| Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition H Ding, Z Chen, K Wu, SM Huang, WL Wu, SE LeBoeuf, RG Pillai, ... Science Advances 7 (47), eabk1023, 2021 | 54 | 2021 |
| A novel recurrent CHEK2 Y390C mutation identified in high-risk Chinese breast cancer patients impairs its activity and is associated with increased breast cancer risk N Wang, H Ding, C Liu, X Li, L Wei, J Yu, M Liu, M Ying, W Gao, H Jiang, ... Oncogene 34 (40), 5198-5205, 2015 | 30 | 2015 |
| Systematic analysis of drug vulnerabilities conferred by tumor suppressor loss H Ding, J Zhao, Y Zhang, J Yu, M Liu, X Li, L Xu, M Lin, C Liu, Z He, ... Cell Reports 27 (11), 3331-3344. e6, 2019 | 28 | 2019 |
| A DNA/HDAC dual‐targeting drug CY 190602 with significantly enhanced anticancer potency C Liu, H Ding, X Li, CP Pallasch, L Hong, D Guo, Y Chen, D Wang, ... EMBO Molecular Medicine 7 (4), 438-449, 2015 | 28 | 2015 |
| SHANK2 is a frequently amplified oncogene with evolutionarily conserved roles in regulating Hippo signaling L Xu, P Li, X Hao, Y Lu, M Liu, W Song, L Shan, J Yu, H Ding, S Chen, ... Protein & Cell 12 (3), 174-193, 2021 | 15 | 2021 |
| Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer R Pillai, SE LeBoeuf, Y Hao, C New, JLE Blum, A Rashidfarrokhi, ... Science Advances 10 (13), eadm9859, 2024 | 10 | 2024 |
| UBQLN4 is an ATM substrate that stabilizes the anti‐apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma F Liu, RS Pan, HY Ding, LL Gu, Y Yang, CY Li, YJ Xu, R Hu, H Chen, ... Molecular Oncology 15 (12), 3738-3752, 2021 | 9 | 2021 |
| BAP1 regulates AMPK-mTOR signalling pathway through deubiquitinating and stabilizing tumour-suppressor LKB1 C Yang, H Ding, Y Yang, L Yang, Y Yang, M Fang, J Ren, R Hu, C Wang, ... Biochemical and Biophysical Research Communications 529 (4), 1025-1032, 2020 | 9 | 2020 |
| Defining relative mutational difficulty to understand cancer formation L Shan, J Yu, Z He, S Chen, M Liu, H Ding, L Xu, J Zhao, A Yang, H Jiang Cell discovery 6 (1), 48, 2020 | 5 | 2020 |
| Screening for bacterial enzymes synthesizing GPR119 agonist in cAMP-responsive cells J Jia, Y Chen, L Xu, Y Yang, X Xu, H Ding, C Jia, H Gao, P Guo, R Hu Acta Biochimica et Biophysica Sinica 53 (1), 121-123, 2021 | 2 | 2021 |
