The angiosuppressive effects of 20 (R)-ginsenoside Rg3 PYK Yue, DYL Wong, PK Wu, PY Leung, NK Mak, HW Yeung, L Liu, Z Cai, ... Biochemical pharmacology 72 (4), 437-445, 2006 | 278 | 2006 |
MEK1/2 inhibitors: molecular activity and resistance mechanisms PK Wu, JI Park Seminars in oncology 42 (6), 849-862, 2015 | 137 | 2015 |
Raf/MEK/ERK can regulate cellular levels of LC3B and SQSTM1/p62 at expression levels JH Kim, SK Hong, PK Wu, AL Richards, WT Jackson, JI Park Experimental cell research 327 (2), 340-352, 2014 | 123 | 2014 |
A mortalin/HSPA9-mediated switch in tumor-suppressive signaling of Raf/MEK/extracellular signal-regulated kinase PK Wu, SK Hong, S Veeranki, M Karkhanis, D Starenki, JA Plaza, JI Park Molecular and Cellular Biology, 2013 | 79 | 2013 |
Growth inhibitory signaling of the Raf/MEK/ERK pathway PK Wu, A Becker, JI Park International journal of molecular sciences 21 (15), 5436, 2020 | 71 | 2020 |
Oleanolic acid isolated from Oldenlandia diffusa exhibits a unique growth inhibitory effect against ras-transformed fibroblasts PK Wu, WCS Tai, ZT Liang, ZZ Zhao, WLW Hsiao Life sciences 85 (3-4), 113-121, 2009 | 38 | 2009 |
Mortalin (HSPA9) facilitates BRAF-mutant tumor cell survival by suppressing ANT3-mediated mitochondrial membrane permeability PK Wu, SK Hong, W Chen, AE Becker, RL Gundry, CW Lin, H Shao, ... Science signaling 13 (622), eaay1478, 2020 | 34 | 2020 |
Mortalin/HSPA9 targeting selectively induces KRAS tumor cell death by perturbing mitochondrial membrane permeability PK Wu, SK Hong, D Starenki, K Oshima, H Shao, JE Gestwicki, S Tsai, ... Oncogene 39 (21), 4257-4270, 2020 | 33 | 2020 |
Chemical and DNA authentication of taste variants of Gynostemma pentaphyllum herbal tea PK Wu, WCS Tai, RCY Choi, KWK Tsim, H Zhou, X Liu, ZH Jiang, ... Food chemistry 128 (1), 70-80, 2011 | 32 | 2011 |
ERK1/2 can feedback-regulate cellular MEK1/2 levels SK Hong, PK Wu, M Karkhanis, JI Park Cellular signalling 27 (10), 1939-1948, 2015 | 29 | 2015 |
A cellular threshold for active ERK1/2 levels determines Raf/MEK/ERK-mediated growth arrest versus death responses SK Hong, PK Wu, JI Park Cellular signalling 42, 11-20, 2018 | 27 | 2018 |
Suppression of B-RafV600E melanoma cell survival by targeting mitochondria using triphenyl-phosphonium-conjugated nitroxide or ubiquinone SK Hong, D Starenki, PK Wu, JI Park Cancer biology & therapy 18 (2), 106-114, 2017 | 27 | 2017 |
Involvement of protein kinase C and E2F-5 in euxanthone-induced neurite differentiation of neuroblastoma WY Ha, PK Wu, TW Kok, KW Leung, NK Mak, PYK Yue, SM Ngai, SN Tsai, ... The International Journal of Biochemistry & Cell Biology 38 (8), 1393-1401, 2006 | 27 | 2006 |
Steady-state levels of phosphorylated mitogen-activated protein kinase kinase 1/2 determined by mortalin/HSPA9 and protein phosphatase 1 alpha in KRAS and BRAF tumor cells PK Wu, SK Hong, JI Park Molecular and Cellular Biology, 2017 | 26 | 2017 |
Active ERK 2 is sufficient to mediate growth arrest and differentiation signaling PK Wu, SK Hong, SH Yoon, JI Park The FEBS journal 282 (6), 1017-1030, 2015 | 26 | 2015 |
Vandetanib and cabozantinib potentiate mitochondria-targeted agents to suppress medullary thyroid carcinoma cells D Starenki, SK Hong, PK Wu, JI Park Cancer biology & therapy 18 (7), 473-483, 2017 | 20 | 2017 |
Mortalin depletion induces MEK/ERK-dependent and ANT/CypD-mediated death in vemurafenib-resistant B-RafV600E melanoma cells PK Wu, SK Hong, JI Park Cancer letters 502, 25-33, 2021 | 19 | 2021 |
Medical College of Wisconsin PK Wu United States, 0 | 19 | |
The Predicted Proteomic Network Associated with the Antiarthritic Action of Qingfu Guanjieshu in Collagen‐II‐Induced Arthritis in Rats TY Wang, H Zhou, YF Wong, PK Wu, WLW Hsiao, ELH Leung, L Liu Evidence‐Based Complementary and Alternative Medicine 2013 (1), 582493, 2013 | 9 | 2013 |
Anticancer activities and the drug targets of botanical saponins from a medicinal herb, Gynostemma pentaphyllum WLW Hsiao, WCS Tai, Z Mo, PK Wu Journal of Acupuncture and Tuina Science 6 (5), 271-272, 2008 | 7 | 2008 |