Activation of an IL6 inflammatory loop mediates trastuzumab resistance in HER2+ breast cancer by expanding the cancer stem cell population H Korkaya, G Kim, A Davis, F Malik, NL Henry, S Ithimakin, AA Quraishi, ... Molecular cell 47 (4), 570-584, 2012 | 584 | 2012 |
Overexpression of cyclin B1 in early-stage non-small cell lung cancer and its clinical implication JC Soria, SJ Jang, FR Khuri, K Hassan, D Liu, WK Hong, L Mao Cancer research 60 (15), 4000-4004, 2000 | 410 | 2000 |
Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade M Ouzounova, E Lee, R Piranlioglu, A El Andaloussi, R Kolhe, ... Nature communications 8 (1), 14979, 2017 | 353 | 2017 |
Activation of melanoma antigen tumor antigens occurs early in lung carcinogenesis SJ Jang, JC Soria, L Wang, KA Hassan, RC Morice, GL Walsh, WK Hong, ... Cancer research 61 (21), 7959-7963, 2001 | 226 | 2001 |
Notch pathway activity identifies cells with cancer stem cell–like properties and correlates with worse survival in lung adenocarcinoma KA Hassan, L Wang, H Korkaya, G Chen, I Maillard, DG Beer, ... Clinical cancer research 19 (8), 1972-1980, 2013 | 225 | 2013 |
Effect of midtreatment PET/CT-adapted radiation therapy with concurrent chemotherapy in patients with locally advanced non–small-cell lung cancer: a phase 2 clinical trial FM Kong, RK Ten Haken, M Schipper, KA Frey, J Hayman, M Gross, ... JAMA oncology 3 (10), 1358-1365, 2017 | 218 | 2017 |
Loss of PTEN expression as a prognostic marker for tongue cancer JI Lee, JC Soria, KA Hassan, AK El-Naggar, X Tang, DD Liu, WK Hong, ... Archives of Otolaryngology–Head & Neck Surgery 127 (12), 1441-1445, 2001 | 186 | 2001 |
Hypermethylation of the Retinoic Acid Receptor-β2 Gene in Head and Neck Carcinogenesis EM Youssef, D Lotan, JP Issa, K Wakasa, YH Fan, L Mao, K Hassan, ... Clinical Cancer Research 10 (5), 1733-1742, 2004 | 165 | 2004 |
Notch reporter activity in breast cancer cell lines identifies a subset of cells with stem cell activity RC D'Angelo, M Ouzounova, A Davis, D Choi, SM Tchuenkam, G Kim, ... Molecular cancer therapeutics 14 (3), 779-787, 2015 | 146 | 2015 |
Cyclin B1 overexpression and resistance to radiotherapy in head and neck squamous cell carcinoma KA Hassan, KK Ang, AK El-Naggar, MD Story, JI Lee, D Liu, WK Hong, ... Cancer research 62 (22), 6414-6417, 2002 | 136 | 2002 |
Loss of Fhit expression is a predictor of poor outcome in tongue cancer JI Lee, JC Soria, K Hassan, D Liu, X Tang, A El-Naggar, WK Hong, L Mao Cancer research 61 (3), 837-841, 2001 | 107 | 2001 |
Clinical significance of cyclin B1 protein expression in squamous cell carcinoma of the tongue KA Hassan, AK El-Naggar, JC Soria, D Liu, WK Hong, L Mao Clinical Cancer Research 7 (8), 2458-2462, 2001 | 101 | 2001 |
Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model R Piranlioglu, EM Lee, M Ouzounova, RJ Bollag, AH Vinyard, AS Arbab, ... Nature communications 10 (1), 1430, 2019 | 95 | 2019 |
Effects of insulin-like growth factor binding protein-3 and farnesyltransferase inhibitor SCH66336 on Akt expression and apoptosis in non–small-cell lung cancer cells HY Lee, H Moon, KH Chun, YS Chang, K Hassan, L Ji, R Lotan, FR Khuri, ... Journal of the National Cancer Institute 96 (20), 1536-1548, 2004 | 82 | 2004 |
High-throughput label-free isolation of heterogeneous circulating tumor cells and CTC clusters from non-small-cell lung cancer patients M Zeinali, M Lee, A Nadhan, A Mathur, C Hedman, E Lin, R Harouaka, ... Cancers 12 (1), 127, 2020 | 81 | 2020 |
An embryonic stem cell–like signature identifies poorly differentiated lung adenocarcinoma but not squamous cell carcinoma KA Hassan, G Chen, GP Kalemkerian, MS Wicha, DG Beer Clinical cancer research 15 (20), 6386-6390, 2009 | 67 | 2009 |
Changes in global function and regional ventilation and perfusion on SPECT during the course of radiotherapy in patients with non-small-cell lung cancer KA Frey, MD Gross, JA Hayman, D Arenberg, XW Cai, N Ramnath, ... International Journal of Radiation Oncology* Biology* Physics 82 (4), e631-e638, 2012 | 62 | 2012 |
Implication of protein kinase B/Akt and Bcl-2/Bcl-XL suppression by the farnesyl transferase inhibitor SCH66336 in apoptosis induction in squamous carcinoma cells KH Chun, HY Lee, K Hassan, F Khuri, WK Hong, R Lotan Cancer research 63 (16), 4796-4800, 2003 | 61 | 2003 |
Loss of Fhit expression in head and neck squamous cell carcinoma and its potential clinical implication SK Tai, JI Lee, KK Ang, AK El-Naggar, KA Hassan, D Liu, JJ Lee, H Ren, ... Clinical cancer research 10 (16), 5554-5557, 2004 | 51 | 2004 |
Lung cancer stem cell: fancy conceptual model of tumor biology or cornerstone of a forthcoming therapeutic breakthrough? T Sourisseau, KA Hassan, I Wistuba, F Penault-Llorca, J Adam, E Deutsch, ... Journal of Thoracic Oncology 9 (1), 7-17, 2014 | 38 | 2014 |