Colorectal cancer chemoprevention by trans-resveratrol ME Juan, I Alfaras, JM Planas Pharmacological Research 65 (6), 584-591, 2012 | 145 | 2012 |
The bioavailability and distribution of trans-resveratrol are constrained by ABC transporters JM Planas, I Alfaras, H Colom, ME Juan Archives of Biochemistry and Biophysics 527 (2), 67-73, 2012 | 137 | 2012 |
Pharmacological strategies to retard cardiovascular aging I Alfaras, C Di Germanio, M Bernier, A Csiszar, Z Ungvari, EG Lakatta, ... Circulation research 118 (10), 1626-1642, 2016 | 77 | 2016 |
Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet M Bernier, D Wahl, A Ali, J Allard, S Faulkner, A Wnorowski, M Sanghvi, ... Aging (Albany NY) 8 (5), 899, 2016 | 74 | 2016 |
GH receptor deficiency in Ecuadorian adults is associated with obesity and enhanced insulin sensitivity J Guevara-Aguirre, AL Rosenbloom, P Balasubramanian, E Teran, ... The Journal of Clinical Endocrinology & Metabolism 100 (7), 2589-2596, 2015 | 72 | 2015 |
A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice MA Petr, I Alfaras, M Krawcyzk, WN Bair, SJ Mitchell, CH Morrell, ... Elife 10, e62952, 2021 | 64 | 2021 |
Involvement of Breast Cancer Resistance Protein (BCRP1/ABCG2) in the Bioavailability and Tissue Distribution of trans-Resveratrol in Knockout Mice I Alfaras, M Perez, ME Juan, G Merino, JG Prieto, JM Planas, AI Álvarez Journal of agricultural and food chemistry 58 (7), 4523-4528, 2010 | 62 | 2010 |
A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entry Y Chen, TB Lear, JW Evankovich, MB Larsen, B Lin, I Alfaras, ... Nature communications 12 (1), 3907, 2021 | 57 | 2021 |
Health benefits of late-onset metformin treatment every other week in mice I Alfaras, SJ Mitchell, H Mora, DR Lugo, A Warren, I Navas-Enamorado, ... NPJ aging and mechanisms of disease 3 (1), 16, 2017 | 56 | 2017 |
trans-Resveratrol Reduces Precancerous Colonic Lesions in Dimethylhydrazine-Treated Rats I Alfaras, ME Juan, JM Planas Journal of agricultural and food chemistry 58 (13), 8104-8110, 2010 | 52 | 2010 |
Population Pharmacokinetic Modeling of trans-Resveratrol and Its Glucuronide and Sulfate Conjugates After Oral and Intravenous Administration in Rats H Colom, I Alfaras, M Maijó, ME Juan, JM Planas Pharmaceutical research 28, 1606-1621, 2011 | 48 | 2011 |
Determination of dihydroresveratrol in rat plasma by HPLC ME Juan, I Alfaras, JM Planas Journal of agricultural and food chemistry 58 (12), 7472-7475, 2010 | 42 | 2010 |
Study of longitudinal aging in mice: presentation of experimental techniques DL Palliyaguru, C Vieira Ligo Teixeira, E Duregon, C di Germanio, ... The Journals of Gerontology: Series A 76 (4), 552-560, 2021 | 39 | 2021 |
Of aging mice and men: gait speed decline is a translatable trait, with species-specific underlying properties WN Bair, M Petr, I Alfaras, SJ Mitchell, M Bernier, L Ferrucci, SA Studenski, ... The Journals of Gerontology: Series A 74 (9), 1413-1416, 2019 | 32 | 2019 |
Muscle cannabinoid 1 receptor regulates Il-6 and myostatin expression, governing physical performance and whole-body metabolism I González-Mariscal, RA Montoro, JF O’Connell, Y Kim, ... The FASEB Journal 33 (5), 5850, 2019 | 32 | 2019 |
Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan MA Aon, S Cortassa, M Juhaszova, JA González-Reyes, M Calvo-Rubio, ... npj Aging and Mechanisms of Disease 7 (1), 1, 2021 | 18 | 2021 |
Modulation of lysosomal function as a therapeutic approach for coronaviral infections Y Liu, T Lear, M Larsen, B Lin, Q Cao, I Alfaras, J Kennerdell, L Salminen, ... Research Square, 2021 | 11 | 2021 |
A high throughput screen for TMPRSS2 expression identifies FDA-approved and clinically advanced compounds that can limit SARS-CoV-2 entry Y Chen, TB Lear, JW Evankovich, MB Larsen, B Lin, I Alfaras, ... Research Square, 2020 | 10 | 2020 |
Empirical versus theoretical power and type I error (false-positive) rates estimated from real murine aging research data I Alfaras, K Ejima, CVL Teixeira, C Di Germanio, SJ Mitchell, S Hamilton, ... Cell reports 36 (7), 2021 | 6 | 2021 |
Sex differences in response to metformin in a longitudinal study in mice CVL Teixeira, I Alfaras, S Camadola, N Price, M Bernier, R de Cabo Innovation in Aging 4 (Supplement_1), 518-518, 2020 | 2 | 2020 |