Direct regulation of BK channels by phosphatidylinositol 4, 5-bisphosphate as a novel signaling pathway T Vaithianathan, A Bukiya, J Liu, P Liu, M Asuncion-Chin, Z Fan, A Dopico The Journal of general physiology 132 (1), 13-28, 2008 | 110 | 2008 |
Multiple cholesterol recognition/interaction amino acid consensus (CRAC) motifs in cytosolic C tail of Slo1 subunit determine cholesterol sensitivity of Ca2+-and voltage-gated … AK Singh, J McMillan, AN Bukiya, B Burton, AL Parrill, AM Dopico Journal of Biological Chemistry 287 (24), 20509-20521, 2012 | 108 | 2012 |
β1 (KCNMB1) subunits mediate lithocholate activation of large-conductance Ca2+-activated K+ channels and dilation in small, resistance-size arteries AN Bukiya, J Liu, L Toro, AM Dopico Molecular pharmacology 72 (2), 359-369, 2007 | 99 | 2007 |
Specificity of cholesterol and analogs to modulate BK channels points to direct sterol–channel protein interactions AN Bukiya, JD Belani, S Rychnovsky, AM Dopico The Journal of general physiology 137 (1), 93-110, 2011 | 94 | 2011 |
Large conductance, calcium-and voltage-gated potassium (BK) channels: regulation by cholesterol AM Dopico, AN Bukiya, AK Singh Pharmacology & therapeutics 135 (2), 133-150, 2012 | 86 | 2012 |
An alcohol-sensing site in the calcium-and voltage-gated, large conductance potassium (BK) channel AN Bukiya, G Kuntamallappanavar, J Edwards, AK Singh, B Shivakumar, ... Proceedings of the National Academy of Sciences 111 (25), 9313-9318, 2014 | 77 | 2014 |
The BK channel accessory β 1 subunit determines alcohol-induced cerebrovascular constriction AN Bukiya, J Liu, AM Dopico FEBS letters 583 (17), 2779-2784, 2009 | 67 | 2009 |
Sizing up Ethanol‐Induced Plasticity: The Role of Small and Large Conductance Calcium‐Activated Potassium Channels PJ Mulholland, FW Hopf, AN Bukiya, GE Martin, J Liu, AM Dopico, A Bonci, ... Alcoholism: Clinical and Experimental Research 33 (7), 1125-1135, 2009 | 64 | 2009 |
Smooth muscle cholesterol enables BK β1 subunit-mediated channel inhibition and subsequent vasoconstriction evoked by alcohol AN Bukiya, T Vaithianathan, G Kuntamallappanavar, M Asuncion-Chin, ... Arteriosclerosis, thrombosis, and vascular biology 31 (11), 2410-2423, 2011 | 57 | 2011 |
Ethanol modulation of mammalian BK channels in excitable tissues: molecular targets and their possible contribution to alcohol-induced altered behavior AM Dopico, AN Bukiya, GE Martin Frontiers in physiology 5, 2014 | 56 | 2014 |
The steroid interaction site in transmembrane domain 2 of the large conductance, voltage-and calcium-gated potassium (BK) channel accessory β1 subunit AN Bukiya, AK Singh, AL Parrill, AM Dopico Proceedings of the National Academy of Sciences 108 (50), 20207-20212, 2011 | 51 | 2011 |
Channel β2–4 subunits fail to substitute for β1 in sensitizing BK channels to lithocholate AN Bukiya, T Vaithianathan, L Toro, AM Dopico Biochemical and biophysical research communications 390 (3), 995-1000, 2009 | 48 | 2009 |
The second transmembrane domain of the large conductance, voltage-and calcium-gated potassium channel β 1 subunit is a lithocholate sensor AN Bukiya, T Vaithianathan, L Toro, AM Dopico FEBS letters 582 (5), 673-678, 2008 | 48 | 2008 |
Cerebrovascular dilation via selective targeting of the cholane steroid-recognition site in the BK channel β1-subunit by a novel nonsteroidal agent AN Bukiya, JE McMillan, AL Fedinec, SA Patil, DD Miller, CW Leffler, ... Molecular pharmacology 83 (5), 1030-1044, 2013 | 47 | 2013 |
Lipid regulation of BK channel function AM Dopico, AN Bukiya Frontiers in physiology 5, 2014 | 45 | 2014 |
Hypercholesterolemia induces up-regulation of KACh cardiac currents via a mechanism independent of phosphatidylinositol 4, 5-bisphosphate and Gβγ W Deng, AN Bukiya, AA Rodríguez-Menchaca, Z Zhang, CM Baumgarten, ... Journal of Biological Chemistry 287 (7), 4925-4935, 2012 | 41 | 2012 |
Structural determinants of monohydroxylated bile acids to activate β1 subunit-containing BK channels AN Bukiya, J McMillan, AL Parrill, AM Dopico Journal of lipid research 49 (11), 2441-2451, 2008 | 36 | 2008 |
Dietary Cholesterol Protects Against Alcohol‐Induced Cerebral Artery Constriction A Bukiya, AM Dopico, CW Leffler, A Fedinec Alcoholism: Clinical and Experimental Research 38 (5), 1216-1226, 2014 | 28 | 2014 |
Activation of Calcium-and Voltage-gated Potassium Channels of Large Conductance by Leukotriene B4 AN Bukiya, J McMillan, J Liu, B Shivakumar, AL Parrill, AM Dopico Journal of Biological Chemistry 289 (51), 35314-35325, 2014 | 21 | 2014 |
Type 2 ryanodine receptors are highly sensitive to alcohol Y Ye, K Jian, JH Jaggar, AN Bukiya, AM Dopico FEBS letters 588 (9), 1659-1665, 2014 | 20 | 2014 |