受强制性开放获取政策约束的文章 - Guillaume Lessene了解详情
无法在其他位置公开访问的文章：11 篇
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
A Kotschy, Z Szlavik, J Murray, J Davidson, AL Maragno, ...
Nature 538 (7626), 477-482, 2016
强制性开放获取政策： National Health and Medical Research Council, Australia
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis
K McArthur, LW Whitehead, JM Heddleston, L Li, BS Padman, V Oorschot, ...
Science 359 (6378), eaao6047, 2018
强制性开放获取政策： Howard Hughes Medical Institute, Gordon and Betty Moore Foundation …
The manipulation of apoptosis for cancer therapy using BH3-mimetic drugs
ST Diepstraten, MA Anderson, PE Czabotar, G Lessene, A Strasser, ...
Nature Reviews Cancer 22 (1), 45-64, 2022
强制性开放获取政策： National Health and Medical Research Council, Australia
Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1
TC Teh, NY Nguyen, DM Moujalled, D Segal, G Pomilio, S Rijal, ...
Leukemia 32 (2), 303-312, 2018
强制性开放获取政策： National Health and Medical Research Council, Australia
Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL
JM Murphy, IS Lucet, JM Hildebrand, MC Tanzer, SN Young, P Sharma, ...
Biochemical Journal 457 (3), 369-377, 2014
强制性开放获取政策： Australian Research Council, National Health and Medical Research Council …
Potent inhibition of necroptosis by simultaneously targeting multiple effectors of the pathway
CL Pierotti, MC Tanzer, AV Jacobsen, JM Hildebrand, JM Garnier, ...
ACS Chemical Biology 15 (10), 2702-2713, 2020
强制性开放获取政策： National Health and Medical Research Council, Australia
Small molecules targeting Mcl-1: the search for a silver bullet in cancer therapy
D Nhu, G Lessene, DCS Huang, CJ Burns
MedChemComm 7 (5), 778-787, 2016
强制性开放获取政策： National Health and Medical Research Council, Australia
Exploiting the Biginelli reaction: nitrogen-rich pyrimidine-based tercyclic α-helix mimetics
Z Lim, PJ Duggan, S San Wan, G Lessene, AG Meyer, KL Tuck
Tetrahedron 72 (9), 1151-1160, 2016
强制性开放获取政策： National Health and Medical Research Council, Australia
Strategies, Setbacks, and Successes in the Synthesis of (−)-Spiroleucettadine
RA Lamb, NT Lucas, G Lessene, BC Hawkins
The Journal of Organic Chemistry 83 (17), 10120-10133, 2018
强制性开放获取政策： National Health and Medical Research Council, Australia
Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-XL and BCL-2
MJ Roy, A Vom, T Okamoto, BJ Smith, RW Birkinshaw, H Yang, H Abdo, ...
Journal of Medicinal Chemistry 64 (9), 5447-5469, 2021
强制性开放获取政策： Australian Research Council, National Health and Medical Research Council …
Targeting cell death pathways with small molecules: playing with life and death at the cellular level to treat diseases
G Lessene
Future Medicinal Chemistry 7 (16), 2099-2102, 2015
强制性开放获取政策： National Health and Medical Research Council, Australia
可在其他位置公开访问的文章：65 篇
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
PE Czabotar, G Lessene, A Strasser, JM Adams
Nature reviews Molecular cell biology 15 (1), 49-63, 2014
强制性开放获取政策： Australian Research Council, National Health and Medical Research Council …
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production
MJ White, K McArthur, D Metcalf, RM Lane, JC Cambier, MJ Herold, ...
Cell 159 (7), 1549-1562, 2014
强制性开放获取政策： US National Institutes of Health, National Health and Medical Research …
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ...
Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014
强制性开放获取政策： Australian Research Council, National Health and Medical Research Council …
Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2
T Klemm, G Ebert, DJ Calleja, CC Allison, LW Richardson, JP Bernardini, ...
The EMBO journal 39 (18), e106275, 2020
强制性开放获取政策： National Health and Medical Research Council, Australia, Netherlands …
Structure-guided design of a selective BCL-XL inhibitor
G Lessene, PE Czabotar, BE Sleebs, K Zobel, KN Lowes, JM Adams, ...
Nature chemical biology 9 (6), 390-397, 2013
强制性开放获取政策： Australian Research Council, National Health and Medical Research Council …
Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity
ZF Tao, L Hasvold, L Wang, X Wang, AM Petros, CH Park, ER Boghaert, ...
ACS medicinal chemistry letters 5 (10), 1088-1093, 2014
强制性开放获取政策： Australian Research Council, National Health and Medical Research Council …
BH3-mimetic drugs: blazing the trail for new cancer medicines
D Merino, GL Kelly, G Lessene, AH Wei, AW Roberts, A Strasser
Cancer cell 34 (6), 879-891, 2018
强制性开放获取政策： National Health and Medical Research Council, Australia, Medical Research …
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
AL Samson, Y Zhang, ND Geoghegan, XJ Gavin, KA Davies, ...
Nature communications 11 (1), 3151, 2020
强制性开放获取政策： US National Science Foundation, Howard Hughes Medical Institute, National …
The mitochondrial apoptotic effectors BAX/BAK activate caspase-3 and-7 to trigger NLRP3 inflammasome and caspase-8 driven IL-1β activation
JE Vince, D De Nardo, W Gao, AJ Vince, C Hall, K McArthur, D Simpson, ...
Cell reports 25 (9), 2339-2353. e4, 2018
强制性开放获取政策： Howard Hughes Medical Institute, Wellcome Trust
出版信息和资助信息由计算机程序自动确定