作者
Cathryn M Lewis, Evangelos Vassos
发表日期
2017/12
期刊
Genome medicine
卷号
9
页码范围
1-3
出版商
BioMed Central
简介
Editorial summary
Genome-wide association studies have made strides in identifying common variation associated with disease. The modest effect sizes preclude risk prediction based on single genetic variants, but polygenic risk scores that combine thousands of variants show some predictive ability across a range of complex traits and diseases, including neuropsychiatric disorders. Here, we consider the potential for translation to clinical use.
学术搜索中的文章
CM Lewis, E Vassos - Genome medicine, 2017