Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19 L Gaziano, C Giambartolomei, AC Pereira, A Gaulton, DC Posner, ... Nature medicine 27 (4), 668-676, 2021 | 172 | 2021 |
Systemic lupus erythematosus–a disease with a dysregulated type I interferon system N Hagberg, L Rönnblom Scandinavian journal of immunology 82 (3), 199-207, 2015 | 121 | 2015 |
IFN-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes is promoted by NK cells via MIP-1β and LFA-1 N Hagberg, O Berggren, D Leonard, G Weber, YT Bryceson, GV Alm, ... The Journal of Immunology 186 (9), 5085-5094, 2011 | 113 | 2011 |
The STAT4 SLE risk allele rs7574865 [T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE N Hagberg, M Joelsson, D Leonard, S Reid, ML Eloranta, J Mo, ... Annals of the rheumatic diseases 77 (7), 1070-1077, 2018 | 98 | 2018 |
B lymphocytes enhance interferon‐α production by plasmacytoid dendritic cells O Berggren, N Hagberg, G Weber, GV Alm, L Rönnblom, ML Eloranta Arthritis & Rheumatism 64 (10), 3409-3419, 2012 | 71 | 2012 |
Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes D Leonard, ML Eloranta, N Hagberg, O Berggren, K Tandre, G Alm, ... Annals of the rheumatic diseases 75 (9), 1728-1734, 2016 | 49 | 2016 |
Cytokine production by activated plasmacytoid dendritic cells and natural killer cells is suppressed by an IRAK4 inhibitor K Hjorton, N Hagberg, E Israelsson, L Jinton, O Berggren, JK Sandling, ... Arthritis research & therapy 20, 1-11, 2018 | 48 | 2018 |
Genome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4 C Wang, JK Sandling, N Hagberg, O Berggren, S Sigurdsson, O Karlberg, ... Annals of the rheumatic diseases 72 (1), 96-103, 2013 | 40 | 2013 |
Systemic lupus erythematosus immune complexes increase the expression of SLAM family members CD319 (CRACC) and CD229 (LY-9) on plasmacytoid dendritic cells and CD319 on CD56dim … N Hagberg, J Theorell, H Schlums, ML Eloranta, YT Bryceson, ... The Journal of Immunology 191 (6), 2989-2998, 2013 | 36 | 2013 |
Autoantibodies to killer cell immunoglobulin-like receptors in patients with systemic lupus erythematosus induce natural killer cell hyporesponsiveness F Segerberg, C Lundtoft, S Reid, K Hjorton, D Leonard, G Nordmark, ... Frontiers in immunology 10, 2164, 2019 | 31 | 2019 |
Immunogenetics in systemic lupus erythematosus: transitioning from genetic associations to cellular effects N Hagberg, C Lundtoft, L Rönnblom Scandinavian Journal of Immunology 92 (4), e12894, 2020 | 27 | 2020 |
Functional anti‐CD94/NKG2A and anti‐CD94/NKG2C autoantibodies in patients with systemic lupus erythematosus N Hagberg, J Theorell, K Hjorton, P Spee, ML Eloranta, YT Bryceson, ... Arthritis & Rheumatology 67 (4), 1000-1011, 2015 | 27 | 2015 |
Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases C Lundtoft, P Pucholt, M Martin, M Bianchi, E Lundström, ML Eloranta, ... Arthritis & Rheumatology 74 (8), 1440-1450, 2022 | 24 | 2022 |
Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype O Berggren, N Hagberg, A Alexsson, G Weber, L Rönnblom, ML Eloranta PLoS One 12 (8), e0183946, 2017 | 23 | 2017 |
Interferon-α enhances the IL-12-induced STAT4 activation selectively in carriers of the STAT4 SLE risk allele rs7574865 [T] N Hagberg, L Rönnblom Annals of the Rheumatic Diseases 78 (3), 429-431, 2019 | 20 | 2019 |
Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling C Lundtoft, P Pucholt, J Imgenberg-Kreuz, J Carlsson-Almlöf, ML Eloranta, ... PLoS genetics 16 (10), e1009199, 2020 | 19 | 2020 |
Characterization of selective and potent JAK1 inhibitors intended for the inhaled treatment of asthma M Nilsson, M Rhedin, R Hendrickx, S Berglund, A Piras, P Blomgran, ... Drug design, development and therapy, 2901-2917, 2023 | 18 | 2023 |
Interaction between the STAT4 rs11889341 (T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus S Reid, N Hagberg, JK Sandling, A Alexsson, P Pucholt, C Sjöwall, ... Annals of the rheumatic diseases 80 (9), 1183-1189, 2021 | 17 | 2021 |
VA Million Veteran Program COVID-19 Science Initiative. Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19 L Gaziano, C Giambartolomei, AC Pereira, A Gaulton, DC Posner, ... Nat Med 27 (4), 668-676, 2021 | 16 | 2021 |
The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells K Hjorton, N Hagberg, P Pucholt, ML Eloranta, L Rönnblom Arthritis research & therapy 22, 1-11, 2020 | 16 | 2020 |