Stochastic protein expression in individual cells at the single molecule level L Cai, N Friedman, XS Xie Nature 440 (7082), 358-362, 2006 | 1412 | 2006 |
Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+ CHL Eng, M Lawson, Q Zhu, R Dries, N Koulena, Y Takei, J Yun, ... Nature 568 (7751), 235-239, 2019 | 1402 | 2019 |
Single-cell phenotyping within transparent intact tissue through whole-body clearing B Yang, JB Treweek, RP Kulkarni, BE Deverman, CK Chen, E Lubeck, ... Cell 158 (4), 945-958, 2014 | 1023 | 2014 |
Single-cell in situ RNA profiling by sequential hybridization E Lubeck, AF Coskun, T Zhiyentayev, M Ahmad, L Cai Nature methods 11 (4), 360-361, 2014 | 885 | 2014 |
Linking Stochastic Dynamics to Population Distribution:<? format?> An Analytical Framework of Gene Expression N Friedman, L Cai, XS Xie Physical review letters 97 (16), 168302, 2006 | 811 | 2006 |
Higher-order inter-chromosomal hubs shape 3D genome organization in the nucleus SA Quinodoz, N Ollikainen, B Tabak, A Palla, JM Schmidt, E Detmar, ... Cell 174 (3), 744-757. e24, 2018 | 773 | 2018 |
In situ transcription profiling of single cells reveals spatial organization of cells in the mouse hippocampus S Shah, E Lubeck, W Zhou, L Cai Neuron 92 (2), 342-357, 2016 | 636 | 2016 |
Frequency-modulated nuclear localization bursts coordinate gene regulation L Cai, CK Dalal, MB Elowitz Nature 455 (7212), 485-490, 2008 | 578 | 2008 |
A stochastic single-molecule event triggers phenotype switching of a bacterial cell PJ Choi, L Cai, K Frieda, XS Xie Science 322 (5900), 442-446, 2008 | 535 | 2008 |
Giotto: a toolbox for integrative analysis and visualization of spatial expression data R Dries, Q Zhu, R Dong, CHL Eng, H Li, K Liu, Y Fu, T Zhao, A Sarkar, ... Genome biology 22, 1-31, 2021 | 522 | 2021 |
Single-cell systems biology by super-resolution imaging and combinatorial labeling E Lubeck, L Cai Nature methods 9 (7), 743-748, 2012 | 520 | 2012 |
The adult human testis transcriptional cell atlas J Guo, EJ Grow, H Mlcochova, GJ Maher, C Lindskog, X Nie, Y Guo, ... Cell research 28 (12), 1141-1157, 2018 | 514 | 2018 |
Synthetic recording and in situ readout of lineage information in single cells KL Frieda, JM Linton, S Hormoz, J Choi, KHK Chow, ZS Singer, ... Nature 541 (7635), 107-111, 2017 | 420 | 2017 |
The human body at cellular resolution: the NIH Human Biomolecular Atlas Program Caltech-UW TMC Cai Long lcai@ caltech. edu 21 b Shendure Jay 9 Trapnell Cole ... Nature 574 (7777), 187-192, 2019 | 400 | 2019 |
Challenges and emerging directions in single-cell analysis GC Yuan, L Cai, M Elowitz, T Enver, G Fan, G Guo, R Irizarry, ... Genome biology 18, 1-8, 2017 | 333 | 2017 |
Dynamic heterogeneity and DNA methylation in embryonic stem cells ZS Singer, J Yong, J Tischler, JA Hackett, A Altinok, MA Surani, L Cai, ... Molecular cell 55 (2), 319-331, 2014 | 302 | 2014 |
Dynamics and spatial genomics of the nascent transcriptome by intron seqFISH S Shah, Y Takei, W Zhou, E Lubeck, J Yun, CHL Eng, N Koulena, ... Cell 174 (2), 363-376. e16, 2018 | 293 | 2018 |
Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping JB Treweek, KY Chan, NC Flytzanis, B Yang, BE Deverman, ... Nature protocols 10 (11), 1860-1896, 2015 | 288 | 2015 |
Integrated spatial genomics reveals global architecture of single nuclei Y Takei, J Yun, S Zheng, N Ollikainen, N Pierson, J White, S Shah, ... Nature 590 (7845), 344-350, 2021 | 277 | 2021 |
Identification of spatially associated subpopulations by combining scRNAseq and sequential fluorescence in situ hybridization data Q Zhu, S Shah, R Dries, L Cai, GC Yuan Nature biotechnology 36 (12), 1183-1190, 2018 | 228 | 2018 |