Improvements to healthspan through environmental enrichment and lifestyle interventions: where are we now? NJ Queen, QN Hassan, L Cao Frontiers in Neuroscience 14, 605, 2020 | 51 | 2020 |
Targeting visceral fat by intraperitoneal delivery of novel AAV serotype vector restricting off-target transduction in liver W Huang, X Liu, NJ Queen, L Cao Molecular therapy Methods & clinical development 6, 68-78, 2017 | 50 | 2017 |
Long-term environmental enrichment affects microglial morphology in middle age mice S Ali, X Liu, NJ Queen, RS Patel, RK Wilkins, X Mo, L Cao Aging (Albany NY) 11 (8), 2388, 2019 | 48 | 2019 |
Hypothalamic gene transfer of BDNF promotes healthy aging in mice T McMurphy, W Huang, X Liu, JJ Siu, NJ Queen, R Xiao, L Cao Aging Cell 18 (2), e12846, 2019 | 42 | 2019 |
Implementation of environmental enrichment after middle age promotes healthy aging T McMurphy, W Huang, NJ Queen, S Ali, KJ Widstrom, X Liu, R Xiao, ... Aging (Albany NY) 10 (7), 1698, 2018 | 42 | 2018 |
Environmental enrichment improves metabolic and behavioral health in the BTBR mouse model of autism NJ Queen, AA Boardman, RS Patel, JJ Siu, X Mo, L Cao Psychoneuroendocrinology 111, 104476, 2020 | 41 | 2020 |
CSF1R inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice S Ali, AG Mansour, W Huang, NJ Queen, X Mo, JM Anderson, ... Aging (Albany NY) 12 (3), 2101, 2020 | 40 | 2020 |
Improved gene delivery to adult mouse spinal cord through the use of engineered hybrid adeno-associated viral serotypes JJ Siu, NJ Queen, W Huang, FQ Yin, X Liu, C Wang, DM McTigue, L Cao Gene therapy 24 (6), 361-369, 2017 | 40 | 2017 |
Enriched environment regulates thymocyte development and alleviates experimental autoimmune encephalomyelitis in mice R Xiao, SM Bergin, W Huang, AG Mansour, X Liu, RT Judd, KJ Widstrom, ... Brain, behavior, and immunity 75, 137-148, 2019 | 39 | 2019 |
Adipose PTEN regulates adult adipose tissue homeostasis and redistribution via a PTEN-leptin-sympathetic loop W Huang, NJ Queen, TB McMurphy, S Ali, L Cao Molecular metabolism 30, 48-60, 2019 | 35 | 2019 |
Adipocytes: a novel target for IL-15/IL-15Rα cancer gene therapy R Xiao, AG Mansour, W Huang, LA Chrislip, RK Wilkins, NJ Queen, ... Molecular Therapy 27 (5), 922-932, 2019 | 31 | 2019 |
Visceral adipose tissue-directed FGF21 gene therapy improves metabolic and immune health in BTBR mice NJ Queen, R Bates, W Huang, R Xiao, B Appana, L Cao Molecular Therapy-Methods & Clinical Development 20, 409-422, 2021 | 22 | 2021 |
Enriched environment inhibits breast cancer progression in obese models with intact leptin signaling GD Foglesong, NJ Queen, W Huang, KJ Widstrom, L Cao Endocrine-related cancer 26 (5), 483-495, 2019 | 20 | 2019 |
Molecular therapy of melanocortin-4-receptor obesity by an autoregulatory BDNF vector JJ Siu, NJ Queen, X Liu, W Huang, T McMurphy, L Cao Molecular Therapy Methods & Clinical Development 7, 83-95, 2017 | 18 | 2017 |
rAAV-mediated gene delivery to adipose tissue W Huang, NJ Queen, L Cao Adeno-Associated Virus Vectors: Design and Delivery, 389-405, 2019 | 14 | 2019 |
Hypothalamic AAV-BDNF gene therapy improves metabolic function and behavior in the Magel2-null mouse model of Prader-Willi syndrome NJ Queen, X Zou, JM Anderson, W Huang, B Appana, S Komatineni, ... Molecular Therapy-Methods & Clinical Development 27, 131-148, 2022 | 10 | 2022 |
Environmental activation of a hypothalamic BDNF-adipocyte IL-15 axis regulates adipose-natural killer cells SM Bergin, R Xiao, W Huang, CRT Judd, X Liu, AG Mansour, N Queen, ... Brain, behavior, and immunity 95, 477-488, 2021 | 10 | 2021 |
Enriched environment enhances NK cell maturation through hypothalamic BDNF in male mice AG Mansour, R Xiao, SM Bergin, W Huang, LA Chrislip, J Zhang, S Ali, ... European journal of immunology 51 (3), 557-566, 2021 | 9 | 2021 |
Adipose PTEN acts as a downstream mediator of a brain-fat axis in environmental enrichment W Huang, NJ Queen, TB McMurphy, S Ali, RK Wilkins, B Appana, L Cao Comprehensive psychoneuroendocrinology 4, 100013, 2020 | 8 | 2020 |
Social isolation exacerbates diet-induced obesity and peripheral inflammation in young male mice under thermoneutrality NJ Queen, W Huang, S Komatineni, AG Mansour, R Xiao, LA Chrislip, ... Iscience 26 (3), 2023 | 7 | 2023 |