Recent progress on the versatility of virus-like particles

C Qian, X Liu, Q Xu, Z Wang, J Chen, T Li, Q Zheng… - Vaccines, 2020 - mdpi.com
Virus-like particles (VLPs) are multimeric nanostructures composed of one or more structural
proteins of a virus in the absence of genetic material. Having similar morphology to natural …

Exploiting virus-like particles as innovative vaccines against emerging viral infections

H Jeong, BL Seong - Journal of Microbiology, 2017 - Springer
Emerging viruses pose a major threat to humans and livestock with global public health and
economic burdens. Vaccination remains an effective tool to reduce this threat, and yet, the …

Viral nanoparticles: Current advances in design and development

SS Arul, B Balakrishnan, SS Handanahal… - Biochimie, 2023 - Elsevier
Viral nanoparticles (VNPs) are self-assembling, adaptable delivery systems for vaccines and
other therapeutic agents used in a variety of biomedical applications. The potential of …

Virus-like particles as vaccines and vessels for the delivery of small molecules

RL Garcea, L Gissmann - Current opinion in biotechnology, 2004 - Elsevier
Virus-like particles (VLPs) structurally mimic the viral capsid and have therefore been
extensively, and quite successfully, used as vaccine and viral serology reagents. The ability …

Design of novel vaccines based on virus-like particles or chimeric virions

J Bárcena, E Blanco - Structure and Physics of Viruses: An Integrated …, 2013 - Springer
Virus-like particles (VLPs) are formed by viral structural proteins that, when overexpressed,
spontaneously self-assemble into particles that are antigenically indistinguishable from …

Virus-like particle-based nanocarriers as an emerging platform for drug delivery

B Yuan, Y Liu, M Lv, Y Sui, S Hou, T Yang… - Journal of Drug …, 2023 - Taylor & Francis
New nanocarrier technologies are emerging, and they have great potential for improving
drug delivery, targeting efficiency and bioavailability. Virus-like particles (VLPs) are natural …

Protein cargo encapsulation by virus‐like particles: Strategies and applications

D McNeale, N Dashti, LC Cheah… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Viruses and the recombinant protein cages assembled from their structural proteins, known
as virus‐like particles (VLPs), have gained wide interest as tools in biotechnology and …

Interaction of viral capsid-derived virus-like particles (VLPs) with the innate immune system

MO Mohsen, AC Gomes, M Vogel, MF Bachmann - Vaccines, 2018 - mdpi.com
Virus-like particles (VLPs) derived from viral nucleocapsids are an important class of
nanoparticles. The structure, uniformity, stability, and function of these VLPs have attracted …

Overcoming biological barriers by virus-like drug particles for drug delivery

YL Chen, CJ Bao, JL Duan, Y Xie, WL Lu - Advanced Drug Delivery …, 2023 - Elsevier
Virus-like particles (VLPs) have natural structural antigens similar to those found in viruses,
making them valuable in vaccine immunization. Furthermore, VLPs have demonstrated …

Virus-like particle vaccinology, from bench to bedside

MO Mohsen, MF Bachmann - Cellular & molecular immunology, 2022 - nature.com
Virus-like particles (VLPs) have become key tools in biology, medicine and even
engineering. After their initial use to resolve viral structures at the atomic level, VLPs were …