The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells C Lu, PS Redd, JR Lee, N Savage, K Liu Oncoimmunology 5 (12), e1247135, 2016 | 221 | 2016 |
An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion JD Klement, AV Paschall, PS Redd, ML Ibrahim, C Lu, D Yang, E Celis, ... The Journal of clinical investigation 128 (12), 5549-5560, 2018 | 218 | 2018 |
Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes C Lu, JD Klement, ML Ibrahim, W Xiao, PS Redd, A Nayak-Kapoor, ... Journal for immunotherapy of cancer 7, 1-11, 2019 | 110 | 2019 |
Osteopontin: a key regulator of tumor progression and immunomodulation HR Moorman, D Poschel, JD Klement, C Lu, PS Redd, K Liu Cancers 12 (11), 3379, 2020 | 95 | 2020 |
Myeloid-derived suppressor cells produce IL-10 to elicit DNMT3b-dependent IRF8 silencing to promote colitis-associated colon tumorigenesis ML Ibrahim, JD Klement, C Lu, PS Redd, W Xiao, D Yang, DD Browning, ... Cell reports 25 (11), 3036-3046. e6, 2018 | 84 | 2018 |
The NF-κB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription PS Simon, SK Sharman, C Lu, D Yang, AV Paschall, SS Tulachan, K Liu BMC cancer 15, 1-12, 2015 | 71 | 2015 |
Asah2 represses the p53–Hmox1 axis to protect myeloid-derived suppressor cells from ferroptosis H Zhu, JD Klement, C Lu, PS Redd, D Yang, AD Smith, DB Poschel, J Zou, ... The Journal of Immunology 206 (6), 1395-1404, 2021 | 60 | 2021 |
Autocrine IL6-mediated activation of the STAT3–DNMT axis silences the TNFα–RIP1 necroptosis pathway to sustain survival and accumulation of myeloid-derived suppressor cells AD Smith, C Lu, D Payne, AV Paschall, JD Klement, PS Redd, ML Ibrahim, ... Cancer research 80 (15), 3145-3156, 2020 | 60 | 2020 |
SETD1B activates iNOS expression in myeloid-derived suppressor cells PS Redd, ML Ibrahim, JD Klement, SK Sharman, AV Paschall, D Yang, ... Cancer research 77 (11), 2834-2843, 2017 | 59 | 2017 |
CD133+ CD24lo defines a 5-Fluorouracil-resistant colon cancer stem cell-like phenotype AV Paschall, D Yang, C Lu, PS Redd, JH Choi, CM Heaton, JR Lee, ... Oncotarget 7 (48), 78698, 2016 | 42 | 2016 |
Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment JD Klement, PS Redd, C Lu, AD Merting, DB Poschel, D Yang, ... Cancer Cell 41 (3), 620-636. e9, 2023 | 41 | 2023 |
Loss of Fas expression and function is coupled with colon cancer resistance to immune checkpoint inhibitor immunotherapy W Xiao, ML Ibrahim, PS Redd, JD Klement, C Lu, D Yang, NM Savage, ... Molecular Cancer Research 17 (2), 420-430, 2019 | 40 | 2019 |
Osteopontin blockade immunotherapy increases cytotoxic T lymphocyte lytic activity and suppresses colon tumor progression JD Klement, DB Poschel, C Lu, AD Merting, D Yang, PS Redd, K Liu Cancers 13 (5), 1006, 2021 | 33 | 2021 |
The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis NH Eisa, Y Jilani, K Kainth, P Redd, S Lu, O Bougrine, HA Sater, ... Journal of Biological Chemistry 294 (14), 5246-5260, 2019 | 32 | 2019 |
Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes GL Coe, PS Redd, AV Paschall, C Lu, L Gu, H Cai, T Albers, ... Scientific reports 6 (1), 30816, 2016 | 26 | 2016 |
Expression profiles and function of IL6 in polymorphonuclear myeloid-derived suppressor cells ML Ibrahim, C Lu, JD Klement, PS Redd, D Yang, AD Smith, K Liu Cancer Immunology, Immunotherapy 69, 2233-2245, 2020 | 20 | 2020 |
H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells PS Redd, C Lu, JD Klement, ML Ibrahim, G Zhou, T Kumai, E Celis, K Liu Oncoimmunology 7 (9), e1483302, 2018 | 16 | 2018 |
Lipid Nanoparticle Delivery of Fas Plasmid Restores Fas Expression to Suppress Melanoma Growth In Vivo ZY Al Subeh, DB Poschel, PS Redd, JD Klement, AD Merting, D Yang, ... ACS nano 16 (8), 12695-12710, 2022 | 14 | 2022 |
NF-κB functions as a molecular link between tumor cells and Th1/Tc1 T cells in the tumor microenvironment to exert radiation-mediated tumor suppression PS Simon, K Bardhan, MR Chen, AV Paschall, C Lu, RJ Bollag, FC Kong, ... Oncotarget 7 (17), 23395, 2016 | 14 | 2016 |
Development of mPing‐based activation tags for crop insertional mutagenesis A Johnson, E Mcassey, S Diaz, J Reagin, PS Redd, DR Parrilla, ... Plant direct 5 (1), e00300, 2021 | 10 | 2021 |