Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone SM Kerfoot, G Yaari, JR Patel, KL Johnson, DG Gonzalez, SH Kleinstein, ... Immunity 34 (6), 947-960, 2011 | 570 | 2011 |
Recoded organisms engineered to depend on synthetic amino acids AJ Rovner, AD Haimovich, SR Katz, Z Li, MW Grome, BM Gassaway, ... Nature 518 (7537), 89-93, 2015 | 372 | 2015 |
Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids RW Martin, BJ Des Soye, YC Kwon, J Kay, RG Davis, PM Thomas, ... Nature communications 9 (1), 1203, 2018 | 216 | 2018 |
Multilayered genetic safeguards limit growth of microorganisms to defined environments RR Gallagher, JR Patel, AL Interiano, AJ Rovner, FJ Isaacs Nucleic acids research 43 (3), 1945-1954, 2015 | 141 | 2015 |
Repurposing the translation apparatus for synthetic biology B Des Soye, JR Patel, FJ Isaacs, J Michael J Current Opinion in Chemical Biology 2, 83-90, 2015 | 92 | 2015 |
A mechanistic model for colibactin-induced genotoxicity AR Healy, H Nikolayevskiy, JR Patel, JM Crawford, SB Herzon Journal of the American Chemical Society 138 (48), 15563-15570, 2016 | 82 | 2016 |
Nonredundant roles of IL-21 and IL-4 in the phased initiation of germinal center B cells and subsequent self-renewal transitions DG Gonzalez, CM Cote, JR Patel, CB Smith, Y Zhang, KM Nickerson, ... The Journal of Immunology 201 (12), 3569-3579, 2018 | 81 | 2018 |
The role of orthogonality in genetic code expansion P Arranz-Gibert, JR Patel, FJ Isaacs Life 9 (3), 58, 2019 | 31 | 2019 |
Model colibactins exhibit human cell genotoxicity in the absence of host bacteria EE Shine, M Xue, JR Patel, AR Healy, YV Surovtseva, SB Herzon, ... ACS chemical biology 13 (12), 3286-3293, 2018 | 26 | 2018 |
β-Lactam biotransformations activate innate immunity J Oh, J Patel, HB Park, JM Crawford The Journal of organic chemistry 83 (13), 7173-7179, 2018 | 24 | 2018 |
Cross-kingdom expression of synthetic genetic elements promotes discovery of metabolites in the human microbiome JR Patel, J Oh, S Wang, JM Crawford, FJ Isaacs Cell 185 (9), 1487-1505. e14, 2022 | 22 | 2022 |
Microbiota-regulated outcomes of human cancer immunotherapy via the PD-1/PD-L1 axis J Patel, JM Crawford Biochemistry 57 (6), 901-903, 2018 | 14 | 2018 |
Dimeric stilbene antibiotics target the bacterial cell wall in drug-resistant gram-positive pathogens TN Goddard, J Patel, HB Park, JM Crawford Biochemistry 59 (21), 1966-1971, 2020 | 11 | 2020 |
Compositions and methods for biocontainment of microorganisms FJ Isaacs, R Gallagher, J Patel, A Rovner US Patent 11,408,007, 2022 | 2 | 2022 |
Anti-bacterial stilbene derivatives and methods of use J Crawford, T Goddard, HB Park, J Patel | | 2020 |
Inter-follicular germinal center B cell and T follicular helper cell development precedes follicular Tfh maintenance (63.23) S Kerfoot, G Yaari, J Patel, K Johnson, D Gonzalez, S Kleinstein, ... The Journal of Immunology 186 (1_Supplement), 63.23-63.23, 2011 | | 2011 |
Yale iGEM 2015 Research Summary AHL Saydjari, N Ma, J Patel, CE Perez, S Dellaporta, FJ Isaacs | | |