Design, synthesis and in vitro antimicrobial evaluation of novel Imidazo [1, 2-a] pyridine and imidazo [2, 1-b][1, 3] benzothiazole motifs TH Al-Tel, RA Al-Qawasmeh, R Zaarour European journal of medicinal chemistry 46 (5), 1874-1881, 2011 | 272 | 2011 |
Synthesis and antimicrobial activity of cholic acid hydrazone analogues AJM Rasras, TH Al-Tel, AF Al-Aboudi, RA Al-Qawasmeh European journal of medicinal chemistry 45 (6), 2307-2313, 2010 | 121 | 2010 |
Triaryl methane derivatives as antiproliferative agents RA Al-Qawasmeh, Y Lee, MY Cao, X Gu, A Vassilakos, JA Wright, ... Bioorganic & medicinal chemistry letters 14 (2), 347-350, 2004 | 105 | 2004 |
Post Groebke–Blackburn multicomponent protocol: synthesis of new polyfunctional imidazo [1, 2-a] pyridine and imidazo [1, 2-a] pyrimidine derivatives as potential antimicrobial … TH Al-Tel, RA Al-Qawasmeh European journal of medicinal chemistry 45 (12), 5848-5855, 2010 | 102 | 2010 |
Design, synthesis, and qualitative structure–activity evaluations of novel β-Secretase inhibitors as potential Alzheimer’s drug leads TH Al-Tel, MH Semreen, RA Al-Qawasmeh, MF Schmidt, R El-Awadi, ... Journal of medicinal chemistry 54 (24), 8373-8385, 2011 | 59 | 2011 |
The synthesis and conformation of 2′-and 3′-hypermodified tricyclic nucleosides and their use in the synthesis of novel 2′-or 3′-isomeric 4 (7)-substituted isoxazolidine … J Rong, P Roselt, J Plavec, J Chattopadhyaya Tetrahedron 50 (16), 4921-4936, 1994 | 52* | 1994 |
Rapid Assembly of Polyfunctional Structures Using a One‐Pot Five‐and Six‐Component Sequential Groebke–Blackburn/Ugi/Passerini Process TH Al‐Tel, RA Al‐Qawasmeh, W Voelter European Journal of Organic Chemistry 2010 (29), 5586-5593, 2010 | 51 | 2010 |
Rational design and synthesis of potent dibenzazepine motifs as β-secretase inhibitors TH Al-Tel, RA Al-Qawasmeh, MF Schmidt, A Al-Aboudi, SN Rao, SS Sabri, ... Journal of medicinal chemistry 52 (20), 6484-6488, 2009 | 46 | 2009 |
Potent antimicrobial activity of 3-(4, 5-diaryl-1H-imidazol-2-yl)-1H-indole derivatives against methicillin-resistant Staphylococcus aureus RA Al-Qawasmeh, M Huesca, V Nedunuri, R Peralta, J Wright, Y Lee, ... Bioorganic & medicinal chemistry letters 20 (12), 3518-3520, 2010 | 41 | 2010 |
11-Phenyl-[b, e]-dibenzazepine compounds: novel antitumor agents RA Al-Qawasmeh, Y Lee, MY Cao, X Gu, S Viau, J Lightfoot, JA Wright, ... Bioorganic & Medicinal Chemistry Letters 19 (1), 104-107, 2009 | 36 | 2009 |
Design, synthesis and SAR analysis of potent BACE1 inhibitors: Possible lead drug candidates for Alzheimer's disease H Tarazi, RA Odeh, R Al-Qawasmeh, IA Yousef, W Voelter, TH Al-Tel European Journal of Medicinal Chemistry 125, 1213-1224, 2017 | 32 | 2017 |
A novel small molecule with potent anticancer activity inhibits cell growth by modulating intracellular labile zinc homeostasis M Huesca, LS Lock, AA Khine, S Viau, R Peralta, IH Cukier, H Jin, ... Molecular cancer therapeutics 8 (9), 2586-2596, 2009 | 32 | 2009 |
NC381, a novel anticancer agent, arrests the cell cycle in G0-G1 and inhibits lung tumor cell growth in vitro and in vivo MY Cao, Y Lee, NP Feng, RA Al-Qawasmeh, S Viau, XP Gu, L Lau, H Jin, ... Journal of Pharmacology and Experimental Therapeutics 308 (2), 538-546, 2004 | 26 | 2004 |
Base-Mediated 1, 6-Aza-Michael Addition of Heterocyclic Amines and Amides to para-Quinone Methides Leading to Meclizine-, Hydroxyzine-and Cetirizine-like Architectures D Roy, G Panda Synthesis 51 (23), 4434-4442, 2019 | 23 | 2019 |
Tandem multicomponent reactions toward the design and synthesis of novel antibacterial and cytotoxic motifs M H Semreen, R El-Awady, R Abu-Odeh, M Saber-Ayad, ... Current medicinal chemistry 20 (11), 1445-1459, 2013 | 23 | 2013 |
Synthesis and antibacterial activity of 9-cyclopropyl-4-fluoro-6-oxo-6, 9-dihydro-[1, 2, 5] thiadiazolo [3, 4-h] quinoline-7-carboxylic acid and its ethyl ester. RA Al-Qawasmeh, JA Zahra, F Zani, P Vicini, R Boese, MM El-Abadelah Arkivoc: Online Journal of Organic Chemistry, 2009 | 19 | 2009 |
Design and synthesis of new energy restriction mimetic agents: potent anti-tumor activities of hybrid motifs of aminothiazoles and coumarins F Hersi, HA Omar, RA Al-Qawasmeh, Z Ahmad, AM Jaber, DM Zaher, ... Scientific Reports 10 (1), 2893, 2020 | 18 | 2020 |
In-silico identification of the binding mode of synthesized adamantyl derivatives inside cholinesterase enzymes A Al-Aboudi, RA Al-Qawasmeh, A Shahwan, U Mahmood, A Khalid, ... Acta Pharmacologica Sinica 36 (7), 879-886, 2015 | 17 | 2015 |
Monitoring of liquid‐phase peptide synthesis on soluble polymer supports via matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry R Thürmer, M Meisenbach, H Echner, A Weiler, RA Al‐Qawasmeh, ... Rapid communications in mass spectrometry 12 (7), 398-402, 1998 | 17 | 1998 |
Magnetic silica surface functionalized palladium catalyst: a modular approach for CC cross-coupling reactions in water K Hasan, IA Shehadi, KA Bagudu, NOM Elmabrouk, A Elgamouz, ... Applied Surface Science 571, 151369, 2022 | 15 | 2022 |