Design and Synthesis of New Tetrazolyl- and Carboxy-biphenylylmethyl-quinazolin-4-one Derivatives as Angiotensin II AT1 Receptor Antagonists MAH Ismail, S Barker, DA Abou El Ella, KAM Abouzid, RA Toubar, ... Journal of medicinal chemistry 49 (5), 1526-1535, 2006 | 142 | 2006 |
1-Piperazinylphthalazines as potential VEGFR-2 inhibitors and anticancer agents: synthesis and in vitro biological evaluation SM Abou-Seri, WM Eldehna, MM Ali, DA Abou El Ella European journal of medicinal chemistry 107, 165-179, 2016 | 127 | 2016 |
Molecular modeling study and synthesis of novel pyrrolo [2, 3-d] pyrimidines and pyrrolotriazolopyrimidines of expected antitumor and radioprotective activities DA Abou El Ella, MM Ghorab, E Noaman, HI Heiba, AI Khalil Bioorganic & medicinal chemistry 16 (5), 2391-2402, 2008 | 100 | 2008 |
Recent advances in 4-aminoquinazoline based scaffold derivatives targeting EGFR kinases as anticancer agents RSM Ismail, NSM Ismail, S Abuserii, DA Abou El Ella Future Journal of Pharmaceutical Sciences 2 (1), 9-19, 2016 | 93 | 2016 |
Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1 … WM Eldehna, SM Abou-Seri, AM El Kerdawy, RR Ayyad, AM Hamdy, ... European Journal of Medicinal Chemistry 113, 50-62, 2016 | 86 | 2016 |
Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII WM Eldehna, M Fares, M Ceruso, HA Ghabbour, SM Abou-Seri, ... European journal of medicinal chemistry 110, 259-266, 2016 | 84 | 2016 |
Design, synthesis and biological evaluation of type-II VEGFR-2 inhibitors based on quinoxaline scaffold MI Shahin, DA Abou El Ella, NSM Ismail, KAM Abouzid Bioorganic Chemistry 56, 16-26, 2014 | 78 | 2014 |
Design, synthesis, mechanistic studies and in silico ADME predictions of benzimidazole derivatives as novel antifungal agents MM Morcoss, MN El Shimaa, RA Ibrahem, HM Abdel-Rahman, ... Bioorganic chemistry 101, 103956, 2020 | 74 | 2020 |
Quinoxaline‐based scaffolds targeting tyrosine kinases and their potential anticancer activity AMS El Newahie, NSM Ismail, DA Abou El Ella, KAM Abouzid Archiv der Pharmazie 349 (5), 309-326, 2016 | 69 | 2016 |
Thieno [2, 3-d] pyrimidine based derivatives as kinase inhibitors and anticancer agents EZ Elrazaz, RAT Serya, NSM Ismail, DA Abou El Ella, KAM Abouzid Future Journal of Pharmaceutical Sciences 1 (2), 33-41, 2015 | 69 | 2015 |
Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular docking WM Eldehna, M Fares, HS Ibrahim, MH Aly, S Zada, MM Ali, ... European journal of medicinal chemistry 100, 89-97, 2015 | 62 | 2015 |
Pyrazolo [3, 4-d] pyrimidine based scaffold derivatives targeting kinases as anticancer agents NSM Ismail, EMH Ali, DA Ibrahim, RAT Serya, DA Abou El Ella Future Journal of Pharmaceutical Sciences 2 (1), 20-30, 2016 | 59 | 2016 |
Aromatase inhibitors and apoptotic inducers: Design, synthesis, anticancer activity and molecular modeling studies of novel phenothiazine derivatives carrying sulfonamide … MM Ghorab, MS Alsaid, N Samir, GA Abdel-Latif, AM Soliman, FA Ragab, ... European journal of medicinal chemistry 134, 304-315, 2017 | 57 | 2017 |
Design and synthesis of new quinoxaline derivatives as anticancer agents and apoptotic inducers AMS El Newahie, YM Nissan, NSM Ismail, DA Abou El Ella, SM Khojah, ... Molecules 24 (6), 1175, 2019 | 54 | 2019 |
Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII DA Ibrahim, DS Lasheen, MY Zaky, AW Ibrahim, D Vullo, M Ceruso, ... Bioorganic & medicinal chemistry 23 (15), 4989-4999, 2015 | 53 | 2015 |
Molecular modeling study and synthesis of quinazolinone-arylpiperazine derivatives as α1-adrenoreceptor antagonists SM Abou-Seri, K Abouzid, DA Abou El Ella European Journal of Medicinal Chemistry 46 (2), 647-658, 2011 | 53 | 2011 |
Novel series of 6-(2-substitutedacetamido)-4-anilinoquinazolines as EGFR-ERK signal transduction inhibitors in MCF-7 breast cancer cells RSM Ismail, SM Abou-Seri, WM Eldehna, NSM Ismail, SM Elgazwi, ... European Journal of Medicinal Chemistry 155, 782-796, 2018 | 52 | 2018 |
Analogue based drug design, synthesis, molecular docking and anticancer evaluation of novel chromene sulfonamide hybrids as aromatase inhibitors and apoptosis enhancers MM Ghorab, MS Alsaid, GH Al-Ansary, GA Abdel-Latif, DA Abou El Ella European journal of medicinal chemistry 124, 946-958, 2016 | 50 | 2016 |
Lonazolac analogues: molecular modeling, synthesis, and in vivo anti-inflammatory activity MAH Ismail, J Lehmann, DA Abou El Ella, A Albohy, KAM Abouzid Medicinal chemistry research 18, 725-744, 2009 | 47 | 2009 |
Novel quinoline-3-carboxamides (Part 2): Design, optimization and synthesis of quinoline based scaffold as EGFR inhibitors with potent anticancer activity RM Aly, RAT Serya, AM El-Motwally, A Esmat, S Abbas, DA Abou El Ella Bioorganic Chemistry 75, 368-392, 2017 | 45 | 2017 |