An electrophilic warhead library for mapping the reactivity and accessibility of tractable cysteines in protein kinases L Petri, A Egyed, D Bajusz, T Imre, A Hetényi, T Martinek, ... European Journal of Medicinal Chemistry 207, 112836, 2020 | 34 | 2020 |
PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells S Prokop, P Ábrányi-Balogh, B Barti, M Vámosi, M Zöldi, L Barna, ... Nature Communications 12 (1), 6505, 2021 | 30 | 2021 |
The impact of the secondary binding pocket on the pharmacology of class A GPCRs A Egyed, DJ Kiss, GM Keserű Frontiers in pharmacology 13, 847788, 2022 | 12 | 2022 |
Discovery of a novel kinase hinge binder fragment by dynamic undocking M Rachman, D Bajusz, A Hetényi, A Scarpino, B Merő, A Egyed, L Buday, ... RSC Medicinal Chemistry 11 (5), 552-558, 2020 | 12 | 2020 |
Controlling receptor function from the extracellular vestibule of G-protein coupled receptors A Egyed, K Domány-Kovács, B Koványi, F Horti, D Kurkó, DJ Kiss, ... Chemical Communications 56 (91), 14167-14170, 2020 | 12 | 2020 |
Controlling the selectivity of aminergic GPCR ligands from the extracellular vestibule A Egyed, ÁA Kelemen, M Vass, A Visegrády, SA Thee, Z Wang, ... Bioorganic Chemistry 111, 104832, 2021 | 10 | 2021 |
The impact of binding site waters on the activity/selectivity trade-off of Janus kinase 2 (JAK2) inhibitors A Egyed, D Bajusz, GM Keserű Bioorganic & Medicinal Chemistry 27 (8), 1497-1508, 2019 | 5 | 2019 |
Safe and Efficient Continuous-Flow Synthesis and Batchwise Hydrolysis of Ethyl 5-Acetyl-1H-pyrazole-3-carboxylate: A Key Synthon of Darolutamide B Szilágyi, A Egyed, I Mándity, T Nagy, K Kátai-Fadgyas, B Volk, ... Synthesis 55 (06), 959-966, 2023 | 2 | 2023 |
Development of a silicone-based polymer matrix as a suitable Transdermal Therapeutic System for diallyl disulfide S László, Z Hajna, A Egyed, E Pintér, Ö Wagner Pharmaceuticals 15 (10), 1182, 2022 | 1 | 2022 |