Impact of cavitation, high shear stress and air/liquid interfaces on protein aggregation M Duerkop, E Berger, A Dürauer, A Jungbauer Biotechnology journal 13 (7), 1800062, 2018 | 105 | 2018 |
Hybrid modeling and intensified DoE: an approach to accelerate upstream process characterization B Bayer, G Striedner, M Duerkop Biotechnology journal 15 (9), 2000121, 2020 | 45 | 2020 |
A comprehensive antigen production and characterisation study for easy-to-implement, specific and quantitative SARS-CoV-2 serotests M Klausberger, M Duerkop, H Haslacher, G Wozniak-Knopp, ... EBioMedicine 67, 2021 | 43 | 2021 |
Influence of cavitation and high shear stress on HSA aggregation behavior M Duerkop, E Berger, A Dürauer, A Jungbauer Engineering in life sciences 18 (3), 169-178, 2018 | 42 | 2018 |
Hybrid modeling of cross-flow filtration: Predicting the flux evolution and duration of ultrafiltration processes M Krippl, A Dürauer, M Duerkop Separation and Purification Technology 248, 117064, 2020 | 39 | 2020 |
Comparison of modeling methods for DoE‐based holistic upstream process characterization B Bayer, M von Stosch, G Striedner, M Duerkop Biotechnology Journal 15 (5), 1900551, 2020 | 39 | 2020 |
Digital twin application for model-based doe to rapidly identify ideal process conditions for space-time yield optimization B Bayer, R Dalmau Diaz, M Melcher, G Striedner, M Duerkop Processes 9 (7), 1109, 2021 | 35 | 2021 |
The shortcomings of accurate rate estimations in cultivation processes and a solution for precise and robust process modeling B Bayer, B Sissolak, M Duerkop, M Von Stosch, G Striedner Bioprocess and biosystems engineering 43, 169-178, 2020 | 25 | 2020 |
Hybrid modeling reduces experimental effort to predict performance of serial and parallel single-pass tangential flow filtration M Krippl, T Kargl, M Duerkop, A Dürauer Separation and Purification Technology 276, 119277, 2021 | 22 | 2021 |
Model transferability and reduced experimental burden in cell culture process development facilitated by hybrid modeling and intensified design of experiments B Bayer, M Duerkop, G Striedner, B Sissolak Frontiers in Bioengineering and Biotechnology 9, 740215, 2021 | 21 | 2021 |
Soft sensor based on 2D‐fluorescence and process data enabling real‐time estimation of biomass in Escherichia coli cultivations B Bayer, M von Stosch, M Melcher, M Duerkop, G Striedner Engineering in Life Sciences 20 (1-2), 26-35, 2020 | 18 | 2020 |
Comparison of mechanistic and hybrid modeling approaches for characterization of a CHO cultivation process: Requirements, pitfalls and solution paths B Bayer, M Duerkop, R Pörtner, J Möller Biotechnology journal 18 (1), 2200381, 2023 | 12 | 2023 |
Spike protein antibodies mediate the apparent correlation between SARS-CoV-2 nucleocapsid antibodies and neutralization test results T Perkmann, T Koller, N Perkmann-Nagele, M Klausberger, M Duerkop, ... Microbiology spectrum 9 (1), 10.1128/spectrum. 00218-21, 2021 | 12 | 2021 |
High shear resistance of insect cells: the basis for substantial improvements in cell culture process design F Strobl, M Duerkop, D Palmberger, G Striedner Scientific Reports 11 (1), 9413, 2021 | 10 | 2021 |
Production of full-length SARS-CoV-2 nucleocapsid protein from Escherichia coli optimized by native hydrophobic interaction chromatography hyphenated to multi-angle light … J De Vos, PP Aguilar, C Köppl, A Fischer, C Grünwald-Gruber, M Dürkop, ... Talanta 235, 122691, 2021 | 9 | 2021 |
Hybrid modeling for simultaneous prediction of flux, rejection factor and concentration in two-component crossflow ultrafiltration M Krippl, I Bofarull-Manzano, M Duerkop, A Dürauer Processes 8 (12), 1625, 2020 | 9 | 2020 |
Increasing both specificity and sensitivity of SARS-CoV-2 antibody tests by using an adaptive orthogonal testing approach T Perkmann, T Koller, N Perkmann-Nagele, M Ozsvar-Kozma, D Eyre, ... | 7* | 2020 |
Fundamental insights in early‐stage inclusion body formation J Kopp, B Bayer, C Slouka, G Striedner, M Dürkop, O Spadiut Microbial Biotechnology 16 (5), 893-900, 2023 | 5 | 2023 |
Boost dynamic protocols for producing mammalian biopharmaceuticals with intensified DoE—A practical guide to analyses with OLS and hybrid modeling V Nold, L Junghans, B Bayer, L Bisgen, M Duerkop, R Drerup, B Presser, ... Frontiers in Chemical Engineering 4, 1044245, 2023 | 5 | 2023 |
A comprehensive antigen production and characterisation study for easy-to-implement, specific and quantitative SARS-CoV-2 serotests. EBioMedicine 67: 103348 M Klausberger, M Duerkop, H Haslacher, G Wozniak-Knopp, ... | 5 | 2021 |