| An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex Y Zhang, K Chen, SA Sloan, ML Bennett, AR Scholze, S O'Keeffe, ... Journal of neuroscience 34 (36), 11929-11947, 2014 | 4752 | 2014 |
| A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome M Sultan, MH Schulz, H Richard, A Magen, A Klingenhoff, M Scherf, ... Science 321 (5891), 956-960, 2008 | 1580 | 2008 |
| A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model IM Chiu, ETA Morimoto, H Goodarzi, JT Liao, S O’Keeffe, HP Phatnani, ... Cell reports 4 (2), 385-401, 2013 | 665 | 2013 |
| Exome sequencing and characterization of 49,960 individuals in the UK Biobank CV Van Hout, I Tachmazidou, JD Backman, JD Hoffman, D Liu, ... Nature 586 (7831), 749-756, 2020 | 408 | 2020 |
| X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes H Hu, SA Haas, J Chelly, H Van Esch, M Raynaud, APM de Brouwer, ... Molecular psychiatry 21 (1), 133-148, 2016 | 311 | 2016 |
| Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations CG Boer, K Hatzikotoulas, L Southam, L Stefánsdóttir, Y Zhang, ... Cell 184 (18), 4784-4818. e17, 2021 | 307 | 2021 |
| Accelerated high-yield generation of limb-innervating motor neurons from human stem cells MW Amoroso, GF Croft, DJ Williams, S O'Keeffe, MA Carrasco, AR Davis, ... Journal of Neuroscience 33 (2), 574-586, 2013 | 297 | 2013 |
| Transcription factor binding predictions using TRAP for the analysis of ChIP-seq data and regulatory SNPs M Thomas-Chollier, A Hufton, M Heinig, S O'keeffe, NE Masri, HG Roider, ... Nature protocols 6 (12), 1860-1869, 2011 | 245 | 2011 |
| Sour sensing from the tongue to the brain J Zhang, H Jin, W Zhang, C Ding, S O’Keeffe, M Ye, CS Zuker Cell 179 (2), 392-402. e15, 2019 | 201 | 2019 |
| The extracellular leucine-rich repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns J Dolan, K Walshe, S Alsbury, K Hokamp, S O'Keeffe, T Okafuji, ... BMC genomics 8, 1-24, 2007 | 194 | 2007 |
| PASTAA: identifying transcription factors associated with sets of co-regulated genes HG Roider, T Manke, S O'Keeffe, M Vingron, SA Haas Bioinformatics 25 (4), 435-442, 2009 | 175 | 2009 |
| Intricate interplay between astrocytes and motor neurons in ALS HP Phatnani, P Guarnieri, BA Friedman, MA Carrasco, M Muratet, ... Proceedings of the National Academy of Sciences 110 (8), E756-E765, 2013 | 153 | 2013 |
| Multicluster Pcdh diversity is required for mouse olfactory neural circuit assembly G Mountoufaris, WV Chen, Y Hirabayashi, S O’Keeffe, M Chevee, ... Science 356 (6336), 411-414, 2017 | 147 | 2017 |
| Antisense lncRNA transcription mediates DNA demethylation to drive stochastic protocadherin α promoter choice D Canzio, CL Nwakeze, A Horta, SM Rajkumar, EL Coffey, EE Duffy, ... Cell 177 (3), 639-653. e15, 2019 | 136 | 2019 |
| Pcdhαc2 is required for axonal tiling and assembly of serotonergic circuitries in mice WV Chen, CL Nwakeze, CA Denny, S O’Keeffe, MA Rieger, ... Science 356 (6336), 406-411, 2017 | 136 | 2017 |
| hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function J Ye, N Beetz, S O’Keeffe, JC Tapia, L Macpherson, WV Chen, ... Proceedings of the National Academy of Sciences 112 (23), E3020-E3029, 2015 | 126 | 2015 |
| Common and rare variant associations with clonal haematopoiesis phenotypes MD Kessler, A Damask, S O’Keeffe, N Banerjee, D Li, K Watanabe, ... Nature 612 (7939), 301-309, 2022 | 108 | 2022 |
| Global effects of the CSR-1 RNA interference pathway on the transcriptional landscape G Cecere, S Hoersch, S O'keeffe, R Sachidanandam, A Grishok Nature structural & molecular biology 21 (4), 358-365, 2014 | 101 | 2014 |
| Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals JA Kosmicki, JE Horowitz, N Banerjee, R Lanche, A Marcketta, E Maxwell, ... The American Journal of Human Genetics 108 (7), 1350-1355, 2021 | 86 | 2021 |
| The loss of TBK1 kinase activity in motor neurons or in all cell types differentially impacts ALS disease progression in SOD1 mice V Gerbino, E Kaunga, J Ye, D Canzio, S O’Keeffe, ND Rudnick, ... Neuron 106 (5), 789-805. e5, 2020 | 81 | 2020 |
Tom ManiatisDepartment of Biochemistry and Molecular Biophysics, Columbia University在 columbia.edu 的电子邮件经过验证
