Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention M Inouye, G Abraham, CP Nelson, AM Wood, MJ Sweeting, F Dudbridge, ... Journal of the American College of Cardiology 72 (16), 1883-1893, 2018 | 634 | 2018 |
Towards clinical utility of polygenic risk scores SA Lambert, G Abraham, M Inouye Human molecular genetics 28 (R2), R133-R142, 2019 | 407 | 2019 |
Genomic prediction of coronary heart disease G Abraham, AS Havulinna, OG Bhalala, SG Byars, AM De Livera, ... European heart journal 37 (43), 3267-3278, 2016 | 333 | 2016 |
Fast Principal Component Analysis of Large-Scale Genome-Wide Data G Abraham, M Inouye PloS one 9 (4), e93766, 2014 | 314 | 2014 |
FlashPCA2: principal component analysis of Biobank-scale genotype datasets G Abraham, Y Qiu, M Inouye Bioinformatics 33 (17), 2776-2778, 2017 | 309 | 2017 |
The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation SA Lambert, L Gil, S Jupp, SC Ritchie, Y Xu, A Buniello, A McMahon, ... Nature Genetics, 1-6, 2021 | 293 | 2021 |
The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection SC Ritchie, P Würtz, AP Nath, G Abraham, AS Havulinna, LG Fearnley, ... Cell Systems 1 (4), 293-301, 2015 | 197 | 2015 |
Short-term forecasting of emergency inpatient flow G Abraham, GB Byrnes, CA Bain IEEE Transactions on Information Technology in Biomedicine 13 (3), 380-388, 2009 | 147 | 2009 |
Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke G Abraham, R Malik, E Yonova-Doing, A Salim, T Wang, J Danesh, ... Nature Communications 10 (1), 1-10, 2019 | 142 | 2019 |
Performance and Robustness of Penalized and Unpenalized Methods for Genetic Prediction of Complex Human Disease G Abraham, A Kowalczyk, J Zobel, M Inouye Genetic Epidemiology 37 (2), 184-195, 2013 | 133 | 2013 |
Genomic risk prediction of complex human disease and its clinical application G Abraham, M Inouye Current Opinion in Genetics & Development 33, 10-16, 2015 | 127 | 2015 |
Accurate and robust genomic prediction of celiac disease using statistical learning G Abraham, JA Tye-Din, OG Bhalala, A Kowalczyk, J Zobel, M Inouye PLoS Genetics 10 (2), e1004137, 2014 | 121 | 2014 |
Prediction of breast cancer prognosis using gene set statistics provides signature stability and biological context G Abraham, A Kowalczyk, S Loi, I Haviv, J Zobel BMC bioinformatics 11 (1), 277, 2010 | 103 | 2010 |
Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses L Sun, L Pennells, S Kaptoge, CP Nelson, SC Ritchie, G Abraham, ... PLoS medicine 18 (1), e1003498, 2021 | 96 | 2021 |
Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy SG Byars, QQ Huang, LA Gray, A Bakshi, S Ripatti, G Abraham, ... PLOS Genetics 13 (6), e1006328, 2017 | 65 | 2017 |
A Scalable Permutation Approach Reveals Replication and Preservation Patterns of Network Modules in Large Datasets SC Ritchie, S Watts, LG Fearnley, KE Holt, G Abraham, M Inouye Cell Systems 3 (1), 71-82, 2016 | 56 | 2016 |
An interaction map of circulating metabolites, immune gene networks, and their genetic regulation AP Nath, SC Ritchie, SG Byars, LG Fearnley, AS Havulinna, A Joensuu, ... Genome Biology 18 (1), 146, 2017 | 44 | 2017 |
SparSNP: Fast and memory-efficient analysis of all SNPs for phenotype prediction G Abraham, A Kowalczyk, J Zobel, M Inouye BMC bioinformatics 13 (1), 88, 2012 | 43 | 2012 |
Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases SC Ritchie, SA Lambert, M Arnold, SM Teo, S Lim, P Scepanovic, ... Nature Metabolism, 1-8, 2021 | 41 | 2021 |
Genomic prediction of celiac disease targeting HLA-positive individuals G Abraham, A Rohmer, JA Tye-Din, M Inouye Genome Medicine 7, 72, 2015 | 27 | 2015 |