Discovery of potent human glutaminyl cyclase inhibitors as anti-Alzheimer’s agents based on rational design VH Hoang, PT Tran, M Cui, VTH Ngo, J Ann, J Park, J Lee, K Choi, H Cho, ... Journal of medicinal chemistry 60 (6), 2573-2590, 2017 | 44 | 2017 |
Structure Activity Relationship of Human Glutaminyl Cyclase Inhibitors Having an N-(5-Methyl-1H-imidazol-1-yl) propyl Thiourea Template PT Tran, VH Hoang, SA Thorat, SE Kim, J Ann, YJ Chang, DW Nam, ... Bioorganic & medicinal chemistry, 2013 | 40 | 2013 |
Emerging role of circulating tumor cells in gastric cancer P Thanh Huong, S Gurshaney, N Thanh Binh, A Gia Pham, ... Cancers 12 (3), 695, 2020 | 39 | 2020 |
Prediction of AChE-ligand affinity using the umbrella sampling simulation NT Lan, KB Vu, MKD Ngoc, PT Tran, DM Hiep, NT Tung, ST Ngo Journal of Molecular Graphics and Modelling 93, 107441, 2019 | 28 | 2019 |
TRPV1 antagonist with high analgesic efficacy: 2-Thio pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl) propanamides TH Ha, HC Ryu, SE Kim, HS Kim, J Ann, PT Tran, VH Hoang, K Son, ... Bioorganic & medicinal chemistry 21 (21), 6657-6664, 2013 | 27 | 2013 |
Inhibitory effects of compounds from Styrax obassia on NO production TQ Cao, MH Tran, JA Kim, PT Tran, JH Lee, MH Woo, HK Lee, BS Min Bioorganic & Medicinal Chemistry Letters 25 (22), 5087-5091, 2015 | 26 | 2015 |
Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer’s agents: Structure-activity relationship study of Arg-mimetic region VTH Ngo, VH Hoang, PT Tran, J Ann, M Cui, G Park, S Choi, J Lee, H Kim, ... Bioorganic & medicinal chemistry 26 (5), 1035-1049, 2018 | 23 | 2018 |
Novel 3, 4-dihydro-4-oxoquinazoline-based acetohydrazides: Design, synthesis and evaluation of antitumor cytotoxicity and caspase activation activity PT Tran, CV Phuong, PH Duc, DT Anh, PT Hai, NT Thuan, HJ Lee, ... Bioorganic Chemistry 92, 103202, 2019 | 22 | 2019 |
Structure-activity relationship investigation of Phe-Arg mimetic region of human glutaminyl cyclase inhibitors VTH Ngo, VH Hoang, PT Tran, N Van Manh, J Ann, E Kim, M Cui, S Choi, ... Bioorganic & Medicinal Chemistry 26 (12), 3133-3144, 2018 | 21 | 2018 |
Discovery of conformationally restricted human glutaminyl cyclase inhibitors as potent anti-Alzheimer’s agents by structure-based design VH Hoang, VTH Ngo, M Cui, NV Manh, PT Tran, J Ann, HJ Ha, H Kim, ... Journal of medicinal chemistry 62 (17), 8011-8027, 2019 | 20 | 2019 |
(E)-N'-Arylidene-2-(4-oxoquinazolin-4(3H)-yl) acetohydrazides: Synthesis and evaluation of antitumor cytotoxicity and caspase activation activity LC Huan, CV Phuong, LC Truc, VN Thanh, H Pham-The, LTT Huong, ... Journal of Enzyme Inhibition and Medicinal Chemistry 34 (1), 465-478, 2019 | 20 | 2019 |
Impact of the Astaxanthin, Betanin, and EGCG Compounds on Small Oligomers of Amyloid Aβ40 Peptide H Minh Hung, MT Nguyen, PT Tran, VK Truong, J Chapman, ... Journal of Chemical Information and Modeling 60 (3), 1399-1408, 2020 | 19 | 2020 |
2-Aryl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl) propanamides as highly potent TRPV1 antagonists HC Ryu, S Seo, MS Kim, MY Kim, HS Kim, J Ann, PT Tran, VH Hoang, ... Bioorganic & medicinal chemistry letters 24 (16), 4044-4047, 2014 | 19 | 2014 |
Discovery of leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors S Yoon, JH Kim, SE Kim, C Kim, PT Tran, J Ann, Y Koh, J Jang, S Kim, ... Journal of Medicinal Chemistry 59 (22), 10322-10328, 2016 | 18 | 2016 |
Identifying possible AChE inhibitors from drug-like molecules via machine learning and experimental studies TH Nguyen, PT Tran, NQA Pham, VH Hoang, DM Hiep, ST Ngo ACS omega 7 (24), 20673-20682, 2022 | 16 | 2022 |
In vitro and in silico determination of glutaminyl cyclase inhibitors PT Tran, VH Hoang, J Lee, TTT Hien, NT Tung, ST Ngo RSC advances 9 (51), 29619-29627, 2019 | 16 | 2019 |
Inhibition of glutaminyl cyclase ameliorates amyloid pathology in an animal model of Alzheimer's disease via the modulation of γ-secretase activity H Song, YJ Chang, M Moon, SK Park, PT Tran, VH Hoang, J Lee, ... Journal of Alzheimer's Disease 43 (3), 797-807, 2015 | 16 | 2015 |
Discovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors S Yoon, JH Kim, Y Koh, PT Tran, J Ann, I Yoon, J Jang, WK Kim, S Lee, ... Bioorganic & Medicinal Chemistry 25 (15), 4145-4152, 2017 | 15 | 2017 |
Impact of aluminum chloride on process performance and microbial community structure of granular sludge in an upflow anaerobic sludge blanket reactor for natural rubber … NT Thanh, T Watari, TP Thao, M Hatamoto, D Tanikawa, K Syutsubo, ... Water Science and Technology 74 (2), 500-507, 2016 | 15 | 2016 |
Anti-inflammatory effects of alkaloid enriched extract from roots of Eurycoma longifolia Jack DTT Hien, TP Long, TP Thao, JH Lee, DT Trang, NTT Minh, P Van Cuong, ... Asian Pacific Journal of Tropical Biomedicine 9 (1), 18-23, 2019 | 14 | 2019 |