| The nuclear receptor ESRRA protects from kidney disease by coupling metabolism and differentiation P Dhillon, J Park, CH Del Pozo, L Li, T Doke, S Huang, J Zhao, HM Kang, ... Cell metabolism 33 (2), 379-394. e8, 2021 | 103 | 2021 |
| Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease H Liu, T Doke, D Guo, X Sheng, Z Ma, J Park, HMT Vy, GN Nadkarni, ... Nature genetics 54 (7), 950-962, 2022 | 71 | 2022 |
| Molecular pathways that drive diabetic kidney disease S Mohandes, T Doke, H Hu, D Mukhi, P Dhillon, K Susztak The Journal of clinical investigation 133 (4), 2023 | 69 | 2023 |
| Single-cell analysis highlights differences in druggable pathways underlying adaptive or fibrotic kidney regeneration MS Balzer, T Doke, YW Yang, DL Aldridge, H Hu, H Mai, D Mukhi, Z Ma, ... Nature Communications 13 (1), 4018, 2022 | 58 | 2022 |
| NAD+ flux is maintained in aged mice despite lower tissue concentrations MR McReynolds, K Chellappa, E Chiles, C Jankowski, Y Shen, L Chen, ... Cell systems 12 (12), 1160-1172. e4, 2021 | 57 | 2021 |
| Transcriptome-wide association analysis identifies DACH1 as a kidney disease risk gene that contributes to fibrosis T Doke, S Huang, C Qiu, H Liu, Y Guan, H Hu, Z Ma, J Wu, Z Miao, ... The Journal of clinical investigation 131 (10), 2021 | 54 | 2021 |
| Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis T Doke, A Abedini, DL Aldridge, YW Yang, J Park, CM Hernandez, ... Nature immunology 23 (6), 947-959, 2022 | 41 | 2022 |
| The multifaceted role of kidney tubule mitochondrial dysfunction in kidney disease development T Doke, K Susztak Trends in cell biology 32 (10), 841-853, 2022 | 39 | 2022 |
| Aging-associated renal disease in mice is fructokinase dependent CA Roncal-Jimenez, T Ishimoto, MA Lanaspa, T Milagres, AA Hernando, ... American Journal of Physiology-Renal Physiology 311 (4), F722-F730, 2016 | 35 | 2016 |
| DACH1 protects podocytes from experimental diabetic injury and modulates PTIP-H3K4Me3 activity A Cao, J Li, M Asadi, JM Basgen, B Zhu, Z Yi, S Jiang, T Doke, ... The Journal of clinical investigation 131 (10), 2021 | 25 | 2021 |
| Lacking ketohexokinase-A exacerbates renal injury in streptozotocin-induced diabetic mice T Doke, T Ishimoto, T Hayasaki, S Ikeda, M Hasebe, A Hirayama, T Soga, ... Metabolism 85, 161-170, 2018 | 21 | 2018 |
| Comprehensive dipeptide profiling and quantitation by capillary electrophoresis and liquid chromatography coupled with tandem mass spectrometry H Ozawa, A Hirayama, T Ishikawa, R Kudo, M Maruyama, F Shoji, T Doke, ... Analytical Chemistry 92 (14), 9799-9806, 2020 | 20 | 2020 |
| NAD+ precursor supplementation prevents mtRNA/RIG-I-dependent inflammation during kidney injury T Doke, S Mukherjee, D Mukhi, P Dhillon, A Abedini, JG Davis, ... Nature metabolism 5 (3), 414-430, 2023 | 19 | 2023 |
| Fructose increases the activity of sodium hydrogen exchanger in renal proximal tubules that is dependent on ketohexokinase T Hayasaki, T Ishimoto, T Doke, A Hirayama, T Soga, K Furuhashi, N Kato, ... The Journal of Nutritional Biochemistry 71, 54-62, 2019 | 16 | 2019 |
| Genome-wide association studies identify the role of caspase-9 in kidney disease T Doke, S Huang, C Qiu, X Sheng, M Seasock, H Liu, Z Ma, M Palmer, ... Science advances 7 (45), eabi8051, 2021 | 15 | 2021 |
| Unbiased human kidney tissue proteomics identifies matrix metalloproteinase 7 as a kidney disease biomarker D Hirohama, A Abedini, S Moon, A Surapaneni, ST Dillon, A Vassalotti, ... Journal of the American Society of Nephrology 34 (7), 1279-1291, 2023 | 7 | 2023 |
| Long non-coding RNA lnc-CHAF1B-3 promotes renal interstitial fibrosis by regulating EMT-related genes in renal proximal tubular cells K Imai, T Ishimoto, T Doke, T Tsuboi, Y Watanabe, K Katsushima, ... Molecular Therapy-Nucleic Acids 31, 139-150, 2023 | 7 | 2023 |
| Post-transplant membranous nephropathy associated with chronic active antibody-mediated rejection and Hepatitis C infection after deceased donor renal transplantation T Doke, W Sato, K Takahashi, H Hayashi, S Koide, H Sasaki, M Kusaka, ... Internal Medicine 55 (4), 375-380, 2016 | 4 | 2016 |
| ACSS2 gene variants determine kidney disease risk by controlling de novo lipogenesis in kidney tubules D Mukhi, L Li, H Liu, T Doke, LP Kolligundla, E Ha, K Kloetzer, A Abedini, ... The Journal of Clinical Investigation 134 (4), 2024 | 2 | 2024 |
| Single-cell transcriptomics and chromatin accessibility profiling elucidate the kidney-protective mechanism of mineralocorticoid receptor antagonists A Abedini, A Sánchez-Navaro, J Wu, KA Klötzer, Z Ma, B Poudel, T Doke, ... The Journal of Clinical Investigation 134 (1), 2024 | | 2024 |
Katalin SusztakUniversity of Pennsylvania在 pennmedicine.upenn.edu 的电子邮件经过验证
