Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism WF Bosron, TK Li Hepatology 6 (3), 502-510, 1986 | 722 | 1986 |
Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2 (2) allele is dominant. DW Crabb, HJ Edenberg, WF Bosron, TK Li The Journal of clinical investigation 83 (1), 314-316, 1989 | 702 | 1989 |
Characterization of CPT-11 hydrolysis by human liver carboxylesterase isoforms hCE-1 and hCE-2 R Humerickhouse, K Lohrbach, L Li, WF Bosron, ME Dolan Cancer research 60 (5), 1189-1192, 2000 | 446 | 2000 |
Current progress on esterases: from molecular structure to function T Satoh, P Taylor, WF Bosron, SP Sanghani, M Hosokawa, BN La Du Drug Metabolism and Disposition 30 (5), 488-493, 2002 | 352 | 2002 |
Research advances in ethanol metabolism VA Ramchandani, WF Bosron, TK Li Pathologie Biologie 49 (9), 676-682, 2001 | 337 | 2001 |
Human liver cocaine esterases: ethanol‐mediated formation of ethylcocaine RA Dean, CD Christian, RHB Sample, WF Bosron The FASEB journal 5 (12), 2735-2739, 1991 | 313 | 1991 |
Genetic factors in alcohol metabolism and alcoholism WF Bosron, T Ehrig, TK Li Seminars in liver disease 13 (02), 126-135, 1993 | 267 | 1993 |
Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1 Z Sun, DJ Murry, SP Sanghani, WI Davis, NY Kedishvili, Q Zou, TD Hurley, ... Journal of Pharmacology and Experimental Therapeutics 310 (2), 469-476, 2004 | 253 | 2004 |
Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin EV Pindel, NY Kedishvili, TL Abraham, MR Brzezinski, J Zhang, RA Dean, ... Journal of Biological Chemistry 272 (23), 14769-14775, 1997 | 253 | 1997 |
Genotyping of human alcohol dehydrogenases at the ADH2 and ADH3 loci following DNA sequence amplification Y Xu, LG Carr, WF Bosron, TK Li, HJ Edenberg Genomics 2 (3), 209-214, 1988 | 241 | 1988 |
Metabolism of cocaine and heroin is catalyzed by the same human liver carboxylesterases. LM Kamendulis, MR Brzezinski, EV Pindel, WF Bosron, RA Dean Journal of pharmacology and experimental therapeutics 279 (2), 713-717, 1996 | 237 | 1996 |
Purification and characterization of a human liver cocaine carboxylesterase that catalyzes the production of benzoylecgonine and the formation of cocaethylene from alcohol and … MR Brzezinski, TL Abraham, CL Stone, RA Dean, WF Bosron Biochemical pharmacology 48 (9), 1747-1755, 1994 | 214 | 1994 |
Hydrolysis of capecitabine to 5′-deoxy-5-fluorocytidine by human carboxylesterases and inhibition by loperamide SK Quinney, SP Sanghani, WI Davis, TD Hurley, Z Sun, DJ Murry, ... Journal of Pharmacology and Experimental Therapeutics 313 (3), 1011-1016, 2005 | 202 | 2005 |
Isolation of II-alcohol dehydrogenase of human liver: Is it a determinant of alcoholism? TK Li, WF Bosron, WP Dafeldecker, LG Lange Proceedings of the National Academy of Sciences 74 (10), 4378-4381, 1977 | 200 | 1977 |
Catalytic efficiency of human alcohol dehydrogenases for retinol oxidation and retinal reduction ZN Yang, GJ Davis, TD Hurley, CL Stone, TK Li, WF Bosron Alcoholism: Clinical and Experimental Research 18 (3), 587-591, 1994 | 196 | 1994 |
Alcohol dehydrogenases HJ Edenberg, WF Bosron Comprehensive toxicology, 111-130, 2010 | 193 | 2010 |
Ethanol metabolism DW Crabb, WF Bosron, TK Li Pharmacology & therapeutics 34 (1), 59-73, 1987 | 185 | 1987 |
Kinetic and electrophoretic properties of native and recombined isoenzymes of human liver alcohol dehydrogenase WF Bosron, LJ Magnes, TK Li Biochemistry 22 (8), 1852-1857, 1983 | 176 | 1983 |
Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis SP Sanghani, SK Quinney, TB Fredenburg, Z Sun, WI Davis, DJ Murry, ... Clinical cancer research 9 (13), 4983-4991, 2003 | 175 | 2003 |
Alcohol and aldehyde dehydrogenase T EHRIG, WF BOSRON, TKAI LI Alcohol and alcoholism 25 (2-3), 105-116, 1990 | 172 | 1990 |