| A novel mammalian flavin-dependent histone demethylase A Karytinos, F Forneris, A Profumo, G Ciossani, E Battaglioli, C Binda, ... Journal of Biological Chemistry 284 (26), 17775-17782, 2009 | 359 | 2009 |
| Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2 C Binda, S Valente, M Romanenghi, S Pilotto, R Cirilli, A Karytinos, ... Journal of the American Chemical Society 132 (19), 6827-6833, 2010 | 350 | 2010 |
| Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities D Rotili, S Tomassi, M Conte, R Benedetti, M Tortorici, G Ciossani, ... Journal of medicinal chemistry 57 (1), 42-55, 2014 | 135 | 2014 |
| Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase M Tortorici, MT Borrello, M Tardugno, LR Chiarelli, S Pilotto, G Ciossani, ... ACS chemical biology 8 (8), 1677-1682, 2013 | 83 | 2013 |
| Differential properties of transcriptional complexes formed by the CoREST family ÁP Barrios, AV Gómez, JE Sáez, G Ciossani, E Toffolo, E Battaglioli, ... Molecular and cellular biology, 2014 | 81 | 2014 |
| Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and … L Sartori, C Mercurio, F Amigoni, A Cappa, G Faga, R Fattori, E Legnaghi, ... Journal of Medicinal Chemistry 60 (5), 1673-1692, 2017 | 80 | 2017 |
| Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and … P Vianello, L Sartori, F Amigoni, A Cappa, G Faga, R Fattori, E Legnaghi, ... Journal of Medicinal Chemistry 60 (5), 1693-1715, 2017 | 75 | 2017 |
| Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features V Speranzini, D Rotili, G Ciossani, S Pilotto, B Marrocco, M Forgione, ... Science advances 2 (9), e1601017, 2016 | 69 | 2016 |
| Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A P Vianello, OA Botrugno, A Cappa, G Ciossani, P Dessanti, A Mai, ... European journal of medicinal chemistry 86, 352-363, 2014 | 69 | 2014 |
| The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases G Ciossani, K Overlack, A Petrovic, C Koerner, S Wohlgemuth, S Maffini, ... Journal of Biological Chemistry 293 (26), 10084-10101, 2018 | 64 | 2018 |
| Cyclin B1 scaffolds MAD 1 at the kinetochore corona to activate the mitotic checkpoint LA Allan, M Camacho Reis, G Ciossani, PJ Huis in ‘t Veld, S Wohlgemuth, ... The EMBO journal 39 (12), e103180, 2020 | 49 | 2020 |
| Electroporated recombinant proteins as tools for in vivo functional complementation, imaging and chemical biology A Alex, V Piano, S Polley, M Stuiver, S Voss, G Ciossani, K Overlack, ... Elife 8, e48287, 2019 | 42 | 2019 |
| Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blasts S Valente, V Rodriguez, C Mercurio, P Vianello, B Saponara, R Cirilli, ... European journal of medicinal chemistry 94, 163-174, 2015 | 39 | 2015 |
| Expanding the druggable space of the LSD1/CoREST epigenetic target: new potential binding regions for drug-like molecules, peptides, protein partners, and chromatin JC Robertson, NC Hurley, M Tortorici, G Ciossani, MT Borrello, ... PLoS computational biology 9 (7), e1003158, 2013 | 39 | 2013 |
| A tail-based mechanism drives nucleosome demethylation by the LSD2/NPAC multimeric complex C Marabelli, B Marrocco, S Pilotto, S Chittori, S Picaud, S Marchese, ... Cell Reports 27 (2), 387-399. e7, 2019 | 32 | 2019 |
| Pyrrole-and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells V Rodriguez, S Valente, S Rovida, D Rotili, G Stazi, A Lucidi, G Ciossani, ... MedChemComm 6 (4), 665-670, 2015 | 31 | 2015 |
| Structure of the RZZ complex and molecular basis of Spindly‐driven corona assembly at human kinetochores T Raisch, G Ciossani, E d’Amico, V Cmentowski, S Carmignani, S Maffini, ... The EMBO journal 41 (9), e110411, 2022 | 25 | 2022 |
| Huis In’t Veld PJ, Wohlgemuth S, Kops GJ, Musacchio A, Saurin AT (2020) Cyclin B1 scaffolds MAD1 at the kinetochore corona to activate the mitotic checkpoint LA Allan, M Camacho Reis, G Ciossani EMBO J 39 (12), e103180, 0 | 24 | |
| Huis In’t Veld PJ, Koerner C, Wohlgemuth S, Maffini S, Musacchio A (2018) The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB … G Ciossani, K Overlack, A Petrovic J Biol Chem 293, 10084-10101, 0 | 24 | |
| Pure diastereomers of a tranylcypromine-based LSD1 inhibitor: enzyme selectivity and in-cell studies S Valente, V Rodriguez, C Mercurio, P Vianello, B Saponara, R Cirilli, ... ACS Medicinal Chemistry Letters 6 (2), 173-177, 2015 | 23 | 2015 |
