Bone marrow–derived stem cells initiate pancreatic regeneration D Hess, L Li, M Martin, S Sakano, D Hill, B Strutt, S Thyssen, DA Gray, ... Nature biotechnology 21 (7), 763-770, 2003 | 885 | 2003 |
The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells FN Karanu, B Murdoch, L Gallacher, DM Wu, M Koremoto, S Sakano, ... The Journal of experimental medicine 192 (9), 1365-1372, 2000 | 577 | 2000 |
Fcα/μ receptor mediates endocytosis of IgM-coated microbes A Shibuya, N Sakamoto, Y Shimizu, K Shibuya, M Osawa, T Hiroyama, ... Nature immunology 1 (5), 441-446, 2000 | 485 | 2000 |
Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling M Nobta, T Tsukazaki, Y Shibata, C Xin, T Moriishi, S Sakano, H Shindo, ... Journal of Biological Chemistry 280 (16), 15842-15848, 2005 | 260 | 2005 |
Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells FN Karanu, B Murdoch, T Miyabayashi, M Ohno, M Koremoto, L Gallacher, ... Blood, The Journal of the American Society of Hematology 97 (7), 1960-1967, 2001 | 229 | 2001 |
Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system A Itoh, T Miyabayashi, M Ohno, S Sakano Molecular brain research 62 (2), 175-186, 1998 | 224 | 1998 |
The association of Notch2 and NF-κB accelerates RANKL-induced osteoclastogenesis H Fukushima, A Nakao, F Okamoto, M Shin, H Kajiya, S Sakano, A Bigas, ... Molecular and cellular biology, 2008 | 199 | 2008 |
Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells T Yamada, H Yamazaki, T Yamane, M Yoshino, H Okuyama, M Tsuneto, ... Blood, The Journal of the American Society of Hematology 101 (6), 2227-2234, 2003 | 158 | 2003 |
A novel Fc receptor for IgA and IgM is expressed on both hematopoietic and non‐hematopoietic tissues N Sakamoto, K Shibuya, Y Shimizu, K Yotsumoto, T Miyabayashi, ... European journal of immunology 31 (5), 1310-1316, 2001 | 138 | 2001 |
Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury T Kobayashi, Y Terada, H Kuwana, H Tanaka, T Okado, M Kuwahara, ... Kidney international 73 (11), 1240-1250, 2008 | 134 | 2008 |
Notch ligands Delta‐like1, Delta‐like4 and Jagged1 differentially regulate activation of peripheral T helper cells S Rutz, B Mordmüller, S Sakano, A Scheffold European journal of immunology 35 (8), 2443-2451, 2005 | 130 | 2005 |
Characterization of a ligand for receptor protein-tyrosine kinase HTK expressed in immature hematopoietic cells. S Sakano, R Serizawa, T Inada, A Iwama, A Itoh, C Kato, Y Shimizu, ... oncogene 13 (4), 813-822, 1996 | 121 | 1996 |
Highly efficient ex vivo expansion of human hematopoietic stem cells using Delta1‐Fc chimeric protein T Suzuki, Y Yokoyama, K Kumano, M Takanashi, S Kozuma, T Takato, ... Stem Cells 24 (11), 2456-2465, 2006 | 114 | 2006 |
A role of EphB4 receptor and its ligand, ephrin-B2, in erythropoiesis S Suenobu, N Takakura, T Inada, Y Yamada, H Yuasa, XQ Zhang, ... Biochemical and biophysical research communications 293 (3), 1124-1131, 2002 | 101 | 2002 |
Differentiation-suppressive polypeptide S Sakano, A Itoh US Patent 6,337,387, 2002 | 96 | 2002 |
Molecular cloning of a novel non-receptor tyrosine kinase, HYL (hematopoietic consensus tyrosine-lacking kinase). S Sakano, A Iwama, J Inazawa, T Ariyama, M Ohno, T Suda Oncogene 9 (4), 1155-1161, 1994 | 85 | 1994 |
Diverse effects of the Notch ligands Jagged1 and Delta1 on the growth and differentiation of primary acute myeloblastic leukemia cells S Tohda, H Kogoshi, N Murakami, S Sakano, N Nara Experimental hematology 33 (5), 558-563, 2005 | 71 | 2005 |
Differentiation inhibitory agent S Sakano US Patent 6,664,098, 2003 | 68 | 2003 |
Establishment of a novel B-cell lymphoma cell line with suppressed growth by gamma-secretase inhibitors S Tohda, T Sato, H Kogoshi, L Fu, S Sakano, N Nara Leukemia research 30 (11), 1385-1390, 2006 | 60 | 2006 |
Differential response of primitive human CD34− and CD34+ hematopoietic cells to the Notch ligand Jagged-1 FN Karanu, L Yuefei, L Gallacher, S Sakano, M Bhatia Leukemia 17 (7), 1366-1374, 2003 | 56 | 2003 |