Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning CM Sellgren, J Gracias, B Watmuff, JD Biag, JM Thanos, PB Whittredge, ... Nature neuroscience 22 (3), 374-385, 2019 | 636 | 2019 |
CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors A Sugathan, M Biagioli, C Golzio, S Erdin, I Blumenthal, P Manavalan, ... Proceedings of the National Academy of Sciences 111 (42), E4468-E4477, 2014 | 343 | 2014 |
Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome SD Sheridan, KM Theriault, SA Reis, F Zhou, JM Madison, L Daheron, ... PloS one 6 (10), e26203, 2011 | 339 | 2011 |
MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling N Mellios, DA Feldman, SD Sheridan, JPK Ip, S Kwok, SK Amoah, ... Molecular psychiatry 23 (4), 1051-1065, 2018 | 236 | 2018 |
Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities JM Madison, F Zhou, A Nigam, A Hussain, DD Barker, R Nehme, ... Molecular psychiatry 20 (6), 703-717, 2015 | 188 | 2015 |
Molecular signatures of human induced pluripotent stem cells highlight sex differences and cancer genes MC Anguera, R Sadreyev, Z Zhang, A Szanto, B Payer, SD Sheridan, ... Cell stem cell 11 (1), 75-90, 2012 | 173 | 2012 |
Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder S Bavamian, N Mellios, J Lalonde, DM Fass, J Wang, SD Sheridan, ... Molecular psychiatry 20 (5), 573-584, 2015 | 167 | 2015 |
Patient-specific models of microglia-mediated engulfment of synapses and neural progenitors CM Sellgren, SD Sheridan, J Gracias, D Xuan, T Fu, RH Perlis Molecular psychiatry 22 (2), 170-177, 2017 | 156 | 2017 |
Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway X Lojewski, JF Staropoli, S Biswas-Legrand, AM Simas, L Haliw, MK Selig, ... Human molecular genetics 23 (8), 2005-2022, 2014 | 145 | 2014 |
Inhibition of p25/Cdk5 attenuates tauopathy in mouse and iPSC models of frontotemporal dementia J Seo, O Kritskiy, LA Watson, SJ Barker, D Dey, WK Raja, YT Lin, T Ko, ... Journal of Neuroscience 37 (41), 9917-9924, 2017 | 143 | 2017 |
Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis BTD Tobe, AM Crain, AM Winquist, B Calabrese, H Makihara, W Zhao, ... Proceedings of the National Academy of Sciences 114 (22), E4462-E4471, 2017 | 137 | 2017 |
Activation of gene expression by a novel DNA structural transmission mechanism that requires supercoiling-induced DNA duplex destabilization in an upstream activating sequence SD Sheridan, CJ Benham, GW Hatfield Journal of Biological Chemistry 273 (33), 21298-21308, 1998 | 135 | 1998 |
Analysis of embryoid bodies derived from human induced pluripotent stem cells as a means to assess pluripotency SD Sheridan, V Surampudi, RR Rao Stem cells international 2012 (1), 738910, 2012 | 105 | 2012 |
Cis-acting regulation of brain-specific ANK3 gene expression by a genetic variant associated with bipolar disorder EH Rueckert, D Barker, D Ruderfer, SE Bergen, C O'Dushlaine, CJ Luce, ... Molecular psychiatry 18 (8), 922-929, 2013 | 90 | 2013 |
A high-throughput screen for Wnt/β-catenin signaling pathway modulators in human iPSC-derived neural progenitors WN Zhao, C Cheng, KM Theriault, SD Sheridan, LH Tsai, SJ Haggarty Journal of biomolecular screening 17 (9), 1252-1263, 2012 | 85 | 2012 |
Contribution of network connectivity in determining the relationship between gene expression and metabolite concentration changes A Zelezniak, S Sheridan, KR Patil PLoS computational biology 10 (4), e1003572, 2014 | 81 | 2014 |
β2-Adrenergic receptor agonist ameliorates phenotypes and corrects microRNA-mediated IGF1 deficits in a mouse model of Rett syndrome N Mellios, J Woodson, RI Garcia, B Crawford, J Sharma, SD Sheridan, ... Proceedings of the National Academy of Sciences 111 (27), 9947-9952, 2014 | 80 | 2014 |
Stem cell differentiation S Sheridan US Patent App. 10/156,602, 2003 | 73 | 2003 |
Pendant drop control in a multiwell plate K DeSilets, M Emerick, C Scott, S Sheridan US Patent App. 11/062,113, 2005 | 61 | 2005 |
Exosomal secretion of a psychosis-altered miRNA that regulates glutamate receptor expression is affected by antipsychotics SK Amoah, BA Rodriguez, CN Logothetis, P Chander, CM Sellgren, ... Neuropsychopharmacology 45 (4), 656-665, 2020 | 58 | 2020 |