Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy EP Kirk, M Sunde, MW Costa, SA Rankin, O Wolstein, ML Castro, ... The American Journal of Human Genetics 81 (2), 280-291, 2007 | 419 | 2007 |
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart FA Stennard, MW Costa, DA Elliott, S Rankin, SJP Haast, D Lai, ... Developmental biology 262 (2), 206-224, 2003 | 374 | 2003 |
Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation FA Stennard, MW Costa, D Lai, C Biben, MB Furtado, MJ Solloway, ... Oxford University Press for The Company of Biologists Limited 132 (10), 2451 …, 2005 | 277 | 2005 |
Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair MB Furtado, MW Costa, EA Pranoto, E Salimova, AR Pinto, NT Lam, ... Circulation research 114 (9), 1422-1434, 2014 | 223 | 2014 |
Dynamic interstitial cell response during myocardial infarction predicts resilience to rupture in genetically diverse mice E Forte, DA Skelly, M Chen, S Daigle, KA Morelli, O Hon, VM Philip, ... Cell reports 30 (9), 3149-3163. e6, 2020 | 163 | 2020 |
Transcriptional regulation of the murine Connexin40 promoter by cardiac factors Nkx2-5, GATA4 and Tbx5 VLF Linhares, NAS Almeida, DC Menezes, DA Elliott, D Lai, EC Beyer, ... Cardiovascular research 64 (3), 402-411, 2004 | 136 | 2004 |
Voltage dependence of macroscopic and unitary currents of gap junction channels formed by mouse connexin50 expressed in rat neuroblastoma cells M Srinivas, M Costa, Y Gao, A Fort, GI Fishman, DC Spray The Journal of Physiology 517 (3), 673-689, 1999 | 129 | 1999 |
NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network DJ Anderson, DI Kaplan, KM Bell, K Koutsis, JM Haynes, RJ Mills, ... Nature communications 9 (1), 1373, 2018 | 113 | 2018 |
Homeodomain factor Nkx2-5 in heart development and disease RP Harvey, D Lai, D Elliott, C Biben, M Solloway, O Prall, F Stennard, ... Cold Spring Harbor symposia on quantitative biology 67, 107-114, 2002 | 100 | 2002 |
Functional Characterization of a Novel Mutation in NKX2-5 Associated With Congenital Heart Disease and Adult-Onset Cardiomyopathy MW Costa, G Guo, O Wolstein, M Vale, ML Castro, L Wang, R Otway, ... Circulation: Cardiovascular Genetics 6 (3), 238-247, 2013 | 99 | 2013 |
Probing transcription factor diffusion dynamics in the living mammalian embryo with photoactivatable fluorescence correlation spectroscopy G Kaur, MW Costa, CM Nefzger, J Silva, JC Fierro-González, JM Polo, ... Nature communications 4 (1), 1637, 2013 | 88 | 2013 |
BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4 MB Furtado, MJ Solloway, VJ Jones, MW Costa, C Biben, O Wolstein, ... Genes & development 22 (21), 3037-3049, 2008 | 85 | 2008 |
GATA4 Mutations in 357 Unrelated Patients with Congenital Heart Malformation TL Butler, G Esposito, GM Blue, AD Cole, MW Costa, LB Waddell, ... Genetic testing and molecular biomarkers 14 (6), 797-802, 2010 | 74 | 2010 |
Transcription factor protein interactomes reveal genetic determinants in heart disease B Gonzalez-Teran, M Pittman, F Felix, R Thomas, D Richmond-Buccola, ... Cell 185 (5), 794-814. e30, 2022 | 54 | 2022 |
The cardiac fibroblast: Origin, identity and role in homeostasis and disease MB Furtado, MW Costa, NA Rosenthal Differentiation 92 (3), 93-101, 2016 | 51 | 2016 |
Effect of oxygen on cardiac differentiation in mouse iPS cells: role of hypoxia inducible factor-1 and Wnt/beta-catenin signaling TL Medley, M Furtado, NT Lam, R Idrizi, D Williams, PJ Verma, M Costa, ... PloS one 8 (11), e80280, 2013 | 51 | 2013 |
Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5 MW Costa, S Lee, MB Furtado, L Xin, DB Sparrow, CG Martinez, ... PloS one 6 (9), e24812, 2011 | 50 | 2011 |
Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy C Choquet, THM Nguyen, P Sicard, E Buttigieg, TT Tran, F Kober, I Varlet, ... PLoS Genetics 14 (7), e1007502, 2018 | 45 | 2018 |
A tyrosine-rich domain within homeodomain transcription factor Nkx2-5 is an essential element in the early cardiac transcriptional regulatory machinery DA Elliott, MJ Solloway, N Wise, C Biben, MW Costa, MB Furtado, ... Oxford University Press for The Company of Biologists Limited 133 (7), 1311-1322, 2006 | 38 | 2006 |
A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels MB Furtado, JC Wilmanns, A Chandran, M Tonta, C Biben, M Eichenlaub, ... Differentiation 91 (1-3), 29-41, 2016 | 32 | 2016 |