Strategies for stabilization of enzymes in organic solvents V Stepankova, S Bidmanova, T Koudelakova, Z Prokop, R Chaloupkova, ... Acs Catalysis 3 (12), 2823-2836, 2013 | 635 | 2013 |
Machine learning in enzyme engineering S Mazurenko, Z Prokop, J Damborsky ACS Catalysis 10 (2), 1210-1223, 2019 | 340 | 2019 |
Redesigning dehalogenase access tunnels as a strategy for degrading an anthropogenic substrate M Pavlova, M Klvana, Z Prokop, R Chaloupkova, P Banas, M Otyepka, ... Nature chemical biology 5 (10), 727-733, 2009 | 321 | 2009 |
Exacerbation of substrate toxicity by IPTG in Escherichia coli BL21(DE3) carrying a synthetic metabolic pathway P Dvorak, L Chrast, PI Nikel, R Fedr, K Soucek, M Sedlackova, ... Microbial cell factories 14, 1-15, 2015 | 257 | 2015 |
Modification of activity and specificity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26 by engineering of its entrance tunnel R Chaloupková, J Sýkorová, Z Prokop, A Jesenská, M Monincová, ... Journal of Biological Chemistry 278 (52), 52622-52628, 2003 | 197 | 2003 |
Haloalkane dehalogenases: biotechnological applications T Koudelakova, S Bidmanova, P Dvorak, A Pavelka, R Chaloupkova, ... Biotechnology journal 8 (1), 32-45, 2013 | 190 | 2013 |
FireProt: energy-and evolution-based computational design of thermostable multiple-point mutants D Bednar, K Beerens, E Sebestova, J Bendl, S Khare, R Chaloupkova, ... PLoS computational biology 11 (11), e1004556, 2015 | 167 | 2015 |
Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel T Koudelakova, R Chaloupkova, J Brezovsky, Z Prokop, E Sebestova, ... Angewandte Chemie 125 (7), 2013-2017, 2013 | 165 | 2013 |
Engineering enzyme access tunnels P Kokkonen, D Bednar, G Pinto, Z Prokop, J Damborsky Biotechnology advances 37 (6), 107386, 2019 | 164 | 2019 |
FireProt: web server for automated design of thermostable proteins M Musil, J Stourac, J Bendl, J Brezovsky, Z Prokop, J Zendulka, ... Nucleic acids research 45 (W1), W393-W399, 2017 | 159 | 2017 |
Mobility, bioavailability, and toxic effects of cadmium in soil samples Z Prokop, P Cupr, V Zlevorova-Zlamalikova, J Komárek, L Dusek, ... Environmental Research 91 (2), 119-126, 2003 | 143 | 2003 |
Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering Z Prokop, Y Sato, J Brezovsky, T Mozga, R Chaloupkova, T Koudelakova, ... Angewandte Chemie International Edition 49 (35), 6111-6115, 2010 | 135 | 2010 |
Catalytic mechanism of the haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26 Z Prokop, M Monincová, R Chaloupková, M Klvanˇa, Y Nagata, ... Journal of Biological Chemistry 278 (46), 45094-45100, 2003 | 128 | 2003 |
Pathways and mechanisms for product release in the engineered haloalkane dehalogenases explored using classical and random acceleration molecular dynamics simulations M Klvana, M Pavlova, T Koudelakova, R Chaloupkova, P Dvorak, ... Journal of molecular biology 392 (5), 1339-1356, 2009 | 124 | 2009 |
Enzymes fight chemical weapons Z Prokop, F Opluštil, J DeFrank, J Damborský Biotechnology Journal: Healthcare Nutrition Technology 1 (12), 1370-1380, 2006 | 113 | 2006 |
Two Rhizobial Strains, Mesorhizobium loti MAFF303099 and Bradyrhizobium japonicum USDA110, Encode Haloalkane Dehalogenases with Novel Structures … Y Sato, M Monincová, R Chaloupková, Z Prokop, Y Ohtsubo, ... Applied and environmental microbiology 71 (8), 4372-4379, 2005 | 113 | 2005 |
Halide-stabilizing residues of haloalkane dehalogenases studied by quantum mechanic calculations and site-directed mutagenesis M Bohác, Y Nagata, Z Prokop, M Prokop, M Monincová, M Tsuda, J Koca, ... Biochemistry 41 (48), 14272-14280, 2002 | 110 | 2002 |
Engineering a de novo transport tunnel J Brezovsky, P Babkova, O Degtjarik, A Fortova, A Gora, I Iermak, ... ACS Catalysis 6 (11), 7597-7610, 2016 | 105 | 2016 |
Degradation of β-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26 Y Nagata, Z Prokop, Y Sato, P Jerabek, A Kumar, Y Ohtsubo, M Tsuda, ... Applied and environmental microbiology 71 (4), 2183-2185, 2005 | 94 | 2005 |
A single mutation in a tunnel to the active site changes the mechanism and kinetics of product release in haloalkane dehalogenase LinB L Biedermannová, Z Prokop, A Gora, E Chovancová, M Kovács, ... Journal of Biological Chemistry 287 (34), 29062-29074, 2012 | 93 | 2012 |