作者
Max Lam, Jimmy Lee, Attilio Rapisarda, Yuen Mei See, Zixu Yang, Sara-Ann Lee, Nur Amirah Abdul-Rashid, Michael Kraus, Mythily Subramaniam, Siow-Ann Chong, Richard SE Keefe
发表日期
2018/9/1
期刊
JAMA psychiatry
卷号
75
期号
9
页码范围
929-939
出版商
American Medical Association
简介
Importance
Cognitive deficits are a key feature of risk for psychosis. Longitudinal changes in cognitive architecture may be associated with the social and occupational functioning in young people.
Objectives
To examine longitudinal profiles of cognition in individuals at ultrahigh risk (UHR) for psychosis, compared with healthy controls, and to investigate the association of cognition with functioning.
Design, Setting, and Participants
This study has a multiple-group prospective design completed in 24 months and was conducted from January 1, 2009, to November 11, 2012, as part of the Longitudinal Youth at-Risk Study conducted in Singapore. Participants either were recruited from psychiatric outpatient clinics, educational institutions, and community mental health agencies or self-referred. Follow-up assessments were performed every 6 months for 2 years or until conversion to psychosis. Individuals with medical …
学术搜索中的文章
M Lam, J Lee, A Rapisarda, YM See, Z Yang, SA Lee… - JAMA psychiatry, 2018