More than 18 million Americans currently have diabetes mellitus. The economic and human
cost of the disease is devastating. In the United States, diabetes is the most common cause …

Although the idea of preventing type 2 diabetes has been articulated since the discovery of
insulin, only in the past decade have clinical trials demonstrated that diabetes can be …

Background: Lifestyle modification can forestall diabetes in high-risk people, but the long-
term cost-effectiveness is uncertain. Objective: To estimate the effects of the lifestyle …

Many large public health problems and epidemics have been overcome by acting on much
less evidence than we have for preventing type 2 diabetes. Therefore, we should act as if …

Objective: Translating lessons from clinical trials on the prevention or delay of type 2
diabetes to populations in nonstudy settings remains a challenge. The purpose of this paper …

Background: The Diabetes Prevention Program (DPP) demonstrated that interventions can
delay or prevent the development of type 2 diabetes. Objective: To estimate the lifetime cost …

What's Preventing Us from Preventing Type 2 Diabetes? | New England Journal of Medicine Skip
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Background: The effect of multifaceted lifestyle interventions on clinically oriented outcomes
across a spectrum of metabolic risk factors and abnormal glucose is unclear. Purpose: To …

Background Lifestyle interventions produce short-term improvements in glycemia and
cardiovascular disease (CVD) risk factors in individuals with type 2 diabetes mellitus, but no …

Background Type 2 diabetes mellitus is increasingly common, primarily because of
increases in the prevalence of a sedentary lifestyle and obesity. Whether type 2 diabetes …