Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function V Kain, KA Ingle, RA Colas, J Dalli, SD Prabhu, CN Serhan, M Joshi, ... Journal of molecular and cellular cardiology 84, 24-35, 2015 | 252 | 2015 |
Inflammation revisited: inflammation versus resolution of inflammation following myocardial infarction V Kain, SD Prabhu, GV Halade Basic research in cardiology 109, 1-17, 2014 | 222 | 2014 |
High glucose-induced Ca2+ overload and oxidative stress contribute to apoptosis of cardiac cells through mitochondrial dependent and independent pathways S Kumar, V Kain, SL Sitasawad Biochimica et Biophysica Acta (BBA)-General Subjects 1820 (7), 907-920, 2012 | 120 | 2012 |
Splenic leukocytes define the resolution of inflammation in heart failure GV Halade, PC Norris, V Kain, CN Serhan, KA Ingle Science signaling 11 (520), eaao1818, 2018 | 109 | 2018 |
Cardiomyocyte-specific Bmal1 deletion in mice triggers diastolic dysfunction, extracellular matrix response, and impaired resolution of inflammation KA Ingle, V Kain, M Goel, SD Prabhu, ME Young, GV Halade American Journal of Physiology-Heart and Circulatory Physiology 309 (11 …, 2015 | 93 | 2015 |
Obesity superimposed on aging magnifies inflammation and delays the resolving response after myocardial infarction EF Lopez, JH Kabarowski, KA Ingle, V Kain, S Barnes, DK Crossman, ... American Journal of Physiology-Heart and Circulatory Physiology 308 (4 …, 2015 | 85 | 2015 |
Aging dysregulates D-and E-series resolvins to modulate cardiosplenic and cardiorenal network following myocardial infarction GV Halade, V Kain, LM Black, SD Prabhu, KA Ingle Aging (Albany NY) 8 (11), 2611, 2016 | 83 | 2016 |
Simvastatin may induce insulin resistance through a novel fatty acid mediated cholesterol independent mechanism V Kain, B Kapadia, P Misra, U Saxena Scientific reports 5 (1), 13823, 2015 | 74 | 2015 |
Doxorubicin triggers splenic contraction and irreversible dysregulation of COX and LOX that alters the inflammation-resolution program in the myocardium JK Jadapalli, GW Wright, V Kain, MA Sherwani, R Sonkar, N Yusuf, ... American Journal of Physiology-Heart and Circulatory Physiology 315 (5 …, 2018 | 66 | 2018 |
Immune responsive resolvin D1 programs myocardial infarction–induced cardiorenal syndrome in heart failure GV Halade, V Kain, CN Serhan The FASEB Journal 32 (7), 3717, 2018 | 65 | 2018 |
Resolution Agonist 15-epi-Lipoxin A4 Programs Early Activation of Resolving Phase in Post-Myocardial Infarction Healing V Kain, F Liu, V Kozlovskaya, KA Ingle, S Bolisetty, A Agarwal, S Khedkar, ... Scientific reports 7 (1), 9999, 2017 | 62 | 2017 |
Molecular and cellular differences in cardiac repair of male and female mice AB Pullen, V Kain, CN Serhan, GV Halade Journal of the American Heart Association 9 (8), e015672, 2020 | 60 | 2020 |
Excess ω-6 fatty acids influx in aging drives metabolic dysregulation, electrocardiographic alterations, and low-grade chronic inflammation V Kain, KA Ingle, M Kachman, H Baum, G Shanmugam, NS Rajasekaran, ... American Journal of Physiology-Heart and Circulatory Physiology 314 (2 …, 2018 | 57 | 2018 |
Obesogenic diet in aging mice disrupts gut microbe composition and alters neutrophil: lymphocyte ratio, leading to inflamed milieu in acute heart failure V Kain, W Van Der Pol, N Mariappan, A Ahmad, P Eipers, DL Gibson, ... The FASEB Journal 33 (5), 6456, 2019 | 54 | 2019 |
Obesity and cardiometabolic defects in heart failure pathology GV Halade, V Kain Comprehensive Physiology 7 (4), 1463, 2017 | 54 | 2017 |
Heart functional and structural compendium of cardiosplenic and cardiorenal networks in acute and chronic heart failure pathology GV Halade, V Kain, KA Ingle American Journal of Physiology-Heart and Circulatory Physiology 314 (2 …, 2018 | 52 | 2018 |
Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis V Kain, S Kumar, SL Sitasawad Cardiovascular Diabetology 10, 1-12, 2011 | 52 | 2011 |
Genetic deletion of 12/15 lipoxygenase promotes effective resolution of inflammation following myocardial infarction V Kain, KA Ingle, J Kabarowski, S Barnes, NA Limdi, SD Prabhu, ... Journal of molecular and cellular cardiology 118, 70-80, 2018 | 49 | 2018 |
Lack of resolution sensor drives age-related cardiometabolic and cardiorenal defects and impedes inflammation-resolution in heart failure B Tourki, V Kain, AB Pullen, PC Norris, N Patel, P Arora, X Leroy, ... Molecular metabolism 31, 138-149, 2020 | 48 | 2020 |
Role of neutrophils in ischemic heart failure V Kain, GV Halade Pharmacology & therapeutics 205, 107424, 2020 | 46 | 2020 |