High-grade serous ovarian cancer arises from fallopian tube in a mouse model J Kim, DM Coffey, CJ Creighton, Z Yu, SM Hawkins, MM Matzuk Proceedings of the National Academy of Sciences 109 (10), 3921-3926, 2012 | 489 | 2012 |
Molecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancers CJ Creighton, MD Fountain, Z Yu, AK Nagaraja, H Zhu, M Khan, E Olokpa, ... Cancer research 70 (5), 1906-1915, 2010 | 314 | 2010 |
A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer AK Nagaraja, CJ Creighton, Z Yu, H Zhu, PH Gunaratne, JG Reid, ... Molecular Endocrinology 24 (2), 447-463, 2010 | 294 | 2010 |
The dual actions of morin (3, 5, 7, 2′, 4′-pentahydroxyflavone) as a hypouricemic agent: uricosuric effect and xanthine oxidase inhibitory activity Z Yu, WP Fong, CHK Cheng Journal of Pharmacology and Experimental Therapeutics 316 (1), 169-175, 2006 | 167 | 2006 |
Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice H Miyata, JM Castaneda, Y Fujihara, Z Yu, DR Archambeault, A Isotani, ... Proceedings of the National Academy of Sciences 113 (28), 7704-7710, 2016 | 153 | 2016 |
Spermatozoa lacking Fertilization Influencing Membrane Protein (FIMP) fail to fuse with oocytes in mice Y Fujihara, Y Lu, T Noda, A Oji, T Larasati, K Kojima-Kita, Z Yu, ... Proceedings of the National Academy of Sciences 117 (17), 9393-9400, 2020 | 83 | 2020 |
TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa JM Castaneda, R Hua, H Miyata, A Oji, Y Guo, Y Cheng, T Zhou, X Guo, ... Proceedings of the National Academy of Sciences 114 (27), E5370-E5378, 2017 | 78 | 2017 |
NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility D Kiyozumi, T Noda, R Yamaguchi, T Tobita, T Matsumura, K Shimada, ... Science 368 (6495), 1132-1135, 2020 | 75 | 2020 |
A Mild, DNA-Compatible Nitro Reduction Using B2(OH)4 HC Du, N Simmons, JC Faver, Z Yu, M Palaniappan, K Riehle, ... Organic Letters 21 (7), 2194-2199, 2019 | 63 | 2019 |
Morin (3, 5, 7, 2′, 4′-pentahydroxyflavone) exhibits potent inhibitory actions on urate transport by the human urate anion transporter (hURAT1) expressed in human embryonic … Z Yu, WP Fong, CHK Cheng Drug metabolism and disposition 35 (6), 981-986, 2007 | 63 | 2007 |
Quantitative comparison of enrichment from DNA-encoded chemical library selections JC Faver, K Riehle, DR Lancia Jr, JBJ Milbank, CS Kollmann, N Simmons, ... ACS combinatorial science 21 (2), 75-82, 2019 | 60 | 2019 |
Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice Y Fujihara, T Noda, K Kobayashi, A Oji, S Kobayashi, T Matsumura, ... Proceedings of the National Academy of Sciences 116 (37), 18498-18506, 2019 | 58 | 2019 |
Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets MJ Robertson, K Kent, N Tharp, K Nozawa, L Dean, M Mathew, SL Grimm, ... BMC biology 18, 1-28, 2020 | 57 | 2020 |
DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors S Chamakuri, S Lu, MN Ucisik, KM Bohren, YC Chen, HC Du, JC Faver, ... Proceedings of the National Academy of Sciences 118 (36), e2111172118, 2021 | 49 | 2021 |
Discovery and characterization of bromodomain 2–specific inhibitors of BRDT Z Yu, AF Ku, JL Anglin, R Sharma, MN Ucisik, JC Faver, F Li, ... Proceedings of the National Academy of Sciences 118 (9), e2021102118, 2021 | 49 | 2021 |
Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library S Dawadi, N Simmons, G Miklossy, KM Bohren, JC Faver, MN Ucisik, ... Proceedings of the National Academy of Sciences 117 (29), 16782-16789, 2020 | 49 | 2020 |
C–N coupling of DNA-conjugated (hetero) aryl bromides and chlorides for DNA-encoded chemical library synthesis YC Chen, JC Faver, AF Ku, G Miklossy, K Riehle, KM Bohren, MN Ucisik, ... Bioconjugate Chemistry 31 (3), 770-780, 2020 | 45 | 2020 |
ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility K Shimada, S Park, H Miyata, Z Yu, A Morohoshi, S Oura, MM Matzuk, ... Proceedings of the National Academy of Sciences 118 (6), e2018355118, 2021 | 43 | 2021 |
The testis-specific serine proteases PRSS44, PRSS46, and PRSS54 are dispensable for male mouse fertility RJ Holcomb, S Oura, K Nozawa, K Kent, Z Yu, MJ Robertson, C Coarfa, ... Biology of Reproduction 102 (1), 84-91, 2020 | 39 | 2020 |
Facile, Efficient, and Enantiospecific Syntheses of 1,1‘-N-Linked Pseudodisaccharides as a New Class of Glycosidase Inhibitors TKM Shing, CSK Kwong, AWC Cheung, SHL Kok, Z Yu, J Li, CHK Cheng Journal of the American Chemical Society 126 (49), 15990-15992, 2004 | 36 | 2004 |