Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism FK Satterstrom, JA Kosmicki, J Wang, MS Breen, S De Rubeis, JY An, ... Cell 180 (3), 568-584. e23, 2020 | 1719 | 2020 |
Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder ET Lim, M Uddin, S De Rubeis, Y Chan, AS Kamumbu, X Zhang, ... Nature neuroscience 20 (9), 1217-1224, 2017 | 269 | 2017 |
Comparative analyses of copy-number variation in autism spectrum disorder and schizophrenia reveal etiological overlap and biological insights I Kushima, B Aleksic, M Nakatochi, T Shimamura, T Okada, Y Uno, ... Cell reports 24 (11), 2838-2856, 2018 | 214 | 2018 |
Genome-wide association study of schizophrenia in a Japanese population M Ikeda, B Aleksic, Y Kinoshita, T Okochi, K Kawashima, I Kushima, Y Ito, ... Biological psychiatry 69 (5), 472-478, 2011 | 193 | 2011 |
Effect of intranasal oxytocin on the core social symptoms of autism spectrum disorder: a randomized clinical trial H Yamasue, T Okada, T Munesue, M Kuroda, T Fujioka, Y Uno, ... Molecular psychiatry 25 (8), 1849-1858, 2020 | 163 | 2020 |
Integrative analyses of de novo mutations provide deeper biological insights into autism spectrum disorder A Takata, N Miyake, Y Tsurusaki, R Fukai, S Miyatake, E Koshimizu, ... Cell reports 22 (3), 734-747, 2018 | 162 | 2018 |
High-resolution copy number variation analysis of schizophrenia in Japan I Kushima, B Aleksic, M Nakatochi, T Shimamura, T Shiino, A Yoshimi, ... Molecular psychiatry 22 (3), 430-440, 2017 | 132 | 2017 |
Genome-wide association study detected novel susceptibility genes for schizophrenia and shared trans-populations/diseases genetic effect M Ikeda, A Takahashi, Y Kamatani, Y Momozawa, T Saito, K Kondo, ... Schizophrenia bulletin 45 (4), 824-834, 2019 | 125 | 2019 |
Resequencing and Association Analysis of the KALRN and EPHB1 Genes And Their Contribution to Schizophrenia Susceptibility I Kushima, Y Nakamura, B Aleksic, M Ikeda, Y Ito, T Shiino, T Okochi, ... Schizophrenia bulletin 38 (3), 552-560, 2012 | 100 | 2012 |
Rare genetic variants in CX3CR1 and their contribution to the increased risk of schizophrenia and autism spectrum disorders K Ishizuka, Y Fujita, T Kawabata, H Kimura, Y Iwayama, T Inada, ... Translational psychiatry 7 (8), e1184-e1184, 2017 | 71 | 2017 |
Parental origin of interstitial duplications at 15q11. 2-q13. 3 in schizophrenia and neurodevelopmental disorders AR Isles, A Ingason, C Lowther, J Walters, M Gawlick, G Stöber, E Rees, ... PLoS genetics 12 (5), e1005993, 2016 | 71 | 2016 |
Resequencing and association analysis of six PSD-95-related genes as possible susceptibility genes for schizophrenia and autism spectrum disorders J Xing, H Kimura, C Wang, K Ishizuka, I Kushima, Y Arioka, A Yoshimi, ... Scientific reports 6 (1), 1-8, 2016 | 67 | 2016 |
Common Variants in MAGI2 Gene Are Associated with Increased Risk for Cognitive Impairment in Schizophrenic Patients T Koide, M Banno, B Aleksic, S Yamashita, T Kikuchi, K Kohmura, ... PloS one 7 (5), e36836, 2012 | 59 | 2012 |
Rare loss of function mutations in N-methyl-d-aspartate glutamate receptors and their contributions to schizophrenia susceptibility Y Yu, Y Lin, Y Takasaki, C Wang, H Kimura, J Xing, K Ishizuka, M Toyama, ... Translational psychiatry 8 (1), 12, 2018 | 56 | 2018 |
Single-neuron and genetic correlates of autistic behavior in macaque K Yoshida, Y Go, I Kushima, A Toyoda, A Fujiyama, H Imai, N Saito, A Iriki, ... Science Advances 2 (9), e1600558, 2016 | 50 | 2016 |
In vitro modeling of the bipolar disorder and schizophrenia using patient-derived induced pluripotent stem cells with copy number variations of PCDH15 and RELN T Ishii, M Ishikawa, K Fujimori, T Maeda, I Kushima, Y Arioka, D Mori, ... Eneuro 6 (5), 2019 | 49 | 2019 |
Novel genes for autism implicate both excitatory and inhibitory cell lineages in risk FK Satterstrom, JA Kosmicki, J Wang, MS Breen, SD Rubeis, JY An, ... BioRxiv, 484113, 2018 | 49 | 2018 |
Trends in big data analyses by multicenter collaborative translational research in psychiatry T Onitsuka, Y Hirano, K Nemoto, N Hashimoto, I Kushima, D Koshiyama, ... Psychiatry and clinical neurosciences 76 (1), 1-14, 2022 | 44 | 2022 |
ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk M Sekiguchi, A Sobue, I Kushima, C Wang, Y Arioka, H Kato, A Kodama, ... Translational psychiatry 10 (1), 247, 2020 | 43 | 2020 |
Comprehensive analysis of a novel mouse model of the 22q11. 2 deletion syndrome: a model with the most common 3.0-Mb deletion at the human 22q11. 2 locus R Saito, M Koebis, T Nagai, K Shimizu, J Liao, B Wulaer, Y Sugaya, ... Translational psychiatry 10 (1), 35, 2020 | 43 | 2020 |