[PDF][PDF] Virus like particles as immunogens and universal nanocarriers

A Naskalska, K Pyrć - 2015 - ruj.uj.edu.pl
Over the last two decades virus‑like particles (VLPs) have become an important tool in
biomedical research and medicine. VLPs are multi‑protein structures that resemble viable …

Virus engineering: functionalization and stabilization

MG Mateu - Protein Engineering, Design & Selection, 2011 - academic.oup.com
Chemically and/or genetically engineered viruses, viral capsids and viral-like particles carry
the promise of important and diverse applications in biomedicine, biotechnology and …

Platforms, advances, and technical challenges in virus-like particles-based vaccines

R Gupta, K Arora, SS Roy, A Joseph… - Frontiers in …, 2023 - frontiersin.org
Viral infectious diseases threaten human health and global stability. Several vaccine
platforms, such as DNA, mRNA, recombinant viral vectors, and virus-like particle-based …

The application of virus-like particles as vaccines and biological vehicles

D Yan, YQ Wei, HC Guo, SQ Sun - Applied microbiology and …, 2015 - Springer
Virus-like particles (VLPs) can be spontaneously self-assembled by viral structural proteins
under appropriate conditions in vitro while excluding the genetic material and potential …

Construction and characterization of virus-like particles: a review

A Zeltins - Molecular biotechnology, 2013 - Springer
Over the last three decades, virus-like particles (VLPs) have evolved to become a widely
accepted technology, especially in the field of vaccinology. In fact, some VLP-based …

Engineering virus-like particles as vaccine platforms

KM Frietze, DS Peabody, B Chackerian - Current opinion in virology, 2016 - Elsevier
Highlights•VLP have been engineered to improve their utility as vaccine platforms.•Targeted
engineering of VLPs has enhanced immunogenicity, stability, and versatility.•Predictive …

Virus-like particles as nanocarriers for intracellular delivery of biomolecules and compounds

J He, L Yu, X Lin, X Liu, Y Zhang, F Yang, W Deng - Viruses, 2022 - mdpi.com
Virus-like particles (VLPs) are nanostructures assemble from viral proteins. Besides widely
used for vaccine development, VLPs have also been explored as nanocarriers for cargo …

[图书][B] Virus-like particles: a comprehensive guide

P Pumpens, P Pushko - 2022 - books.google.com
This book represents the first complete and systematic guide to the virus-like particles
(VLPs) and their applications as vaccines, therapeutic tools, nanomaterials, and …

Development of virus-like particle technology from small highly symmetric to large complex virus-like particle structures

P Pushko, P Pumpens, E Grens - Intervirology, 2013 - karger.com
Virus-like particle (VLP) technology is a promising approach for the construction of novel
vaccines, diagnostic tools, and gene therapy vectors. Initially, VLPs were primarily derived …

Viruses as self-assembled nanocontainers for encapsulation of functional cargoes

Y Wu, H Yang, HJ Shin - Korean Journal of Chemical Engineering, 2013 - Springer
Viruses naturally exhibit an incredible variety of sophisticated nanostructures, which makes
them ideal biological building blocks for nanoengineered material research. By mimicking …