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In this study, we make use of brain activation data to investigate the perceptual plausibility of a visual and an auditory model for visual and auditory saliency in video processing. These models have already been successfully employed in a number of applications. In addition, we experiment with parameters, modifications and suitable fusion schemes. As part of this work, fMRI data from complex video stimuli were collected, on which we base our analysis and results. The core part of the analysis involves the use of well-established methods for the manipulation of fMRI data and the examination of variability across brain responses of different individuals. Our results indicate a success in confirming the value of these saliency models in terms of perceptual plausibility.