Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity FA Ran, PD Hsu, CY Lin, JS Gootenberg, S Konermann, AE Trevino, ... Cell 154 (6), 1380-1389, 2013 | 4227 | 2013 |
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex S Konermann, MD Brigham, AE Trevino, J Joung, OO Abudayyeh, ... Nature 517 (7536), 583-588, 2015 | 2950 | 2015 |
An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues MR Corces, AE Trevino, EG Hamilton, PG Greenside, ... Nature methods 14 (10), 959-962, 2017 | 1876 | 2017 |
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells X Wu, DA Scott, AJ Kriz, AC Chiu, PD Hsu, DB Dadon, AW Cheng, ... Nature biotechnology 32 (7), 670-676, 2014 | 1162 | 2014 |
Optical control of mammalian endogenous transcription and epigenetic states S Konermann, MD Brigham, AE Trevino, PD Hsu, M Heidenreich, L Cong, ... Nature 500 (7463), 472-476, 2013 | 1065 | 2013 |
Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution AE Trevino, F Müller, J Andersen, L Sundaram, A Kathiria, A Shcherbina, ... Cell 184 (19), 5053-5069. e23, 2021 | 256 | 2021 |
Chromatin accessibility dynamics in a model of human forebrain development AE Trevino, N Sinnott-Armstrong, J Andersen, SJ Yoon, N Huber, ... Science 367 (6476), eaay1645, 2020 | 201 | 2020 |
Genome editing using Cas9 nickases AE Trevino, F Zhang Methods in enzymology 546, 161-174, 2014 | 154 | 2014 |
Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements J Tycko, M Wainberg, GK Marinov, O Ursu, GT Hess, BK Ego, Aradhana, ... Nature communications 10 (1), 4063, 2019 | 112 | 2019 |
Nociceptor neurons affect cancer immunosurveillance M Balood, M Ahmadi, T Eichwald, A Ahmadi, A Majdoubi, K Roversi, ... Nature 611 (7935), 405-412, 2022 | 86 | 2022 |
Graph deep learning for the characterization of tumour microenvironments from spatial protein profiles in tissue specimens Z Wu, AE Trevino, E Wu, K Swanson, HJ Kim, HB D’Angio, R Preska, ... Nature Biomedical Engineering 6 (12), 1435-1448, 2022 | 57 | 2022 |
Diverse lncRNA mechanisms in brain development and disease CE Ang, AE Trevino, HY Chang Current opinion in genetics & development 65, 42-46, 2020 | 51 | 2020 |
Transcription-dependent domain-scale three-dimensional genome organization in the dinoflagellate Breviolum minutum GK Marinov, AE Trevino, T Xiang, A Kundaje, AR Grossman, ... Nature Genetics 53 (5), 613-617, 2021 | 46 | 2021 |
Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems S Konermann, A Trevino, M Brigham, RAN Fei, P Hsu, C Lin, O Nureki, ... US Patent 10,550,372, 2020 | 36 | 2020 |
Functional screening with optimized functional CRISPR-Cas systems F Zhang, S Konermann, MD Brigham, A Trevino US Patent 11,001,829, 2021 | 28 | 2021 |
Omni-ATAC-seq: improved ATAC-seq protocol MR Corces, SW Cho, HY Chang, WJ Greenleaf, TJ Montine, PA Khavari, ... | 16 | 2017 |
7-UP: Generating in silico CODEX from a small set of immunofluorescence markers E Wu, AE Trevino, Z Wu, K Swanson, HJ Kim, HB D’Angio, R Preska, ... PNAS nexus 2 (6), pgad171, 2023 | 13 | 2023 |
Single‐Cell Transcriptomic Census of Endothelial Changes Induced by Matrix Stiffness and the Association with Atherosclerosis M Zamani, YH Cheng, F Charbonier, VK Gupta, AT Mayer, AE Trevino, ... Advanced functional materials 32 (47), 2203069, 2022 | 12 | 2022 |
SPACE-GM: geometric deep learning of disease-associated microenvironments from multiplex spatial protein profiles Z Wu, AE Trevino, E Wu, K Swanson, HJ Kim, HB D’Angio, R Preska, ... bioRxiv, 2022.05. 12.491707, 2022 | 7 | 2022 |
emObject: domain specific data abstraction for spatial omics EAG Baker, MY Huang, A Lam, MK Rahim, MF Bieniosek, B Wang, ... bioRxiv, 2023.06. 07.543950, 2023 | 5 | 2023 |