On the convergent evolution of animal toxins: conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures M Dauplais, A Lecoq, J Song, J Cotton, N Jamin, B Gilquin, ... Journal of Biological Chemistry 272 (7), 4302-4309, 1997 | 433 | 1997 |
Anti-GQ1b ganglioside antibodies mediate complement-dependent destruction of the motor nerve terminal GM O'Hanlon, JJ Plomp, M Chakrabarti, I Morrison, ER Wagner, ... Brain 124 (5), 893-906, 2001 | 201 | 2001 |
Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice R McGonigal, EG Rowan, KN Greenshields, SK Halstead, PD Humphreys, ... Brain 133 (7), 1944-1960, 2010 | 179 | 2010 |
Anti-ganglioside antibodies can bind peripheral nerve nodes of Ranvier and activate the complement cascade without inducing acute conduction block in vitro K Paparounas, GM O'Hanlon, CP O'Leary, EG Rowan, HJ Willison Brain 122 (5), 807-816, 1999 | 150 | 1999 |
Potassium channel blocking actions of β‐bungarotoxin and related toxins on mouse and frog motor nerve terminals EG Rowan, AL Harvey British journal of pharmacology 94 (3), 839-847, 1988 | 127 | 1988 |
A review of epidemiological, clinical and in vitro physiological studies of envenomation by the scorpion Hemiscorpius lepturus (Hemiscorpiidae) in Iran A Jalali, MH Pipelzadeh, R Sayedian, EG Rowan Toxicon 55 (2-3), 173-179, 2010 | 123 | 2010 |
The ex vivo neurotoxic, myotoxic and cardiotoxic activity of cucurbituril-based macrocyclic drug delivery vehicles R Oun, RS Floriano, L Isaacs, EG Rowan, NJ Wheate Toxicology research 3 (6), 447-455, 2014 | 120 | 2014 |
Characterization of a P2X‐purinoceptor in cultured neurones of the rat dorsal root ganglia SJ Robertson, MG Rae, EG Rowan, C Kennedy British journal of pharmacology 118 (4), 951-956, 1996 | 119 | 1996 |
Crossing the pain barrier: P2 receptors as targets for novel analgesics C Kennedy, TS Assis, AJ Currie, EG Rowan The Journal of physiology 553 (3), 683-694, 2003 | 115 | 2003 |
What can toxins tell us for drug discovery? AL Harvey, KN Bradley, SA Cochran, EG Rowan, JA Pratt, JA Quillfeldt, ... Toxicon 36 (11), 1635-1640, 1998 | 112 | 1998 |
Delineation of the functional site of α-dendrotoxin: The functional topographies of dendrotoxins are different but share a conserved core with those of other Kv1 potassium … S Gasparini, JM Danse, A Lecoq, S Pinkasfeld, S Zinn-Justin, LC Young, ... Journal of Biological Chemistry 273 (39), 25393-25403, 1998 | 109 | 1998 |
Guillain–barre syndrome E Malek, J Salameh Seminars in neurology 39 (05), 589-595, 2019 | 106 | 2019 |
A cysteine-rich motif confers hypoxia sensitivity to mammalian large conductance voltage-and Ca-activated K (BK) channel α-subunits CE McCartney, H McClafferty, JM Huibant, EG Rowan, MJ Shipston, ... Proceedings of the National Academy of Sciences 102 (49), 17870-17876, 2005 | 105 | 2005 |
Pharmacological properties of P2X3‐receptors present in neurones of the rat dorsal root ganglia MG Rae, EG Rowan, C Kennedy British journal of pharmacology 124 (1), 176-180, 1998 | 97 | 1998 |
Mapping the functional anatomy of BgK on Kv1. 1, Kv1. 2, and Kv1. 3: clues to design analogs with enhanced selectivity N Alessandri-Haber, A Lecoq, S Gasparini, G Grangier-Macmath, ... Journal of Biological Chemistry 274 (50), 35653-35661, 1999 | 93 | 1999 |
What does β-bungarotoxin do at the neuromuscular junction? EG Rowan Toxicon 39 (1), 107-118, 2001 | 83 | 2001 |
Effects of charybdotoxin, a blocker of Ca2+ ‐activated K + channels, on motor nerve terminals AJ Anderson, AL Harvey, EG Rowan, PN Strong British journal of pharmacology 95 (4), 1329-1335, 1988 | 82 | 1988 |
Wound healing activity and mechanisms of action of an antibacterial protein from the venom of the eastern diamondback rattlesnake (Crotalus adamanteus) RP Samy, M Kandasamy, P Gopalakrishnakone, BG Stiles, EG Rowan, ... PLoS One 9 (2), e80199, 2014 | 63 | 2014 |
Neuronal expression of GalNAc transferase is sufficient to prevent the age-related neurodegenerative phenotype of complex ganglioside-deficient mice D Yao, R McGonigal, JA Barrie, J Cappell, ME Cunningham, GR Meehan, ... Journal of Neuroscience 34 (3), 880-891, 2014 | 54 | 2014 |
Pharmacological and structural characterization of a novel phospholipase A2 from Micrurus dumerilii carinicauda venom CA Dal Belo, GB Leite, MH Toyama, S Marangoni, AP Corrado, ... Toxicon 46 (7), 736-750, 2005 | 54 | 2005 |