 | 483 | 2009 |
Sulfonylurea induced β-cell apoptosis in cultured human islets K Maedler, RD Carr, D Bosco, RA Zuellig, T Berney, MY Donath The Journal of Clinical Endocrinology & Metabolism 90 (1), 501-506, 2005 | 482 | 2005 |
Islet inflammation impairs the pancreatic β-cell in type 2 diabetes MY Donath, M Böni-Schnetzler, H Ellingsgaard, JA Ehses Physiology 24 (6), 325-331, 2009 | 444 | 2009 |