A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 J Hampe, A Franke, P Rosenstiel, A Till, M Teuber, K Huse, M Albrecht, ... Nature genetics 39 (2), 207-211, 2007 | 2224 | 2007 |
Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease SJ Ott, M Musfeldt, DF Wenderoth, J Hampe, O Brant, UR Fölsch, ... Gut 53 (5), 685-693, 2004 | 1383 | 2004 |
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations J Hampe, A Cuthbert, PJP Croucher, MM Mirza, S Mascheretti, S Fisher, ... The Lancet 357 (9272), 1925-1928, 2001 | 1376 | 2001 |
Activation of nuclear factor κB in inflammatory bowel disease S Schreiber, S Nikolaus, J Hampe Gut 42 (4), 477-484, 1998 | 942 | 1998 |
The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease AP Cuthbert, SA Fisher, MM Mirza, K King, J Hampe, PJP Croucher, ... Gastroenterology 122 (4), 867-874, 2002 | 903 | 2002 |
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity S Wahl, A Drong, B Lehne, M Loh, WR Scott, S Kunze, PC Tsai, JS Ried, ... Nature 541 (7635), 81-86, 2017 | 757 | 2017 |
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21 A Tenesa, SM Farrington, JGD Prendergast, ME Porteous, M Walker, ... Nature genetics 40 (5), 631-637, 2008 | 668 | 2008 |
Obesity accelerates epigenetic aging of human liver S Horvath, W Erhart, M Brosch, O Ammerpohl, W von Schönfels, M Ahrens, ... Proceedings of the National Academy of Sciences 111 (43), 15538-15543, 2014 | 655 | 2014 |
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23. 3 IPM Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, K Howarth, ... Nature genetics 40 (5), 623-630, 2008 | 641 | 2008 |
Genetic variation in DLG5 is associated with inflammatory bowel disease M Stoll, B Corneliussen, CM Costello, GH Waetzig, B Mellgard, WA Koch, ... Nature genetics 36 (5), 476-480, 2004 | 604 | 2004 |
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer L Carvajal-Carmona, K Howarth, E Jaeger, SL Spain, A Walther, ... Nature genetics 40 (12), 1426-1435, 2008 | 598 | 2008 |
Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study J Hampe, J Grebe, S Nikolaus, C Solberg, PJP Croucher, S Mascheretti, ... The Lancet 359 (9318), 1661-1665, 2002 | 527 | 2002 |
Sarcoidosis is associated with a truncating splice site mutation in BTNL2 R Valentonyte, J Hampe, K Huse, P Rosenstiel, M Albrecht, A Stenzel, ... Nature genetics 37 (4), 357-364, 2005 | 521 | 2005 |
A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis S Buch, F Stickel, E Trepo, M Way, A Herrmann, HD Nischalke, M Brosch, ... Nature genetics 47 (12), 1443-1448, 2015 | 470 | 2015 |
DNA methylation analysis in nonalcoholic fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery M Ahrens, O Ammerpohl, W von Schönfels, J Kolarova, S Bens, T Itzel, ... Cell metabolism 18 (2), 296-302, 2013 | 448 | 2013 |
A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort J Hampe, S Schreiber, SH Shaw, KF Lau, S Bridger, AJS Macpherson, ... The American journal of human genetics 64 (3), 808-816, 1999 | 442 | 1999 |
Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease SJ Ott, NE El Mokhtari, M Musfeldt, S Hellmig, S Freitag, A Rehman, ... Circulation 113 (7), 929-937, 2006 | 426 | 2006 |
Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study JC Chambers, M Loh, B Lehne, A Drong, J Kriebel, V Motta, S Wahl, ... The lancet Diabetes & endocrinology 3 (7), 526-534, 2015 | 418 | 2015 |
Single base‐pair substitutions in exon–intron junctions of human genes: nature, distribution, and consequences for mRNA splicing M Krawczak, NST Thomas, B Hundrieser, M Mort, M Wittig, J Hampe, ... Human mutation 28 (2), 150-158, 2007 | 404 | 2007 |
A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease S Buch, C Schafmayer, H Völzke, C Becker, A Franke, ... Nature genetics 39 (8), 995-999, 2007 | 388 | 2007 |